Alpha-1D adrenergic receptor: Difference between revisions

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{{Infobox_gene}}
 
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Adrenergic, alpha-1D-, receptor
| HGNCid = 280
| Symbol = ADRA1D
| AltSymbols =; ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2
| OMIM = 104219
| ECnumber = 
| Homologene = 551
| MGIid = 106673
| GeneAtlas_image1 = PBB_GE_ADRA1D_210961_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_ADRA1D_210960_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004935 |text = adrenoceptor activity}} {{GNF_GO|id=GO:0004937 |text = alpha1-adrenergic receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006259 |text = DNA metabolic process}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007188 |text = G-protein signaling, coupled to cAMP nucleotide second messenger}} {{GNF_GO|id=GO:0007267 |text = cell-cell signaling}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 146
    | Hs_Ensembl = ENSG00000171873
    | Hs_RefseqProtein = NP_000669
    | Hs_RefseqmRNA = NM_000678
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 20
    | Hs_GenLoc_start = 4149329
    | Hs_GenLoc_end = 4177659
    | Hs_Uniprot = P25100
    | Mm_EntrezGene = 11550
    | Mm_Ensembl = ENSMUSG00000027335
    | Mm_RefseqmRNA = NM_013460
    | Mm_RefseqProtein = NP_038488
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 131237291
    | Mm_GenLoc_end = 131253726
    | Mm_Uniprot = P97714
  }}
}}
The '''alpha-1D adrenergic receptor''' (α<sub>1D</sub> adrenoreceptor), also known as '''ADRA1D''', is an [[alpha-1 adrenergic receptor]], and also denotes the human [[gene]] encoding it.<ref name="entrez" />
The '''alpha-1D adrenergic receptor''' (α<sub>1D</sub> adrenoreceptor), also known as '''ADRA1D''', is an [[alpha-1 adrenergic receptor]], and also denotes the human [[gene]] encoding it.<ref name="entrez" />
<!-- The PBB_Summary template is not automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Continue updates. -->
{{PBB_Summary
| section_title =
| summary_text =


==Receptor==
==Receptor==
Line 60: Line 6:


==Gene==
==Gene==
This gene encodes alpha-1D-adrenergic receptor. Similar to [[alpha-1B-adrenergic receptor]] gene, this gene comprises 2 [[exons]] and a single [[intron]] that interrupts the coding region.<ref name="entrez">{{cite web | title = Entrez Gene: ADRA1D adrenergic, alpha-1D-, receptor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=146| accessdate = }}</ref>
This gene encodes alpha-1D-adrenergic receptor. Similar to [[alpha-1B-adrenergic receptor]] gene, this gene comprises 2 [[exons]] and a single [[intron]] that interrupts the coding region.<ref name="entrez">{{cite web | title = Entrez Gene: ADRA1D adrenergic, alpha-1D-, receptor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=146| accessdate = }}</ref>
}}
 
==Ligands==
; Antagonists
* A-315456<ref name="pmid11755142">{{cite journal | vauthors = Buckner SA, Milicic I, Daza A, Lynch JJ, Kolasa T, Nakane M, Sullivan JP, Brioni JD | title = A-315456: a selective alpha(1D)-adrenoceptor antagonist with minimal dopamine D(2) and 5-HT(1A) receptor affinity | journal = Eur. J. Pharmacol. | volume = 433 | issue = 1 | pages = 123–7 | year = 2001 | pmid = 11755142 |doi=10.1016/s0014-2999(01)01519-9 }}</ref>
* BMY 7378 (also [[Alpha-2C adrenergic receptor|α<sub>2C</sub>]] antagonist)<ref name="pmid16176444">{{cite journal | vauthors = Cleary L, Murad K, Bexis S, Docherty JR | title = The alpha (1D)-adrenoceptor antagonist BMY 7378 is also an alpha (2C)-adrenoceptor antagonist | journal = Auton Autacoid Pharmacol | volume = 25 | issue = 4 | pages = 135–41 | year = 2005 | pmid = 16176444 | doi = 10.1111/j.1474-8673.2005.00342.x }}</ref>


