A1BG response element positive results
Associate Editor(s)-in-Chief: Henry A. Hoff
Def. nucleotide "sequences, usually upstream, which are recognized by specific regulatory transcription factors, thereby causing gene response to various regulatory agents", [that] "may be found in both promoter and enhancer regions"[1] are called response elements.
Hypotheses
- A1BG has all response elements in both promoters.
- A1BG is transcribed by all response elements.
- Each response element participates in the transcription of A1BG.
Response element positive results
Name of elements | Consensus sequences | Core promoters | Proximal promoters | Distal promoters |
---|---|---|---|---|
ABA responsive element (ABRE) | ACGTG(G/T)C | Positive strand, positive direction: 5'-ACGTGGC-3' at 4344 and complement | Positive strand, negative direction: 5'-ACGTGGC-3' at 4239 and complement | Negative strand, negative direction: 5'-CTGTGCA-3' at 3429 and complement
Positive strand, positive direction: 5'-GACACGT-3' at 2960, 5'-ACGTGTC-3' at 1823 and complements |
Abf1 regulatory factor | CGTNNNNN(A/G)(C/T)GA(C/T) | - | - | Positive strand, negative direction: 5'-CGTTCTTTATGAT-3' at 352 and complement
Positive strand, positive direction: 5'-CGTCACCGGTGAC-3' at 2073, 5'-CGTTCGGTGTGAC-3' at 346 and complements |
A box | TACGTA | - | Negative strand, negative direction: 5'-TACGTA-3' at 4246 and complement | Positive strand, positive direction: 5'-TACGTA-3' at 3071 and complement |
Box A | TGACTCT | - | - | Positive strand, negative direction: 5'-TGACTCT-3' at 2788 and complement
Positive strand, positive direction: 5'-TCTCAGT-3' at 2613 and complement |
Abscisic acid-responsive element | CACGTG | - | - | Negative strand, positive direction: 5'-CACGTG-3' at 570 and complement
Positive strand, positive direction: 5'-CACGTG-3' at 3884, 5'-CACGTG-3' at 2961, 5'-CACGTG-3' at 1219, and 5'-CACGTG-3' at 547 and complements |
Pho4p | CAC(A/G)T(T/G) | Positive strand, negative direction: 5'-CACATT-3' at 4533 and complement | - | Negative strand, negative direction: 5'-TTACAC-3' at 4091, 5'-AACGTG-3' at 3288, 3'-CACGTT-5' at 2864, 3'-CACATT-5' at 2087, 5'-TTACAC-3' at 2064, 5'-AACGTG-3' at 1718, 3'-CACGTT-5' at 1536, 5'-AACGTG-3' at 1346, 5'-AACGTG-3' at 1338, 3'-CACATG-5' at 797, 3'-CACATT-5' at 612, and 3'-CACATG-5' at 324 and complements
Positive strand, negative direction: 5'-CACATG-3' at 2667, 5'-CACGTT-3' at 343 and complements Negative strand, positive direction: 5'-CATGTG-3' at 3958, 5'-CACATG-3' at 3956, 5'-CATGTG-3' at 3902, 5'-CACATG-3' at 3742, 5'-CACATG-3' at 3707, 5'-CACATG-3' at 2031, 5'-CACGTG-3' at 570, 5'-AATGTG-3' at 229 and complements Positive strand, positive direction: 5'-CACGTG-3' at 3884, 5'-CACGTG-3' at 2961, 5'-CACGTT-3' at 2801, 5'-CACGTT-3' at 2335, 5'-CACGTG-3' at 1219, 5'-CACGTG-3' at 547 and complements |
H and ACA box | AGAGGA | Positive strand, negative direction: 5'-AGGACA-3' at 4468 and complements | Negative strand, positive direction: 3'-AGGACA-3' at 4252 and complements | Negative strand, negative direction: 5'-AGGACA-3' at 1911 and complements
Negative strand, positive direction: 5'-ACAGGA-3' at 3572, 3'-AGGACA-3' at 3131, 3'-AGGACA-3' at 2460 and complements Positive strand, negative direction: 5'-AGGACA-3' at 3756, 5'-AGGACA-3' at 3389, 5'-ACAGGA-3' at 2690 and complements Positive strand, positive direction: 5'-AGGACA-3' at 3622, 5'-ACAGGA-3' at 3620, 5'-AGGACA-3' at 144 and complements |
