GPR15: Difference between revisions

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{{Infobox_gene}}
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'''G-protein coupled receptor 15''' is a [[protein]] that in humans is encoded by the ''GPR15'' [[gene]].<ref name="pmid8838812">{{cite journal |vauthors=Heiber M, Marchese A, Nguyen T, Heng HH, George SR, O'Dowd BF | title = A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3 | journal = Genomics | volume = 32 | issue = 3 | pages = 462–5 |date=Feb 1997 | pmid = 8838812 | pmc =  | doi = 10.1006/geno.1996.0143 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPR15 G protein-coupled receptor 15| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2838| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = G protein-coupled receptor 15
| HGNCid = 4469
| Symbol = GPR15
| AltSymbols =; MGC126828; MGC126830
| OMIM = 601166
| ECnumber = 
| Homologene = 3869
| MGIid = 1918473
| GeneAtlas_image1 = PBB_GE_GPR15_208524_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0045028 |text = purinergic nucleotide receptor activity, G-protein coupled}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2838
    | Hs_Ensembl = ENSG00000154165
    | Hs_RefseqProtein = NP_005281
    | Hs_RefseqmRNA = NM_005290
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 99733568
    | Hs_GenLoc_end = 99734650
    | Hs_Uniprot = P49685
    | Mm_EntrezGene = 71223
    | Mm_Ensembl = ENSMUSG00000047293
    | Mm_RefseqmRNA = XM_001002039
    | Mm_RefseqProtein = XP_001002039
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 58660185
    | Mm_GenLoc_end = 58661267
    | Mm_Uniprot = 
  }}
}}
'''G protein-coupled receptor 15''', also known as '''GPR15''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR15 G protein-coupled receptor 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2838| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Cunningham AL, Li S, Juarez J, ''et al.'' |title=The level of HIV infection of macrophages is determined by interaction of viral and host cell genotypes. |journal=J. Leukoc. Biol. |volume=68 |issue= 3 |pages= 311-7 |year= 2000 |pmid= 10985245 |doi=  }}
*{{cite journal  | author=Cunningham AL |title=The level of HIV infection of macrophages is determined by interaction of viral and host cell genotypes |journal=J. Leukoc. Biol. |volume=68 |issue= 3 |pages= 311–7 |year= 2000 |pmid= 10985245 |doi=  |name-list-format=vanc| author2=Li S | author3=Juarez J  | display-authors=3 | last4=Lynch  | first4=| last5=Alali  | first5=| last6=Naif  | first6=}}
*{{cite journal | author=Heiber M, Marchese A, Nguyen T, ''et al.'' |title=A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. |journal=Genomics |volume=32 |issue= 3 |pages= 462-5 |year= 1997 |pmid= 8838812 |doi= 10.1006/geno.1996.0143 }}
*{{cite journal  |vauthors=Deng HK, Unutmaz D, KewalRamani VN, Littman DR |title=Expression cloning of new receptors used by simian and human immunodeficiency viruses |journal=Nature |volume=388 |issue= 6639 |pages= 296–300 |year= 1997 |pmid= 9230441 |doi= 10.1038/40894 }}
*{{cite journal  | author=Deng HK, Unutmaz D, KewalRamani VN, Littman DR |title=Expression cloning of new receptors used by simian and human immunodeficiency viruses. |journal=Nature |volume=388 |issue= 6639 |pages= 296-300 |year= 1997 |pmid= 9230441 |doi= 10.1038/40894 }}
*{{cite journal  | author=Farzan M |title=Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection |journal=J. Exp. Med. |volume=186 |issue= 3 |pages= 405–11 |year= 1997 |pmid= 9236192 |doi=10.1084/jem.186.3.405  | pmc=2198994  |name-list-format=vanc| author2=Choe H  | author3=Martin K  | display-authors=3  | last4=Marcon  | first4=L  | last5=Hofmann  | first5=W  | last6=Karlsson  | first6=G  | last7=Sun  | first7=Y  | last8=Barrett  | first8=P  | last9=Marchand  | first9=N }}
*{{cite journal  | author=Farzan M, Choe H, Martin K, ''et al.'' |title=Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. |journal=J. Exp. Med. |volume=186 |issue= 3 |pages= 405-11 |year= 1997 |pmid= 9236192 |doi=  }}