==See also==
==See also==
Line 67: Line 17:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|ADRA1A}}
* {{UCSC gene info|ADRA1D}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
*{{cite journal  | vauthors=Schwinn DA, Lomasney JW |title=Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype. |journal=Eur. J. Pharmacol. |volume=227 |issue= 4 |pages= 433–6 |year= 1992 |pmid= 1359975 |doi=10.1016/0922-4106(92)90162-O }}
| citations =
*{{cite journal  | vauthors=Bruno JF, Whittaker J, Song JF, Berelowitz M |title=Molecular cloning and sequencing of a cDNA encoding a human alpha 1A adrenergic receptor. |journal=Biochem. Biophys. Res. Commun. |volume=179 |issue= 3 |pages= 1485–90 |year= 1991 |pmid= 1656955 |doi=10.1016/0006-291X(91)91740-4 }}
*{{cite journal  | author=Schwinn DA, Lomasney JW |title=Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype. |journal=Eur. J. Pharmacol. |volume=227 |issue= 4 |pages= 433-6 |year= 1992 |pmid= 1359975 |doi=  }}
*{{cite journal  | vauthors=Esbenshade TA, Hirasawa A, Tsujimoto G |title=Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells. |journal=Mol. Pharmacol. |volume=47 |issue= 5 |pages= 977–85 |year= 1995 |pmid= 7746284 |doi=  |display-authors=etal}}
*{{cite journal  | author=Bruno JF, Whittaker J, Song JF, Berelowitz M |title=Molecular cloning and sequencing of a cDNA encoding a human alpha 1A adrenergic receptor. |journal=Biochem. Biophys. Res. Commun. |volume=179 |issue= 3 |pages= 1485-90 |year= 1991 |pmid= 1656955 |doi=  }}
*{{cite journal  | vauthors=Schwinn DA, Johnston GI, Page SO |title=Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. |journal=J. Pharmacol. Exp. Ther. |volume=272 |issue= 1 |pages= 134–42 |year= 1995 |pmid= 7815325 |doi=  |display-authors=etal}}
*{{cite journal  | author=Esbenshade TA, Hirasawa A, Tsujimoto G, ''et al.'' |title=Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells. |journal=Mol. Pharmacol. |volume=47 |issue= 5 |pages= 977-85 |year= 1995 |pmid= 7746284 |doi=  }}
*{{cite journal  | vauthors=Weinberg DH, Trivedi P, Tan CP |title=Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c. |journal=Biochem. Biophys. Res. Commun. |volume=201 |issue= 3 |pages= 1296–304 |year= 1994 |pmid= 8024574 |doi=10.1006/bbrc.1994.1845 |display-authors=etal}}
*{{cite journal  | author=Schwinn DA, Johnston GI, Page SO, ''et al.'' |title=Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. |journal=J. Pharmacol. Exp. Ther. |volume=272 |issue= 1 |pages= 134-42 |year= 1995 |pmid= 7815325 |doi=  }}
*{{cite journal  | vauthors=Loftus SK, Shiang R, Warrington JA |title=Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5. |journal=Cytogenet. Cell Genet. |volume=67 |issue= 2 |pages= 69–74 |year= 1994 |pmid= 8039425 |doi=10.1159/000133802 |display-authors=etal}}
*{{cite journal  | author=Weinberg DH, Trivedi P, Tan CP, ''et al.'' |title=Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c. |journal=Biochem. Biophys. Res. Commun. |volume=201 |issue= 3 |pages= 1296-304 |year= 1994 |pmid= 8024574 |doi=  }}
*{{cite journal  | vauthors=Yang-Feng TL, Han H, Lomasney JW, Caron MG |title=Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13. |journal=Cytogenet. Cell Genet. |volume=66 |issue= 3 |pages= 170–1 |year= 1994 |pmid= 8125015 |doi=10.1159/000133693 }}
*{{cite journal  | author=Loftus SK, Shiang R, Warrington JA, ''et al.'' |title=Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5. |journal=Cytogenet. Cell Genet. |volume=67 |issue= 2 |pages= 69-74 |year= 1994 |pmid= 8039425 |doi=  }}
*{{cite journal  | vauthors=Forray C, Bard JA, Wetzel JM |title=The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype. |journal=Mol. Pharmacol. |volume=45 |issue= 4 |pages= 703–8 |year= 1994 |pmid= 8183249 |doi=  |display-authors=etal}}
*{{cite journal  | author=Yang-Feng TL, Han H, Lomasney JW, Caron MG |title=Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13. |journal=Cytogenet. Cell Genet. |volume=66 |issue= 3 |pages= 170-1 |year= 1994 |pmid= 8125015 |doi=  }}
*{{cite journal  | vauthors=Minneman KP, Lee D, Zhong H |title=Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: comparison of alpha(1)-adrenergic receptor subtypes. |journal=J. Neurochem. |volume=74 |issue= 6 |pages= 2392–400 |year= 2000 |pmid= 10820200 |doi=10.1046/j.1471-4159.2000.0742392.x  |display-authors=etal}}
*{{cite journal  | author=Forray C, Bard JA, Wetzel JM, ''et al.'' |title=The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype. |journal=Mol. Pharmacol. |volume=45 |issue= 4 |pages= 703-8 |year= 1994 |pmid= 8183249 |doi=  }}
*{{cite journal  | vauthors=Keffel S, Alexandrov A, Goepel M, Michel MC |title=alpha(1)-adrenoceptor subtypes differentially couple to growth promotion and inhibition in Chinese hamster ovary cells. |journal=Biochem. Biophys. Res. Commun. |volume=272 |issue= 3 |pages= 906–11 |year= 2000 |pmid= 10860850 |doi= 10.1006/bbrc.2000.2850 }}
*{{cite journal  | author=Minneman KP, Lee D, Zhong H, ''et al.'' |title=Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: comparison of alpha(1)-adrenergic receptor subtypes. |journal=J. Neurochem. |volume=74 |issue= 6 |pages= 2392-400 |year= 2000 |pmid= 10820200 |doi= }}
