Sterol response element gene transcriptions: Difference between revisions

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(Created page with "{{AE}} Henry A. Hoff "These genomic sequences were analysed for the presence of sterol-response elements (SRE) motif (5'-TCGTATA-3') [...] using the NCBI BLAST tool."<ref nam...")
 
 
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==Consensus sequences==
==Consensus sequences==


Consensus sequence for the sterol regulatory element is AGCAGATTGCG or CAGCAGATTGCG.<ref name=Yao2016/>
Consensus sequence for the sterol regulatory element is AGCAGATTGCG or CAGCAGATTGCG.<ref name=Yao2016>{{ cite journal
|author=D. W. Yao, J. Luo, Q. Y. He, J. Li, H. Wang, H. B. Shi, H. F. Xu, M. Wang and J. J. Loor
|title=Characterization of the liver X receptor-dependent regulatory mechanism of goat stearoyl-coenzyme A desaturase 1 gene by linoleic acid
|journal=Journal of Dairy Science
|date=May 2016
|volume=99
|issue=5
|pages=3945-3957
|url=https://www.sciencedirect.com/science/article/pii/S0022030216300273
|arxiv=
|bibcode=
|doi=10.3168/jds.2015-10601
|pmid=26947306
|accessdate=5 September 2020 }}</ref>


==Samplings==
==SRE (Branco) samplings==


Copying the SRE consensus: 5'-TCGTATA-3' and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.
Copying the SRE consensus: TCGTATA and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.


Copying the SRE consensus: 5'-CAGCAGATTGCG-3' and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.
For the Basic programs testing consensus sequence TCGTATA (starting with SuccessablesSREB.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
# negative strand, negative direction, looking for TCGTATA, 0.
# positive strand, negative direction, looking for TCGTATA, 0.
# positive strand, positive direction, looking for TCGTATA, 0.
# negative strand, positive direction, looking for TCGTATA, 0.
# complement, negative strand, negative direction, looking for AGCATAT, 0.
# complement, positive strand, negative direction, looking for AGCATAT, 0.
# complement, positive strand, positive direction, looking for AGCATAT, 0.
# complement, negative strand, positive direction, looking for AGCATAT, 0.
# inverse complement, negative strand, negative direction, looking for TATACGA, 0.
# inverse complement, positive strand, negative direction, looking for TATACGA, 0.
# inverse complement, positive strand, positive direction, looking for TATACGA, 0.
# inverse complement, negative strand, positive direction, looking for TATACGA, 0.
# inverse negative strand, negative direction, looking for ATATGCT, 0.
# inverse positive strand, negative direction, looking for ATATGCT, 0.
# inverse positive strand, positive direction, looking for ATATGCT, 0.
# inverse negative strand, positive direction, looking for ATATGCT, 0.
 
==SRE (Yao) samplings==
 
Copying the SRE consensus: NAGCAGATTGCG and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.
 
For the Basic programs testing consensus sequence NAGCAGATTGCG (starting with SuccessablesSREY.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
# negative strand, negative direction, looking for NAGCAGATTGCG, 0.
# positive strand, negative direction, looking for NAGCAGATTGCG, 0.
# positive strand, positive direction, looking for NAGCAGATTGCG, 0.
# negative strand, positive direction, looking for NAGCAGATTGCG, 0.
# complement, negative strand, negative direction, looking for NTCATCTAACGC, 0.
# complement, positive strand, negative direction, looking for NTCATCTAACGC, 0.
# complement, positive strand, positive direction, looking for NTCATCTAACGC, 0.
# complement, negative strand, positive direction, looking for NTCATCTAACGC, 0.
# inverse complement, negative strand, negative direction, looking for CGCAATCTACTN, 0.
# inverse complement, positive strand, negative direction, looking for CGCAATCTACTN, 0.
# inverse complement, positive strand, positive direction, looking for CGCAATCTACTN, 0.
# inverse complement, negative strand, positive direction, looking for CGCAATCTACTN, 0.
# inverse negative strand, negative direction, looking for GCGTTAGACGAN, 0.
# inverse positive strand, negative direction, looking for GCGTTAGACGAN, 0.
# inverse positive strand, positive direction, looking for GCGTTAGACGAN, 0.
# inverse negative strand, positive direction, looking for GCGTTAGACGAN, 0.
 
==Acknowledgements==
 
The content on this page was first contributed by: Henry A. Hoff.


