Cyclobarbital: Difference between revisions

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{{Drugbox|
{{Drugbox
|IUPAC_name = ''5-(1-cyclohexenyl)-5-ethyl-1,3-diazinane-2,4,6-trione''
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 460109682
| IUPAC_name = ''5-(1-cyclohexenyl)-5-ethyl-1,3-diazinane-2,4,6-trione''
| image = Cyclobarbital.svg
| image = Cyclobarbital.svg
| width=100
| width = 100
| CAS_number=52-31-3
| image2 = Cyclobarbital ball-and-stick.png
| ATC_prefix=N05
| width2 = 180
| ATC_suffix=CA10
 
| ATC_supplemental=
<!--Clinical data-->
| PubChem=5838
| Drugs.com = {{Drugs.com|international|cyclobarbital}}
| DrugBank=
| tradename =
| C=12 | H=16 | N=2 | O=3
| pregnancy_category =  
| molecular_weight = 236.267
| legal_status =  
| bioavailability= ?
| routes_of_administration = Oral
 
<!--Pharmacokinetic data-->
| bioavailability =  
| metabolism = [[Hepatic]]
| metabolism = [[Hepatic]]
| elimination_half-life= ?
| elimination_half-life =  
| excretion = [[Renal]]
| excretion = [[Renal]]
| pregnancy_category = ?
 
| legal_status = ?
<!--Identifiers-->
| routes_of_administration= Oral
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 143-76-0
| ATC_prefix = N05
| ATC_suffix = CA10
| PubChem = 5838
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 5632
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 0M8A98AD9H
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D07323
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 268164
 
<!--Chemical data-->
| C=12 | H=16 | N=2 | O=3
| molecular_weight = 236.267 g/mol
| smiles = O=C1NC(=O)NC(=O)C1(/C2=C/CCCC2)CC
| InChI = 1/C12H16N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h6H,2-5,7H2,1H3,(H2,13,14,15,16,17)
| InChIKey = WTYGAUXICFETTC-UHFFFAOYAC
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C12H16N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h6H,2-5,7H2,1H3,(H2,13,14,15,16,17)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = WTYGAUXICFETTC-UHFFFAOYSA-N
}}
}}
'''Cyclobarbital''', also known as '''cyclobarbitol''' or '''cyclobarbitone''', is a [[drug]] which is a [[barbiturate]] [[derivative (chemistry)|derivative]].  
'''Cyclobarbital''', also known as '''cyclobarbitol''' or '''cyclobarbitone''', is a [[drug]] which is a [[barbiturate]] [[derivative (chemistry)|derivative]].<ref>{{cite pmid|989475}}</ref> It is primarily available in fixed-dose combination with [[diazepam]] under the brand name '''Reladorm''' (100 mg cyclobarbital + 10 mg diazepam) and is used to treat [[insomnia]] in Russia.
 
==References==
{{reflist}}
 


{{barbiturates}}
{{Hypnotics and sedatives}}
{{Hypnotics and sedatives}}
{{GABAAR PAMs}}
[[Category:Barbiturates]]
[[Category:Barbiturates]]
[[Category:Sedatives]]
[[Category:GABAA receptor positive allosteric modulators]]
 


{{pharma-stub}}


[[de:Cyclobarbital]]
{{sedative-stub}}
[[sv:Cyklobarbital]]

Revision as of 13:38, 13 April 2015

Cyclobarbital
File:Cyclobarbital.svg
File:Cyclobarbital ball-and-stick.png
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
Pharmacokinetic data
MetabolismHepatic
ExcretionRenal
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC12H16N2O3
Molar mass236.267 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Cyclobarbital, also known as cyclobarbitol or cyclobarbitone, is a drug which is a barbiturate derivative.[1] It is primarily available in fixed-dose combination with diazepam under the brand name Reladorm (100 mg cyclobarbital + 10 mg diazepam) and is used to treat insomnia in Russia.

References

  1. PMID 989475 (PMID 989475)
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Template:GABAAR PAMs


Template:Sedative-stub