Mcm1 regulatory factor gene transcriptions

Associate Editor(s)-in-Chief: Henry A. Hoff

Human genes

Interactions

Consensus sequences

Consensus sequences: 1N2N3(A/C/T)4(A/C/T)5N6C7(C/T)8(A/C/T)9(A/C/T)10(A/T)11(A/C/T)12(A/C/T)13N14(A/G)15(C/G/T)16(A/C/T)17N18N19N.^[1]

The primary consensus sequence is apparently TT(A/T)CCNN(A/T)TNGG(A/T)AA.^[1]

Samplings

Copying a consensus regulatory element: TT(A/T)CCNN(A/T)TNGG(A/T)AA and putting the sequence in "⌘F" finds no locations for this sequence in any A1BG direction as can be found by the computer programs.

For the Basic programs testing consensus sequence TT(A/T)CCNN(A/T)TNGG(A/T)AA (starting with SuccessablesMcm.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
positive strand, negative direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
positive strand, positive direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
negative strand, positive direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
complement, negative strand, negative direction, looking for AA(A/T)GGNN(A/T)ANCC(A/T)TT, 0.
complement, positive strand, negative direction, looking for AA(A/T)GGNN(A/T)ANCC(A/T)TT, 0.
complement, positive strand, positive direction, looking for AA(A/T)GGNN(A/T)ANCC(A/T)TT, 0.
complement, negative strand, positive direction, looking for AA(A/T)GGNN(A/T)ANCC(A/T)TT, 0.
inverse complement, negative strand, negative direction, looking for TT(A/T)CCNA(A/T)NNGG(A/T)AA, 0.
inverse complement, positive strand, negative direction, looking for TT(A/T)CCNA(A/T)NNGG(A/T)AA, 0.
inverse complement, positive strand, positive direction, looking for TT(A/T)CCNA(A/T)NNGG(A/T)AA, 0.
inverse complement, negative strand, positive direction, looking for TT(A/T)CCNA(A/T)NNGG(A/T)AA, 0.
inverse negative strand, negative direction, looking for AA(A/T)GGNT(A/T)NNCC(A/T)TT, 0.
inverse positive strand, negative direction, looking for AA(A/T)GGNT(A/T)NNCC(A/T)TT, 0.
inverse positive strand, positive direction, looking for AA(A/T)GGNT(A/T)NNCC(A/T)TT, 0.
inverse negative strand, positive direction, looking for AA(A/T)GGNT(A/T)NNCC(A/T)TT, 0.

References

↑ ^1.0 ^1.1 Matthew J. Rossi, William K.M. Lai and B. Franklin Pugh (21 March 2018). "Genome-wide determinants of sequence-specific DNA binding of general regulatory factors". Genome Research. 28: 497–508. doi:10.1101/gr.229518.117. PMID 29563167. Retrieved 31 August 2020.

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