ACGT-containing element | ACGT | Negative strand, positive direction: 5'-TGCAC-3' at 4342 and complement | Negative strand, negative direction: 5'-ACGTG-3' at 4339 and complement
Positive strand, negative direction: 5'-ACGTG-3' at 4237 and complement |
Negative strand, negative direction: 5'-CACGT-3' at 3429, 5'-ACGTG-3' at 3288, 5'-CACGT-3' at 2863, 5'-ACGTG-3' at 2760, 5'-ACGTG-3' at 2425, 5'-CACGT-3' at 2081, 5'-ACGTG-3' at 1999, 5'-ACGTG-3' at 1718, 5'-CACGT-3' at 1535, 5'-CACGT-3' at 1470, 5'-ACGTG-3' at 1346, 5'-ACGTG-3' at 1338 and complements
Negative strand, positive direction: 5'-CACGT-3' at 3254, 5'-ACGTG-3' at 570, 5'-CACGT-3' at 569, and complements Positive strand, negative direction: 5'-CACGT-3' at 1772, 5'-CACGT-3' at 531, 5'-CACGT-3' at 342, and complements Positive strand, positive direction: 5'-CACGT-3' at 3960, 5'-ACGTG-3' at 3884, 5'-CACGT-3' at 3883, 5'-CACGT-3' at 3464, 5'-ACGTG-3' at 3342, 5'-ACGTG-3' at 3321, 5'-ACGTG-3' at 2961, 5'-CACGT-3' at 2960, 5'-CACGT-3' at 2800, 5'-CACGT-3' at 2681, 5'-CACGT-3' at 2334, 5'-CACGT-3' at 2326, 5'-CACGT-3' at 2063, 5'-ACGTG-3' at 1821, 5'-CACGT-3' at 1786, 5'-ACGTG-3' at 1471, 5'-ACGTG-3' at 1371, 5'-ACGTG-3' at 1219, 5'-CACGT-3' at 1218, 5'-CACGT-3' at 783, 5'-ACGTG-3' at 547, 5'-CACGT-3' at 546, and complements |
Activating protein 2 (Murata) | (C/G)CCN(3,4)GG(C/G) | Negative strand, positive direction: 5'-CCCTGGGGC-3' at 4427, 5'-CCCTTGGGG-3' at 4302 and complement | Negative strand, positive direction: 5'-CCCATGGGG-3' at 4224, 5'-CCCCATGGG-3' at 4223, and complements | Negative strand, negative direction: 5'-CCCTGCGGC-3' at 1154 and complement
Negative strand, positive direction: 5'-GCCCTGGGC-3' at 3498, 5'-GCCAATGGG-3' at 2911, 5'-GCCTCTGGC-3' at 2884, 5'-CCCTTAGGG-3' at 2766, 5'-GCCACCGGC-3' at 1547, 5'-GCCACCGGC-3' at 1295, 5'-GCCAGCGGC-3' at 332, 5'-CCCTCAGGC-3' at 91, and complements Positive strand, negative direction: 5'-CCCAAGGGC-3' at 1820 and complement Positive strand, positive direction: 5'-CCCGTTGGC-3' at 3912, 5'-CCCTGTGGG-3' at 3533, 5'-GCCAACGGG-3' at 3493, 5'-CCCAGAGGC-3' at 1961, 5'-GCCGGTGGG-3' at 1852, 5'-GCCCGCGGG-3' at 1770, 5'-CCCGGCGGC-3' at 1758, 5'-GCCCCCGGC-3' at 1647, 5'-CCCGACGGC-3' at 483, 5'-CCCTCCGGG-3' at 372, and complements |
Activating protein 2 (Cohen) | GCCTGGCC | - | - | Negative strand, negative direction: 5'-CCGGTCCG-3' at 4103, 5'-CGGACCGG-3' at 3130, 5'-CCGGTCCG-3' at 2520, 5'-CGGACCGG-3' at 1200, 5'-CCGGTCCG-3' at 649 and complements
Negative strand, positive direction: 5'-GCCTGGCC-3' at 3681, 5'-GCCTGGCC-3' at 2990, 5'-GGCCAGGC-3' at 1176 and complements |
Activating protein 2 (Cohen) | TCCCCCGCCC | - | - | Positive strand, positive direction: 5'-TCCCCCGCCC-3' at 4440 and complement |
Activating protein 2 (Yao) | TCTTCCC | - | Positive strand, positive direction: 5'-CCCTTCT-3' at 4264 and complement | Negative strand, negative direction: 5'-TCTTCCC-3' at 1657, 5'-GGGAAGA-3' at 620 and complements |
Activating protein 2 (Yao) | CTCCCA | Negative strand, negative direction: 5'-ACCCTC-3' at 4549, 5'-ACCCTC-3' at 4497 and complements | Negative strand, negative direction: 5'-ACCCTC-3' at 4303, 5'-ACCCTC-3' at 4271, 5'-GAGGGT-3' at 4259, 5'-ACCCTC-3' at 4153 and complements | Negative strand, negative direction: 5'-ACCCTC-3' at 3989, 5'-ACCCTC-3' at 3752, 5'-ACCCTC-3' at 3714, 5'-ACCCTC-3' at 3080, 5'-ACCCTC-3' at 2221, 5'-ACCCTC-3' at 2104, 5'-ACCCTC-3' at 1962, 5'-ACCCTC-3' at 1930, 5'-ACCCTC-3' at 1795, 5'-ACCCTC-3' at 1018, 5'-ACCCTC-3' at 686, 5'-ACCCTC-3' at 550, 5'-ACCCTC-3' at 413, 5'-GAGGGT-3' at 389 and complements.