*{{cite journal  | author=Clayton F |title=Gp120-Induced Bob/GPR15 Activation : A Possible Cause of Human Immunodeficiency Virus Enteropathy |journal=Am. J. Pathol. |volume=159 |issue= 5 |pages= 1933–9 |year= 2001 |pmid= 11696454 |doi= 10.1016/S0002-9440(10)63040-4| pmc=1867054  |name-list-format=vanc| author2=Kotler DP  | author3=Kuwada SK  | display-authors=3  | last4=Morgan  | first4=T  | last5=Stepan  | first5=C  | last6=Kuang  | first6=J  | last7=Le  | first7=J  | last8=Fantini  | first8=J }}
*{{cite journal  | author=Clayton F, Kotler DP, Kuwada SK, ''et al.'' |title=Gp120-induced Bob/GPR15 activation: a possible cause of human immunodeficiency virus enteropathy. |journal=Am. J. Pathol. |volume=159 |issue= 5 |pages= 1933-9 |year= 2001 |pmid= 11696454 |doi=  }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Croitoru-Lamoury J |title=Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation |journal=Glia |volume=41 |issue= 4 |pages= 354–70 |year= 2003 |pmid= 12555203 |doi= 10.1002/glia.10181 |name-list-format=vanc| author2=Guillemin GJ  | author3=Boussin FD  | display-authors=3  | last4=Mognetti  | first4=Barbara  | last5=Gigout  | first5=Laure I.  | last6=Charet  | first6=Arnaud  | last7=Vaslin  | first7=Bruno  | last8=Le Grand  | first8=Roger  | last9=Brew  | first9=Bruce J. }}
*{{cite journal  | author=Croitoru-Lamoury J, Guillemin GJ, Boussin FD, ''et al.'' |title=Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation. |journal=Glia |volume=41 |issue= 4 |pages= 354-70 |year= 2003 |pmid= 12555203 |doi= 10.1002/glia.10181 }}
*{{cite journal  | author=Maresca M |title=The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line |journal=J. Biomed. Sci. |volume=10 |issue= 1 |pages= 156–66 |year= 2003 |pmid= 12566994 |doi= 10.1159/000068089 |name-list-format=vanc| author2=Mahfoud R  | author3=Garmy N  | display-authors=3  | last4=Kotler  | first4=Donald P.  | last5=Fantini  | first5=Jacques  | last6=Clayton  | first6=Frederic }}
*{{cite journal  | author=Maresca M, Mahfoud R, Garmy N, ''et al.'' |title=The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line. |journal=J. Biomed. Sci. |volume=10 |issue= 1 |pages= 156-66 |year= 2003 |pmid= 12566994 |doi= 10.1159/000068089 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Blaak H |title=CCR5, GPR15, and CXCR6 Are Major Coreceptors of Human Immunodeficiency Virus Type 2 Variants Isolated from Individuals with and without Plasma Viremia |journal=J. Virol. |volume=79 |issue= 3 |pages= 1686–700 |year= 2005 |pmid= 15650194 |doi= 10.1128/JVI.79.3.1686-1700.2005 | pmc=544080  |name-list-format=vanc| author2=Boers PH  | author3=Gruters RA  | display-authors=3  | last4=Schuitemaker  | first4=H.  | last5=Van Der Ende  | first5=M. E.  | last6=Osterhaus  | first6=A. D. M. E. }}
*{{cite journal  | author=Blaak H, Boers PH, Gruters RA, ''et al.'' |title=CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia. |journal=J. Virol. |volume=79 |issue= 3 |pages= 1686-700 |year= 2005 |pmid= 15650194 |doi= 10.1128/JVI.79.3.1686-1700.2005 }}
*{{cite journal  | author=Cilliers T |title=Use of alternate coreceptors on primary cells by two HIV-1 isolates |journal=Virology |volume=339 |issue= 1 |pages= 136–44 |year= 2005 |pmid= 15992849 |doi= 10.1016/j.virol.2005.05.027 |name-list-format=vanc| author2=Willey S  | author3=Sullivan WM  | display-authors=3  | last4=Patience  | first4=T  | last5=Pugach  | first5=P  | last6=Coetzer  | first6=M  | last7=Papathanasopoulos  | first7=M  | last8=Moore  | first8=J  | last9=Trkola  | first9=A }}
*{{cite journal  | author=Cilliers T, Willey S, Sullivan WM, ''et al.'' |title=Use of alternate coreceptors on primary cells by two HIV-1 isolates. |journal=Virology |volume=339 |issue= 1 |pages= 136-44 |year= 2005 |pmid= 15992849 |doi= 10.1016/j.virol.2005.05.027 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:G protein coupled receptors]]
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[[Category:G protein-coupled receptors]]
{{transmembranereceptor-stub}}

Latest revision as of 18:00, 24 September 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

G-protein coupled receptor 15 is a protein that in humans is encoded by the GPR15 gene.[1][2]


References

  1. Heiber M, Marchese A, Nguyen T, Heng HH, George SR, O'Dowd BF (Feb 1997). "A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3". Genomics. 32 (3): 462–5. doi:10.1006/geno.1996.0143. PMID 8838812.
  2. "Entrez Gene: GPR15 G protein-coupled receptor 15".

Further reading