Pericardial effusion

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Pericardial effusion
Pericardial effusion.
Image courtesy of RadsWiki
ICD-10 I30, I31.3
ICD-9 420
DiseasesDB 2128
eMedicine med/1786 
MeSH D010490

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For a more extensive discussion, see the chapter entitled diseases of the pericardium

Overview

Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial cavity. Because of the limited amount of space in the pericardial cavity, fluid accumulation will lead to an increased intrapericardial pressure and this can negatively affect heart function. When there is a pericardial effusion with enough pressure to adversely affect heart function, this is called cardiac tamponade. Pericardial effusion usually results from a disturbed equilibrium between the production and re-absorption of pericardial fluid, or from a structural abnormality that allows fluid to enter the pericardial cavity.

Normal levels of pericardial fluid are from 15 to 50 mL.

Differential Diagnosis

Serous

Blood

  • Acute Myocardial Infarction
  • Anticoagulants
  • Aortic rupture
  • Cardiac Catheter
  • Chemotherapeutics
  • Coagulotherapy
  • Heart surgery
  • Neoplasm
  • Perforation
  • Trauma
  • Uremia

Lymph or chylous

  • Benign obstruction of thoracic duct
  • Idiopathic
  • Neoplasm

Metastatic tumor

Miscellaneous

Infectious

Noninfectious

Hypersensitivity or autoimmunity related

  • Rheumatic fever
  • Collagen vascular disease
  • Drug-induced
  • Inflammatory disorders, such as lupus
  • Pericarditis

Types

It may be transudative (congestive heart failure, myxoedema, nephrotic syndrome), exudative (tuberculosis, spread from empyema) or haemorrhagic (trauma, rupture of aneuryms, malignant effusion).

Symptoms

Chest pain, pressure symptoms. A small effusion may have no symptoms.

Pericardial effusion is also present after a specific type of heart defect repair. An Atrial Septal Defect Secundum, or ASD, when repaired will most likely produce a pericardial effusion due to one of the methods of repair. One repair method of an ASD is to take a piece of the peridcardial tissue and use it as a patch for the hole in the atrial cavity.

Diagnosis

EKG

Pericardial Effusion


Chest X-Ray

Pericardial effusion


Pericardial effusion


Images shown below are courtesy of RadsWiki

Pericardial effusion Day of the admission


Pericardial effusion. The second day of treatment.


CT and MRI

Cross-sectional imaging by CT or MRI is very sensitive in the detection of generalized or loculated pericardial effusions. Some fluid in the pericardial sac contributes to the apparent thickness and should be considered normal. Commonly, free-flowing fluid accumulates first at the posterolateral aspect of the left ventricle, when the patient is imaged in the supine position.

Estimation of the amount of fluid is possible to a limited extent based on the overall thickness of the crescent of fluid. Compared to cardiac ultrasound, CT and MRI may be particularly helpful in detecting loculated effusions, owing to the wide field of view provided by these techniques. Hemorrhagic effusions can be differentiated from a transudate or an exudate based on signal characteristics (high signal on T1-weighted images) or density (high-density clot on CT). Pulsation artefacts may cause local areas of low signal in a hemorrhagic effusion. Effusions are often incidentally noted on CT scans obtained for other indications.

Pericardial thickening (thickness >4 mm) is difficult to differentiate from a small generalized effusion. Both entities will reveal a low signal/density line that is thicker than the normal pericardial thickness. In acute pericarditis, the pericardial lining can show intermediate signal intensity and may enhance after gadolinium administration.

CT

  • CT attenuation measurements also enable the initial characterization of pericardial fluid.
  • A fluid collection with attenuation close to that of water is likely to be a simple effusion.
  • Attenuation greater than that of water suggests malignancy, hemopericardium, purulent exudate, or effusion associated with hypothyroidism.
  • Pericardial effusions with low attenuation also have been reported in cases of chylopericardium.

Images shown below are courtesy of RadsWiki

CT: pericardial effusion


Pericardial effusion. Second day of the admission.


MRI

  • The appearance of pericardial fluid is different on SE and GRE cine MR images.
  • Nonhemorrhagic fluid has low signal intensity on T1-weighted SE images and high intensity on GRE cine images. Conversely, hemorrhagic effusion is characterized by high signal intensity on T1-weighted SE images and low intensity on GRE cine images.
  • When an effusion is secondary to malignancy, an irregularly thickened pericardium or pericardial nodularity may be depicted on MR images.

Cardiac Catheterization

Flouroscopic images show pericardial effusion:

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Treatment

Treatment depends on the underlying cause and the severity of the heart impairment. Pericardial effusion due to a viral infection usually goes away within a few weeks without treatment. Some pericardial effusions remain small and never need treatment. If the pericardial effusion is due to a condition such as lupus, treatment with anti-inflammatory medications may help. If the effusion is compromising heart function and causing cardiac tamponade, it will need to be drained, most commonly by a needle inserted through the chest wall and into the pericardial space. A drainage tube is often left in place for several days. In some cases, surgical drainage may be required by pericardiocentesis, in which a needle, and sometimes a catheter are used to drain excess fluid.

References


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