*{{cite journal  | vauthors=Kyprianou N, Benning CM |title=Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis. |journal=Cancer Res. |volume=60 |issue= 16 |pages= 4550–5 |year= 2000 |pmid= 10969806 |doi=  }}
*{{cite journal  | author=Keffel S, Alexandrov A, Goepel M, Michel MC |title=alpha(1)-adrenoceptor subtypes differentially couple to growth promotion and inhibition in Chinese hamster ovary cells. |journal=Biochem. Biophys. Res. Commun. |volume=272 |issue= 3 |pages= 906-11 |year= 2000 |pmid= 10860850 |doi= 10.1006/bbrc.2000.2850 }}
*{{cite journal  | vauthors=Deloukas P, Matthews LH, Ashurst J |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a |display-authors=etal}}
*{{cite journal  | author=Kyprianou N, Benning CM |title=Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis. |journal=Cancer Res. |volume=60 |issue= 16 |pages= 4550-5 |year= 2000 |pmid= 10969806 |doi=  }}
*{{cite journal  | vauthors=Shibata K, Katsuma S, Koshimizu T |title=alpha 1-Adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1. |journal=J. Biol. Chem. |volume=278 |issue= 1 |pages= 672–8 |year= 2003 |pmid= 12409310 |doi= 10.1074/jbc.M201375200 |display-authors=etal}}
*{{cite journal  | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
*{{cite journal  | vauthors=Pupo AS, Minneman KP |title=Specific interactions between gC1qR and alpha1-adrenoceptor subtypes. |journal=J. Recept. Signal Transduct. Res. |volume=23 |issue= 2–3 |pages= 185–95 |year= 2004 |pmid= 14626446 |doi=10.1081/RRS-120025200 }}
*{{cite journal  | author=Shibata K, Katsuma S, Koshimizu T, ''et al.'' |title=alpha 1-Adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1. |journal=J. Biol. Chem. |volume=278 |issue= 1 |pages= 672-8 |year= 2003 |pmid= 12409310 |doi= 10.1074/jbc.M201375200 }}
*{{cite journal  | vauthors=Hague C, Uberti MA, Chen Z |title=Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors |journal=J. Biol. Chem. |volume=279 |issue= 15 |pages= 15541–9 |year= 2004 |pmid= 14736874 |doi= 10.1074/jbc.M314014200 |display-authors=etal}}
*{{cite journal  | author=Pupo AS, Minneman KP |title=Specific interactions between gC1qR and alpha1-adrenoceptor subtypes. |journal=J. Recept. Signal Transduct. Res. |volume=23 |issue= 2-3 |pages= 185-95 |year= 2004 |pmid= 14626446 |doi=  }}
*{{cite journal  | vauthors=Gonzalez-Cabrera PJ, Shi T, Yun J |title=Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes |journal=Endocrinology |volume=145 |issue= 11 |pages= 5157–67 |year= 2004 |pmid= 15297446 |doi= 10.1210/en.2004-0728 |display-authors=etal}}
*{{cite journal  | author=Hague C, Uberti MA, Chen Z, ''et al.'' |title=Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors. |journal=J. Biol. Chem. |volume=279 |issue= 15 |pages= 15541-9 |year= 2004 |pmid= 14736874 |doi= 10.1074/jbc.M314014200 }}
*{{cite journal  | vauthors=Zhang T, Xu Q, Chen FR |title=Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors |journal=Acta Pharmacol. Sin. |volume=25 |issue= 11 |pages= 1471–8 |year= 2005 |pmid= 15525470 |doi=  |display-authors=etal}}
*{{cite journal  | author=Gonzalez-Cabrera PJ, Shi T, Yun J, ''et al.'' |title=Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes. |journal=Endocrinology |volume=145 |issue= 11 |pages= 5157-67 |year= 2004 |pmid= 15297446 |doi= 10.1210/en.2004-0728 }}
*{{cite journal  | vauthors=Sigala S, Dellabella M, Milanese G |title=Evidence for the presence of alpha1 adrenoceptor subtypes in the human ureter |journal=Neurourol. Urodyn. |volume=24 |issue= 2 |pages= 142–8 |year= 2005 |pmid= 15690361 |doi= 10.1002/nau.20097 |display-authors=etal}}
*{{cite journal  | author=Zhang T, Xu Q, Chen FR, ''et al.'' |title=Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors. |journal=Acta Pharmacol. Sin. |volume=25 |issue= 11 |pages= 1471-8 |year= 2005 |pmid= 15525470 |doi=  }}
*{{cite journal  | vauthors=Chen Z, Hague C, Hall RA, Minneman KP |title=Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction |journal=J. Biol. Chem. |volume=281 |issue= 18 |pages= 12414–20 |year= 2006 |pmid= 16533813 |doi= 10.1074/jbc.M508651200 }}
*{{cite journal  | author=Sigala S, Dellabella M, Milanese G, ''et al.'' |title=Evidence for the presence of alpha1 adrenoceptor subtypes in the human ureter. |journal=Neurourol. Urodyn. |volume=24 |issue= 2 |pages= 142-8 |year= 2005 |pmid= 15690361 |doi= 10.1002/nau.20097 }}
*{{cite journal  | vauthors=Michelotti GA, Brinkley DM, Morris DP |title=Epigenetic regulation of human α1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation |journal=FASEB J. |volume=21 |issue= 9 |pages= 1979–93 |year= 2007 |pmid= 17384146 |doi= 10.1096/fj.06-7118com | pmc=2279228 |display-authors=etal}}
*{{cite journal  | author=Chen Z, Hague C, Hall RA, Minneman KP |title=Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction. |journal=J. Biol. Chem. |volume=281 |issue= 18 |pages= 12414-20 |year= 2006 |pmid= 16533813 |doi= 10.1074/jbc.M508651200 }}
*{{cite journal  | author=Michelotti GA, Brinkley DM, Morris DP, ''et al.'' |title=Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. |journal=FASEB J. |volume=21 |issue= 9 |pages= 1979-93 |year= 2007 |pmid= 17384146 |doi= 10.1096/fj.06-7118com }}
}}
{{refend}}
{{refend}}


