Presumed ocular histoplasmosis syndrome

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Presumed ocular histoplasmosis syndrome
Classification and external resources
DiseasesDB 31279
eMedicine oph/406 

Presumed ocular histoplasmosis syndrome (POHS) is a disease syndrome affecting the eye that is characterized by peripheral atrophic chorioretinal scars, atrophy or scarring adjacent to the optic disc and maculopathy. It is thought to be caused by Histoplasma capsulatum, but the fungus has rarely been isolated from cases with POHS. The loss of vision in POHS is caused by choroidal neovascularisation. Fluorescein angiography is required for diagnosis and follow-up of patients with POHS. Treatment requires careful consideration of FA findings and few cases may respond to corticosteroids and laser photocoagulation. A vitreo-retinal specialist should be consulted for proper management of the case.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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