Afloqualone

Jump to: navigation, search
Afloqualone
140px
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC16H14FN3O
Molar mass283.3

Afloqualone (Arofuto) is an analogue of methaqualone developed in the 1980s in Japan. It has sedative and muscle relaxant effects,[1] and has had some clinical use, although it causes photosensitization as a side effect which can cause skin problems such as dermatitis.[2]

See also

References

  1. Ochiai T, Ishida R. Pharmacological studies on 6-amino-2-fluoromethyl-3-(O-tolyl)-4(3H)-quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Japanese Journal of Pharmacology. 1982 Jun;32(3):427-38.
  2. Ishikawa T, Kamide R, Niimura M. Photoleukomelanodermatitis (Kobori) induced by afloqualone. Journal of Dermatology. 1994 Jun;21(6):430-3.

Template:Pharmacology-stub


Linked-in.jpg