Anileridine

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Anileridine
Clinical data
AHFS/Drugs.comMonograph
Routes of
administration
Tablets, injection
ATC code
Legal status
Legal status
Pharmacokinetic data
Protein binding> 95%
MetabolismHepatic
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
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Chemical and physical data
FormulaC22H28N2O2
Molar mass352.47 g/mol
3D model (JSmol)
Melting point83 °C (181.4 °F)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s. It differs from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.

Anileridine is no longer manufactured in the US or Canada.[1]

Administration

As tablets or injection.[2]

Pharmacokinetics

Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[3] It is mostly metabolized by the liver.

References

  1. "Discontinued Prescription Drug Products". Canadian Pharmacists' Association. Retrieved 28 July 2008.
  2. "Pharmaceutical Information - LERITINE". RxMed. Retrieved 16 June 2010.
  3. "Anileridine Consumer Information". MedicineNet. Retrieved 28 July 2008.

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