Sip4p gene transcriptions

Associate Editor(s)-in-Chief: Henry A. Hoff

The UAS sequence for the transcription factor Sip4p is CCRTYCRTCCG, which occurs in the promoters of FBP1, PKC1, ICL1 genes in S. cerevisiae, with no inducer, used for positive regulation of gluconeogenesis.^[1]

Human genes

Gene expressions

Interactions

Consensus sequences

Sip4p consensus sequence is CC(C/G)T(C/T)C(C/G)TCCG.^[1]

Binding site for

Positive regulation of gluconeogenesis.^[1]

Promoter occurrences

Occurs in the promoters of FBP1, PKC1, ICL1 genes in S. cerevisiae.<ref name=Tang>

Hypotheses

A1BG has no regulatory elements in either promoter.
A1BG is not transcribed by a regulatory element.
No regulatory element participates in the transcription of A1BG.

SIP samplings

Copying a responsive elements consensus sequence CC(C/G)T(C/T)C(C/G)TCCG and putting the sequence in "⌘F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence CC(C/G)T(C/T)C(C/G)TCCG (starting with SuccessablesSIP.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
positive strand, negative direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
positive strand, positive direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
negative strand, positive direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
complement, negative strand, negative direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
complement, positive strand, negative direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
complement, positive strand, positive direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
complement, negative strand, positive direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
inverse complement, negative strand, negative direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
inverse complement, positive strand, negative direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
inverse complement, positive strand, positive direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
inverse complement, negative strand, positive direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
inverse negative strand, negative direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.
inverse positive strand, negative direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.
inverse positive strand, positive direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.
inverse negative strand, positive direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

References

↑ ^1.0 ^1.1 ^1.2 Hongting Tang, Yanling Wu, Jiliang Deng, Nanzhu Chen, Zhaohui Zheng, Yongjun Wei, Xiaozhou Luo, and Jay D. Keasling (6 August 2020). "Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae". Metabolites. 10 (8): 320–39. doi:10.3390/metabo10080320. PMID 32781665 Check |pmid= value (help). Retrieved 18 September 2020.

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