Neuropeptide FF receptor 2: Difference between revisions

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{{Infobox_gene}}
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'''Neuropeptide FF receptor 2''', also known as '''NPFF2''' is a human [[protein]] encoded by the '''NPFFR2''' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NPFFR2 neuropeptide FF receptor 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10886| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Neuropeptide FF receptor 2
| HGNCid = 4525
| Symbol = NPFFR2
| AltSymbols =; GPR74; NPFF2; NPGPR
| OMIM = 607449
| ECnumber = 
| Homologene = 56982
| MGIid = 1860130
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008188 |text = neuropeptide receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0009582 |text = detection of abiotic stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10886
    | Hs_Ensembl = ENSG00000056291
    | Hs_RefseqProtein = NP_004876
    | Hs_RefseqmRNA = NM_004885
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 4
    | Hs_GenLoc_start = 73116385
    | Hs_GenLoc_end = 73232642
    | Hs_Uniprot = Q9Y5X5
    | Mm_EntrezGene = 104443
    | Mm_Ensembl = ENSMUSG00000035528
    | Mm_RefseqmRNA = XM_973847
    | Mm_RefseqProtein = XP_978941
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 90602628
    | Mm_GenLoc_end = 90658939
    | Mm_Uniprot = Q924N0
  }}
}}
'''Neuropeptide FF receptor 2''', also known as '''NPFFR2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NPFFR2 neuropeptide FF receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10886| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
*{{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3001 | title = Neuropeptide FF Receptors: NPFF2 | accessdate = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Cikos S, Gregor P, Koppel J |title=Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta. |journal=Biochem. Biophys. Res. Commun. |volume=256 |issue= 2 |pages= 352-6 |year= 1999 |pmid= 10079187 |doi= 10.1006/bbrc.1999.0332 }}
*{{cite journal  |vauthors=Cikos S, Gregor P, Koppel J |title=Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta. |journal=Biochem. Biophys. Res. Commun. |volume=256 |issue= 2 |pages= 352–6 |year= 1999 |pmid= 10079187 |doi= 10.1006/bbrc.1999.0332 }}
*{{cite journal | author=Parker RM, Copeland NG, Eyre HJ, ''et al.'' |title=Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. |journal=Brain Res. Mol. Brain Res. |volume=77 |issue= 2 |pages= 199-208 |year= 2000 |pmid= 10837915 |doi=  }}
*{{cite journal   |vauthors=Parker RM, Copeland NG, Eyre HJ, etal |title=Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. |journal=Brain Res. Mol. Brain Res. |volume=77 |issue= 2 |pages= 199–208 |year= 2000 |pmid= 10837915 |doi=10.1016/S0169-328X(00)00052-8 }}
*{{cite journal | author=Elshourbagy NA, Ames RS, Fitzgerald LR, ''et al.'' |title=Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. |journal=J. Biol. Chem. |volume=275 |issue= 34 |pages= 25965-71 |year= 2000 |pmid= 10851242 |doi= 10.1074/jbc.M004515200 }}
*{{cite journal   |vauthors=Elshourbagy NA, Ames RS, Fitzgerald LR, etal |title=Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. |journal=J. Biol. Chem. |volume=275 |issue= 34 |pages= 25965–71 |year= 2000 |pmid= 10851242 |doi= 10.1074/jbc.M004515200 }}
*{{cite journal | author=Bonini JA, Jones KA, Adham N, ''et al.'' |title=Identification and characterization of two G protein-coupled receptors for neuropeptide FF. |journal=J. Biol. Chem. |volume=275 |issue= 50 |pages= 39324-31 |year= 2001 |pmid= 11024015 |doi= 10.1074/jbc.M004385200 }}