{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:Adrenergic receptors‎]]
[[Category:G protein coupled receptors]]


{{WH}}
[[Category:Adrenergic receptors]]
{{WS}}
 
 
{{transmembranereceptor-stub}}

Latest revision as of 00:41, 27 October 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

The alpha-1D adrenergic receptor1D adrenoreceptor), also known as ADRA1D, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.[1]

Receptor

There are 3 alpha-1 adrenergic receptor subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. They activate mitogenic responses and regulate growth and proliferation of many cells.

Gene

This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.[1]

Ligands

Antagonists

See also

References

  1. 1.0 1.1 "Entrez Gene: ADRA1D adrenergic, alpha-1D-, receptor".
  2. Buckner SA, Milicic I, Daza A, Lynch JJ, Kolasa T, Nakane M, Sullivan JP, Brioni JD (2001). "A-315456: a selective alpha(1D)-adrenoceptor antagonist with minimal dopamine D(2) and 5-HT(1A) receptor affinity". Eur. J. Pharmacol. 433 (1): 123–7. doi:10.1016/s0014-2999(01)01519-9. PMID 11755142.
  3. Cleary L, Murad K, Bexis S, Docherty JR (2005). "The alpha (1D)-adrenoceptor antagonist BMY 7378 is also an alpha (2C)-adrenoceptor antagonist". Auton Autacoid Pharmacol. 25 (4): 135–41. doi:10.1111/j.1474-8673.2005.00342.x. PMID 16176444.

