GPR63: Difference between revisions

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{{Infobox_gene}}
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'''Probable G-protein coupled receptor 63''' is a [[protein]] that in humans is encoded by the ''GPR63'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR63 G protein-coupled receptor 63| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81491| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = G protein-coupled receptor 63
| HGNCid = 13302
| Symbol = GPR63
| AltSymbols =; PSP24(beta); PSP24B
| OMIM = 606915
| ECnumber = 
| Homologene = 12759
| MGIid = 2135884
| GeneAtlas_image1 = PBB_GE_GPR63_220993_s_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0008150 |text = biological_process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 81491
    | Hs_Ensembl = ENSG00000112218
    | Hs_RefseqProtein = NP_110411
    | Hs_RefseqmRNA = NM_030784
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 6
    | Hs_GenLoc_start = 97352645
    | Hs_GenLoc_end = 97391921
    | Hs_Uniprot = Q9BZJ6
    | Mm_EntrezGene = 81006
    | Mm_Ensembl = ENSMUSG00000040372
    | Mm_RefseqmRNA = NM_030733
    | Mm_RefseqProtein = NP_109658
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 25064049
    | Mm_GenLoc_end = 25099863
    | Mm_Uniprot = Q8BZ93
  }}
}}
'''G protein-coupled receptor 63''', also known as '''GPR63''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR63 G protein-coupled receptor 63| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81491| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: GPR63 G protein-coupled receptor 63| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81491| accessdate = }}</ref>
| summary_text = G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: GPR63 G protein-coupled receptor 63| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81491| accessdate = }}</ref>
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Kawasawa Y, Kume K, Nakade S, ''et al.'' |title=Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 3 |pages= 952-6 |year= 2000 |pmid= 11027574 |doi= 10.1006/bbrc.2000.3569 }}
*{{cite journal   |vauthors=Kawasawa Y, Kume K, Nakade S, etal |title=Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 3 |pages= 952–6 |year= 2000 |pmid= 11027574 |doi= 10.1006/bbrc.2000.3569 }}
*{{cite journal  | author=Kawasawa Y, Kume K, Izumi T, Shimizu T |title=Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 3 |pages= 957-64 |year= 2000 |pmid= 11027575 |doi= 10.1006/bbrc.2000.3570 }}
*{{cite journal  |vauthors=Kawasawa Y, Kume K, Izumi T, Shimizu T |title=Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 3 |pages= 957–64 |year= 2000 |pmid= 11027575 |doi= 10.1006/bbrc.2000.3570 }}
*{{cite journal | author=Lee DK, George SR, Cheng R, ''et al.'' |title=Identification of four novel human G protein-coupled receptors expressed in the brain. |journal=Brain Res. Mol. Brain Res. |volume=86 |issue= 1-2 |pages= 13-22 |year= 2001 |pmid= 11165367 |doi=  }}
*{{cite journal   |vauthors=Lee DK, George SR, Cheng R, etal |title=Identification of four novel human G protein-coupled receptors expressed in the brain. |journal=Brain Res. Mol. Brain Res. |volume=86 |issue= 1–2 |pages= 13–22 |year= 2001 |pmid= 11165367 |doi=10.1016/S0169-328X(00)00242-4 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Niedernberg A, Tunaru S, Blaukat A, ''et al.'' |title=Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63. |journal=Cell. Signal. |volume=15 |issue= 4 |pages= 435-46 |year= 2004 |pmid= 12618218 |doi=  }}
*{{cite journal   |vauthors=Niedernberg A, Tunaru S, Blaukat A, etal |title=Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63 |journal=Cell. Signal. |volume=15 |issue= 4 |pages= 435–46 |year= 2004 |pmid= 12618218 |doi=10.1016/S0898-6568(02)00119-5 }}
*{{cite journal | author=Mungall AJ, Palmer SA, Sims SK, ''et al.'' |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal   |vauthors=Mungall AJ, Palmer SA, Sims SK, etal |title=The DNA sequence and analysis of human chromosome 6 |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
}}
}}
{{refend}}
{{refend}}


{{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}
 
 
{{transmembranereceptor-stub}}

Revision as of 09:01, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 63 is a protein that in humans is encoded by the GPR63 gene.[1]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][1]

References

  1. ↑ 1.0 1.1 "Entrez Gene: GPR63 G protein-coupled receptor 63".

Further reading


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