Sterol response element gene transcriptions

Associate Editor(s)-in-Chief: Henry A. Hoff

"These genomic sequences were analysed for the presence of sterol-response elements (SRE) motif (5'-TCGTATA-3') [...] using the NCBI BLAST tool."^[1]

Human genes

Consensus sequences

Consensus sequence for the sterol regulatory element is AGCAGATTGCG or CAGCAGATTGCG.^[2]

SRE (Branco) samplings

Copying the SRE consensus: TCGTATA and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence TCGTATA (starting with SuccessablesSREB.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for TCGTATA, 0.
positive strand, negative direction, looking for TCGTATA, 0.
positive strand, positive direction, looking for TCGTATA, 0.
negative strand, positive direction, looking for TCGTATA, 0.
complement, negative strand, negative direction, looking for AGCATAT, 0.
complement, positive strand, negative direction, looking for AGCATAT, 0.
complement, positive strand, positive direction, looking for AGCATAT, 0.
complement, negative strand, positive direction, looking for AGCATAT, 0.
inverse complement, negative strand, negative direction, looking for TATACGA, 0.
inverse complement, positive strand, negative direction, looking for TATACGA, 0.
inverse complement, positive strand, positive direction, looking for TATACGA, 0.
inverse complement, negative strand, positive direction, looking for TATACGA, 0.
inverse negative strand, negative direction, looking for ATATGCT, 0.
inverse positive strand, negative direction, looking for ATATGCT, 0.
inverse positive strand, positive direction, looking for ATATGCT, 0.
inverse negative strand, positive direction, looking for ATATGCT, 0.

SRE (Yao) samplings

Copying the SRE consensus: NAGCAGATTGCG and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence NAGCAGATTGCG (starting with SuccessablesSREY.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for NAGCAGATTGCG, 0.
positive strand, negative direction, looking for NAGCAGATTGCG, 0.
positive strand, positive direction, looking for NAGCAGATTGCG, 0.
negative strand, positive direction, looking for NAGCAGATTGCG, 0.
complement, negative strand, negative direction, looking for NTCATCTAACGC, 0.
complement, positive strand, negative direction, looking for NTCATCTAACGC, 0.
complement, positive strand, positive direction, looking for NTCATCTAACGC, 0.
complement, negative strand, positive direction, looking for NTCATCTAACGC, 0.
inverse complement, negative strand, negative direction, looking for CGCAATCTACTN, 0.
inverse complement, positive strand, negative direction, looking for CGCAATCTACTN, 0.
inverse complement, positive strand, positive direction, looking for CGCAATCTACTN, 0.
inverse complement, negative strand, positive direction, looking for CGCAATCTACTN, 0.
inverse negative strand, negative direction, looking for GCGTTAGACGAN, 0.
inverse positive strand, negative direction, looking for GCGTTAGACGAN, 0.
inverse positive strand, positive direction, looking for GCGTTAGACGAN, 0.
inverse negative strand, positive direction, looking for GCGTTAGACGAN, 0.

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

References

↑ J. Branco, M. Ola, R. M. Silva, E. Fonseca, N. C. Gomes, C. Martins-Cruz, A. P. Silva, A. Silva-Dias, C. Pina-Vaz, C. Erraught, L. Brennan, A. G. Rodrigues, G. Butler and I. M. Miranda (August 2017). "Impact of ERG3 mutations and expression of ergosterol genes controlled by UPC2 and NDT80 in Candida parapsilosis azole resistance". Clinical Microbiology and Infection. 23 (8): 575.e1–575.e8. doi:10.1016/j.cmi.2017.02.002. PMID 28196695. Retrieved 5 September 2020.
↑ D. W. Yao, J. Luo, Q. Y. He, J. Li, H. Wang, H. B. Shi, H. F. Xu, M. Wang and J. J. Loor (May 2016). "Characterization of the liver X receptor-dependent regulatory mechanism of goat stearoyl-coenzyme A desaturase 1 gene by linoleic acid". Journal of Dairy Science. 99 (5): 3945–3957. doi:10.3168/jds.2015-10601. PMID 26947306. Retrieved 5 September 2020.

External links

[Branco-1] J. Branco, M. Ola, R. M. Silva, E. Fonseca, N. C. Gomes, C. Martins-Cruz, A. P. Silva, A. Silva-Dias, C. Pina-Vaz, C. Erraught, L. Brennan, A. G. Rodrigues, G. Butler and I. M. Miranda (August 2017). "Impact of ERG3 mutations and expression of ergosterol genes controlled by UPC2 and NDT80 in Candida parapsilosis azole resistance". Clinical Microbiology and Infection. 23 (8): 575.e1–575.e8. doi:10.1016/j.cmi.2017.02.002. PMID 28196695. Retrieved 5 September 2020.

[Yao2016-2] D. W. Yao, J. Luo, Q. Y. He, J. Li, H. Wang, H. B. Shi, H. F. Xu, M. Wang and J. J. Loor (May 2016). "Characterization of the liver X receptor-dependent regulatory mechanism of goat stearoyl-coenzyme A desaturase 1 gene by linoleic acid". Journal of Dairy Science. 99 (5): 3945–3957. doi:10.3168/jds.2015-10601. PMID 26947306. Retrieved 5 September 2020.

[1]

[2]

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transcriptions Ste12p gene transcriptions Sterol response element gene transcriptions Sucrose box gene transcriptions Synaptic Activity-Responsive Elements TACTAAC box gene transcriptions TAGteam gene transcriptions Tapetum box gene transcriptions TATA binding protein associated factor gene transcriptions TATA binding protein gene transcriptions TATA box gene transcriptions TAT box gene transcriptions TATC box gene transcriptions Tbf1 regulatory factor gene transcriptions T box gene transcriptions TCCACCATA element gene transcriptions TC element gene transcriptions TCT gene transcriptions TEA consensus sequence gene transcriptions Tec1p gene transcriptions Telomeric repeat DNA-binding factor gene transcriptions Tetradecanoylphorbol-13-acetate response element gene transcriptions TGF-β control elements (TCEs) TGF-β inhibitory elements (TIEs) Thyroid hormone response element gene transcriptions Transcriptional regulation Transcription bubble gene transcriptions Transcription factor gene 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