Hypoxia-inducible factor gene transcriptions

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Associate Editor(s)-in-Chief: Henry A. Hoff

"HIF-1 is a heterodimeric transcription factor composed of HIF-1α and HIF-1β [27]."[1]

Human genes

Interactions

Consensus sequences

The binding site for HIF-1 is GCCCTACGTGCTGTCTCA.[1]

Samplings

Copying a portion of the consensus sequence for the HIF of GCCCTACGTGCTGTCTCA and putting it in "⌘F" finds none located between ZSCAN22 and A1BG and none between ZNF497 and A1BG as can be ACTCTGTCGTGCATCCCG found by the computer programs.

For the Basic programs testing consensus sequence GCCCTACGTGCTGTCTCA (starting with SuccessablesHIF.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

  1. negative strand, negative direction, looking for GCCCTACGTGCTGTCTCA, 0.
  2. negative strand, positive direction, looking for GCCCTACGTGCTGTCTCA, 0.
  3. positive strand, negative direction, looking for GCCCTACGTGCTGTCTCA, 0.
  4. positive strand, positive direction, looking for GCCCTACGTGCTGTCTCA, 0.
  5. complement, negative strand, negative direction, looking for CGGGATGCACGACAGAGT, 0.
  6. complement, negative strand, positive direction, looking for CGGGATGCACGACAGAGT, 0.
  7. complement, positive strand, negative direction, looking for CGGGATGCACGACAGAGT, 0.
  8. complement, positive strand, positive direction, looking for CGGGATGCACGACAGAGT, 0.
  9. inverse complement, negative strand, negative direction, looking for TGAGACAGCACGTAGGGC, 0.
  10. inverse complement, negative strand, positive direction, looking for TGAGACAGCACGTAGGGC, 0.
  11. inverse complement, positive strand, negative direction, looking for TGAGACAGCACGTAGGGC, 0.
  12. inverse complement, positive strand, positive direction, looking for TGAGACAGCACGTAGGGC, 0.
  13. inverse negative strand, negative direction, looking for ACTCTGTCGTGCATCCCG, 0.
  14. inverse negative strand, positive direction, looking for ACTCTGTCGTGCATCCCG, 0.
  15. inverse positive strand, negative direction, looking for ACTCTGTCGTGCATCCCG, 0.
  16. inverse positive strand, positive direction, looking for ACTCTGTCGTGCATCCCG, 0.

See also

References

  1. 1.0 1.1 Qingliang Li, Rezaul M. Karim, Mo Cheng, Mousumi Das, Lihong Chen, Chen Zhang, Harshani R. Lawrence, Gary W. Daughdrill, Ernst Schonbrunn, Haitao Ji and Jiandong Chen (July 2020). "Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity". Oncogene. 39 (29): 5187–5200. doi:10.1038/s41388-020-1344-y. PMID 32555331 Check |pmid= value (help). Retrieved 29 August 2020.

External links