Pyrithyldione

Pyrithyldione
Clinical data
Trade names	Benedorm, Didropyridine, Dihydroprylone, Persedon, Presidon, Pyridion, Pyridione, Pyrithyldion, Pyrithyldione, Tetridin, Tetridine
ATC code	N05CE03 (WHO) ;
Identifiers
	IUPAC name 3,3-diethylpyridine-2,4(1H,3H)-dione;
CAS Number	77-04-3 ;
PubChem CID	4994;
ChemSpider	4820 ;
UNII	8AB20823CK;
KEGG	D07329 ;
ChEMBL	ChEMBL1722501 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C9H13NO2
Molar mass	167.205 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C1N/C=C\C(=O)C1(CC)CC;
	InChI InChI=1S/C9H13NO2/c1-3-9(4-2)7(11)5-6-10-8(9)12/h5-6H,3-4H2,1-2H3,(H,10,12) ; Key:NZASCBIBXNPDMH-UHFFFAOYSA-N ;
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Pyrithyldione (Presidon, Persedon) is a psychoactive drug invented in 1949.^[1] An improved method of manufacture was patented by Roche in 1959.^[2] It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates.^[3] Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect.^[4]^[5]

References

↑ PMID 18144514 (PMID 18144514)
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↑ US patent 3019230, Hinderling, R.; Lutz, A. H. & Schnider, O., "Method for the preparation of 2,4-dioxo-tetrahydropyridines", issued 1962-01-30, assigned to Hoffmann-La Roche
↑ Template:Cite doi
↑ PMID 10663456 (PMID 10663456)
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↑ PMID 15399031 (PMID 15399031)
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