*{{cite journal   |vauthors=Bonini JA, Jones KA, Adham N, etal |title=Identification and characterization of two G protein-coupled receptors for neuropeptide FF. |journal=J. Biol. Chem. |volume=275 |issue= 50 |pages= 39324–31 |year= 2001 |pmid= 11024015 |doi= 10.1074/jbc.M004385200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Laemmle B, Schindler M, Beilmann M, ''et al.'' |title=Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus. |journal=Regul. Pept. |volume=111 |issue= 1-3 |pages= 21-9 |year= 2003 |pmid= 12609745 |doi=  }}
*{{cite journal   |vauthors=Laemmle B, Schindler M, Beilmann M, etal |title=Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus. |journal=Regul. Pept. |volume=111 |issue= 1–3 |pages= 21–9 |year= 2003 |pmid= 12609745 |doi=10.1016/S0167-0115(02)00220-3 }}
*{{cite journal  | author=Engström M, Wurster S, Savola JM, Panula P |title=Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors. |journal=Peptides |volume=24 |issue= 12 |pages= 1947-54 |year= 2004 |pmid= 15127947 |doi=  }}
*{{cite journal  |vauthors=Engström M, Wurster S, Savola JM, Panula P |title=Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors |journal=Peptides |volume=24 |issue= 12 |pages= 1947–54 |year= 2004 |pmid= 15127947 |doi=10.1016/j.peptides.2003.10.009 }}
*{{cite journal  | author=Mollereau C, Mazarguil H, Zajac JM, Roumy M |title=Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells. |journal=Mol. Pharmacol. |volume=67 |issue= 3 |pages= 965-75 |year= 2005 |pmid= 15608144 |doi= 10.1124/mol.104.004614 }}
*{{cite journal  |vauthors=Mollereau C, Mazarguil H, Zajac JM, Roumy M |title=Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells |journal=Mol. Pharmacol. |volume=67 |issue= 3 |pages= 965–75 |year= 2005 |pmid= 15608144 |doi= 10.1124/mol.104.004614 }}
*{{cite journal  | author=Ankö ML, Panula P |title=Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line. |journal=J. Neurochem. |volume=96 |issue= 2 |pages= 573-84 |year= 2006 |pmid= 16336216 |doi= 10.1111/j.1471-4159.2005.03581.x }}
*{{cite journal  |vauthors=Ankö ML, Panula P |title=Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line |journal=J. Neurochem. |volume=96 |issue= 2 |pages= 573–84 |year= 2006 |pmid= 16336216 |doi= 10.1111/j.1471-4159.2005.03581.x }}
*{{cite journal  | author=Ankö ML, Ostergård M, Lintunen M, Panula P |title=Alternative splicing of human and mouse NPFF2 receptor genes: Implications to receptor expression. |journal=FEBS Lett. |volume=580 |issue= 30 |pages= 6955-60 |year= 2007 |pmid= 17157836 |doi= 10.1016/j.febslet.2006.11.063 }}
*{{cite journal  |vauthors=Ankö ML, Ostergård M, Lintunen M, Panula P |title=Alternative splicing of human and mouse NPFF2 receptor genes: Implications to receptor expression |journal=FEBS Lett. |volume=580 |issue= 30 |pages= 6955–60 |year= 2007 |pmid= 17157836 |doi= 10.1016/j.febslet.2006.11.063 }}
*{{cite journal | author=Dahlman I, Dicker A, Jiao H, ''et al.'' |title=A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis. |journal=Am. J. Hum. Genet. |volume=80 |issue= 6 |pages= 1115-24 |year= 2007 |pmid= 17503329 |doi= 10.1086/518445 }}
*{{cite journal   |vauthors=Dahlman I, Dicker A, Jiao H, etal |title=A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis |journal=Am. J. Hum. Genet. |volume=80 |issue= 6 |pages= 1115–24 |year= 2007 |pmid= 17503329 |doi= 10.1086/518445 | pmc=1867099 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:G protein coupled receptors]]
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[[Category:G protein-coupled receptors]]
{{transmembranereceptor-stub}}

Latest revision as of 12:03, 10 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Neuropeptide FF receptor 2, also known as NPFF2 is a human protein encoded by the NPFFR2 gene.[1]


See also

References

  1. "Entrez Gene: NPFFR2 neuropeptide FF receptor 2".

External links

Further reading