Pre-excitation syndrome

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Pre-excitation syndrome
Classification and external resources
ICD-10 I45.6
ICD-9 426.7, 426.81
DiseasesDB 32903
MeSH D011226

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Pre-excitation syndrome

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Pre-excitation syndrome is a condition where the the ventricles of the heart become depolarized too early, which leads to their partially premature contraction. Normally, the atria (chambers taking venous blood) and the ventriculi (chambers propulsing blood towards organs) are electrically isolated, and only electrical passage exists at "atrioventricular node". In all pre-excitation syndromes, there is at least one more conductive pathway is present. Physiologically, the electrical depolarization wave 'waits' in atrioventricular node to allow atria contract before ventriculi. However, there is no such property exists in abnormal pathway, so electrical stimulus passes to ventricule by this tracts far before normal atrioventricular-his system, and ventricules are depolarized (excitated) before (pre-) normal conduction system. The term pre-excitation derives from this condition.

It is usually caused by a secondary conduction pathway (other than the bundle of His):

Type Conduction pathway PR interval QRS interval Delta wave?
Wolff-Parkinson-White syndrome Bundle of Kent (atria to ventricles) short long yes
Lown-Ganong-Levine syndrome "James bundle" (atria to bundle of His) short normal no
Mahaim-type Mahaim fibers normal long yes

See also


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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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