Dichloralphenazone

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Dichloralphenazone
Combination of
PhenazoneAnalgesic
Chloral hydrateSedative
[[{{{component3}}}]]? Class
[[{{{component4}}}]]? Class
[[{{{component5}}}]]? Class
Clinical data
Routes of
administration
Oral
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. This drug acts on the blood vessels in the brain and causes them to constrict, thus relieving the pain of a headache or migrain. Additional uses of Dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.[1]

References

  1. Hindmarch I (1980). "The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses". Arzneimittelforschung. 30 (6): 1025–8. PMID 6106498. Unknown parameter |coauthors= ignored (help)

External links


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