Negative strand, positive direction: 5'-CTCCCA-3' at 3333, 5'-CTCCCA-3' at 2532, 5'-CTCCCA-3' at 2396, 5'-CTCCCA-3' at 2383, 5'-TGGGAG-3' at 1782, 5'-CTCCCA-3' at 466 and complements. Positive strand, positive direction: 5'-CTCCCA-3' at 3880, 5'-CTCCCA-3' at 2797, 5'-CTCCCA-3' at 182 |
Activating transcription factor (Burton) | (A/C/G)TT(A/G/T)C(A/G)TCA | - | - | Positive strand, negative direction: 5'-ATTTCATCA-3' at 2888, 5'-TGACGAAAC-3' at 313 and complement
Negative strand, positive direction: 5'-CTTGCGTCA-3' at 2423, 5'-TGACGTAAG-3' at 2207, 5'-TGATGAAAC-3' at 2147, 5'-CTTTCGTCA-3' at 1184 and complements |
Activating transcription factor (Kilberg) | (A/G/T)TT(A/G/T)CATCA | - | - | Positive strand, negative direction: 5'-ATTTCATCA-3' at 2888 and complement
Negative strand, positive direction: 5'-TGATGAAAC-3' at 2147 and complement |
Adr1p | TTGG(A/G)G | Negative strand, positive direction: 5'-TTGGGG-3' at 4302, and complement | - | Negative strand, negative direction: 5'-CCCCAA-3' at 3803, 5'-TTGGAG-3' at 3786, 5'-CTCCAA-3' at 3260, 5'-TTGGGG-3' at 3150, 5'-AACCTC-3' at 3118, 5'-AACCCC-3' at 2923, 5'-TTGGGG-3' at 2623, 5'-CTCCAA-3' at 2397, 5'-TTGGGG-3' at 2286, 5'-TTGGGG-3' at 1859, 5'-CTCCAA-3' at 1318, 5'-TTGGGG-3' at 1216, 5'-CTCCAA-3' at 1027, 5'-CTCCAA-3' at 861, 5'-TTGGGG-3' at 616, and complements.
Positive strand, negative direction: 5'-TTGGAG-3' at 3118, 5'-TTGGGG-3' at 2923, and complements Negative strand, positive direction: 5'-TTGGGG-3' at 2285, 5'-CTCCAA-3' at 1278, 5'-CTCCAA-3' at 942, 5'-CTCCAA-3' at 842, 5'-CTCCAA-3' at 606, 5'-CCCCAA-3' at 176, and complements Positive strand, positive direction: 5'-TTGGGG-3' at 3939, 5'-CTCCAA-3' at 1925, 5'-TTGGAG-3' at 1618, 5'-TTGGAG-3' at 610, 5'-CTCCAA-3' at 304, and complements |
Aft1 | (C/T)(A/G)CACCC(A/G) | - | - | Negative strand, negative direction: 5'-TGGGTGTG-3' at 1804, and complement
Positive strand, negative direction: 5'-TGGGTGTG-3' at 3185, 5'-CGGGTGCG-3' at 2196, 5'-CGGGTGCG-3' at 379, and complements Negative strand, positive direction: 5'-TGCACCCG-3' at 3324 and complement |
Acknowledgements
The content on this page was first contributed by: Henry A. Hoff.
See also
References
- ↑ MeSH (8 July 2008). "Response Elements". U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894: National Institutes of Health, Health & Human Services. Retrieved 2 September 2020.