External links

Further reading

  • Schwinn DA, Lomasney JW (1992). "Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype". Eur. J. Pharmacol. 227 (4): 433–6. doi:10.1016/0922-4106(92)90162-O. PMID 1359975.
  • Bruno JF, Whittaker J, Song JF, Berelowitz M (1991). "Molecular cloning and sequencing of a cDNA encoding a human alpha 1A adrenergic receptor". Biochem. Biophys. Res. Commun. 179 (3): 1485–90. doi:10.1016/0006-291X(91)91740-4. PMID 1656955.
  • Esbenshade TA, Hirasawa A, Tsujimoto G, et al. (1995). "Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells". Mol. Pharmacol. 47 (5): 977–85. PMID 7746284.
  • Schwinn DA, Johnston GI, Page SO, et al. (1995). "Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues". J. Pharmacol. Exp. Ther. 272 (1): 134–42. PMID 7815325.
  • Weinberg DH, Trivedi P, Tan CP, et al. (1994). "Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c". Biochem. Biophys. Res. Commun. 201 (3): 1296–304. doi:10.1006/bbrc.1994.1845. PMID 8024574.
  • Loftus SK, Shiang R, Warrington JA, et al. (1994). "Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5". Cytogenet. Cell Genet. 67 (2): 69–74. doi:10.1159/000133802. PMID 8039425.
  • Yang-Feng TL, Han H, Lomasney JW, Caron MG (1994). "Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13". Cytogenet. Cell Genet. 66 (3): 170–1. doi:10.1159/000133693. PMID 8125015.
  • Forray C, Bard JA, Wetzel JM, et al. (1994). "The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype". Mol. Pharmacol. 45 (4): 703–8. PMID 8183249.
  • Minneman KP, Lee D, Zhong H, et al. (2000). "Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: comparison of alpha(1)-adrenergic receptor subtypes". J. Neurochem. 74 (6): 2392–400. doi:10.1046/j.1471-4159.2000.0742392.x. PMID 10820200.
  • Keffel S, Alexandrov A, Goepel M, Michel MC (2000). "alpha(1)-adrenoceptor subtypes differentially couple to growth promotion and inhibition in Chinese hamster ovary cells". Biochem. Biophys. Res. Commun. 272 (3): 906–11. doi:10.1006/bbrc.2000.2850. PMID 10860850.
  • Kyprianou N, Benning CM (2000). "Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis". Cancer Res. 60 (16): 4550–5. PMID 10969806.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
  • Shibata K, Katsuma S, Koshimizu T, et al. (2003). "alpha 1-Adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1". J. Biol. Chem. 278 (1): 672–8. doi:10.1074/jbc.M201375200. PMID 12409310.
  • Pupo AS, Minneman KP (2004). "Specific interactions between gC1qR and alpha1-adrenoceptor subtypes". J. Recept. Signal Transduct. Res. 23 (2–3): 185–95. doi:10.1081/RRS-120025200. PMID 14626446.
  • Hague C, Uberti MA, Chen Z, et al. (2004). "Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors". J. Biol. Chem. 279 (15): 15541–9. doi:10.1074/jbc.M314014200. PMID 14736874.
  • Gonzalez-Cabrera PJ, Shi T, Yun J, et al. (2004). "Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes". Endocrinology. 145 (11): 5157–67. doi:10.1210/en.2004-0728. PMID 15297446.
  • Zhang T, Xu Q, Chen FR, et al. (2005). "Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors". Acta Pharmacol. Sin. 25 (11): 1471–8. PMID 15525470.
  • Sigala S, Dellabella M, Milanese G, et al. (2005). "Evidence for the presence of alpha1 adrenoceptor subtypes in the human ureter". Neurourol. Urodyn. 24 (2): 142–8. doi:10.1002/nau.20097. PMID 15690361.
  • Chen Z, Hague C, Hall RA, Minneman KP (2006). "Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction". J. Biol. Chem. 281 (18): 12414–20. doi:10.1074/jbc.M508651200. PMID 16533813.
  • Michelotti GA, Brinkley DM, Morris DP, et al. (2007). "Epigenetic regulation of human α1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation". FASEB J. 21 (9): 1979–93. doi:10.1096/fj.06-7118com. PMC 2279228. PMID 17384146.