==See also==
==See also==
{{div col|colwidth=20em}}
{{div col|colwidth=20em}}
* [[A1BG gene transcription core promoters]]
* [[A1BG gene transcriptions]]
* [[A1BG regulatory elements and regions]]
* [[A1BG response element gene transcriptions]]
* [[A1BG response element negative results]]
* [[A1BG response element positive results]]
* [[Complex locus A1BG and ZNF497]]
* [[Complex locus A1BG and ZNF497]]
* [[Transcription factor]]
{{Div col end}}
{{Div col end}}


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==External links==
==External links==
* [http://www.genome.jp/ GenomeNet KEGG database]
* [http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene Home - Gene - NCBI]
* [http://www.ncbi.nlm.nih.gov/sites/gquery NCBI All Databases Search]
* [http://www.ncbi.nlm.nih.gov/ncbisearch/ NCBI Site Search]
* [http://www.ncbi.nlm.nih.gov/pccompound PubChem Public Chemical Database]


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[[Category:Resources last modified in September 2020]]
[[Category:Resources last modified in February 2021]]

Latest revision as of 03:22, 1 March 2021

Associate Editor(s)-in-Chief: Henry A. Hoff

"These genomic sequences were analysed for the presence of sterol-response elements (SRE) motif (5'-TCGTATA-3') [...] using the NCBI BLAST tool."[1]

Human genes

Consensus sequences

Consensus sequence for the sterol regulatory element is AGCAGATTGCG or CAGCAGATTGCG.[2]

SRE (Branco) samplings

Copying the SRE consensus: TCGTATA and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence TCGTATA (starting with SuccessablesSREB.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

  1. negative strand, negative direction, looking for TCGTATA, 0.
  2. positive strand, negative direction, looking for TCGTATA, 0.
  3. positive strand, positive direction, looking for TCGTATA, 0.
  4. negative strand, positive direction, looking for TCGTATA, 0.
  5. complement, negative strand, negative direction, looking for AGCATAT, 0.
  6. complement, positive strand, negative direction, looking for AGCATAT, 0.
  7. complement, positive strand, positive direction, looking for AGCATAT, 0.
  8. complement, negative strand, positive direction, looking for AGCATAT, 0.
  9. inverse complement, negative strand, negative direction, looking for TATACGA, 0.
  10. inverse complement, positive strand, negative direction, looking for TATACGA, 0.
  11. inverse complement, positive strand, positive direction, looking for TATACGA, 0.
  12. inverse complement, negative strand, positive direction, looking for TATACGA, 0.
  13. inverse negative strand, negative direction, looking for ATATGCT, 0.
  14. inverse positive strand, negative direction, looking for ATATGCT, 0.
  15. inverse positive strand, positive direction, looking for ATATGCT, 0.
  16. inverse negative strand, positive direction, looking for ATATGCT, 0.

SRE (Yao) samplings

Copying the SRE consensus: NAGCAGATTGCG and putting the sequence in "⌘F" finds no location between ZNF497 and A1BG and no location between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence NAGCAGATTGCG (starting with SuccessablesSREY.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

  1. negative strand, negative direction, looking for NAGCAGATTGCG, 0.
  2. positive strand, negative direction, looking for NAGCAGATTGCG, 0.
  3. positive strand, positive direction, looking for NAGCAGATTGCG, 0.
  4. negative strand, positive direction, looking for NAGCAGATTGCG, 0.
  5. complement, negative strand, negative direction, looking for NTCATCTAACGC, 0.
  6. complement, positive strand, negative direction, looking for NTCATCTAACGC, 0.
  7. complement, positive strand, positive direction, looking for NTCATCTAACGC, 0.
  8. complement, negative strand, positive direction, looking for NTCATCTAACGC, 0.
  9. inverse complement, negative strand, negative direction, looking for CGCAATCTACTN, 0.
  10. inverse complement, positive strand, negative direction, looking for CGCAATCTACTN, 0.
  11. inverse complement, positive strand, positive direction, looking for CGCAATCTACTN, 0.
  12. inverse complement, negative strand, positive direction, looking for CGCAATCTACTN, 0.
  13. inverse negative strand, negative direction, looking for GCGTTAGACGAN, 0.
  14. inverse positive strand, negative direction, looking for GCGTTAGACGAN, 0.
  15. inverse positive strand, positive direction, looking for GCGTTAGACGAN, 0.
  16. inverse negative strand, positive direction, looking for GCGTTAGACGAN, 0.

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

See also

References

  1. J. Branco, M. Ola, R. M. Silva, E. Fonseca, N. C. Gomes, C. Martins-Cruz, A. P. Silva, A. Silva-Dias, C. Pina-Vaz, C. Erraught, L. Brennan, A. G. Rodrigues, G. Butler and I. M. Miranda (August 2017). "Impact of ERG3 mutations and expression of ergosterol genes controlled by UPC2 and NDT80 in Candida parapsilosis azole resistance". Clinical Microbiology and Infection. 23 (8): 575.e1–575.e8. doi:10.1016/j.cmi.2017.02.002. PMID 28196695. Retrieved 5 September 2020.
  2. D. W. Yao, J. Luo, Q. Y. He, J. Li, H. Wang, H. B. Shi, H. F. Xu, M. Wang and J. J. Loor (May 2016). "Characterization of the liver X receptor-dependent regulatory mechanism of goat stearoyl-coenzyme A desaturase 1 gene by linoleic acid". Journal of Dairy Science. 99 (5): 3945–3957. doi:10.3168/jds.2015-10601. PMID 26947306. Retrieved 5 September 2020.

External links