Scleritis
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| Scleritis Classification and external resources | |
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| Scleritis: Inflammation limited to the sclera. Note markedly dilated blood vessels which do not extend onto the underside of the lower lid, helping to distinguish scleritis from conjunctivitis. (Image courtesy of Charlie Goldberg, M.D.) | |
| ICD-10 | H15.0 |
| ICD-9 | 379.0 |
| DiseasesDB | 11898 |
| MedlinePlus | 001003 scleritis. MedlinePlus2 |
| eMedicine | emerg/521 oph/642 |
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Most recent articles on Scleritis | |
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Ongoing Trials on Scleritis at Clinical Trials.gov Clinical Trials on Scleritis at Google
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US National Guidelines Clearinghouse on Scleritis
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Patient resources on Scleritis Discussion groups on Scleritis Directions to Hospitals Treating Scleritis Risk calculators and risk factors for Scleritis
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Causes & Risk Factors for Scleritis | |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753
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Overview
Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera. The disease is often contracted through association with other diseases of the body, such as Wegener's granulomatosis or rheumatoid arthritis; it can also be attained through disorders of menstruation. For this reason, scleritis occurs frequently among young women. There are three types of scleritis: diffuse scleritis (the most common), nodular scleritis, and necrotizing scleritis (the most severe). Scleritis may be the first symptom of onset connective tissue disease[3].
The term "Episcleritis" refers to inflammation of the episclera.
Signs and symptoms
Symptoms of the disease include:
- Redness of the sclera and conjunctiva, sometimes changing to a purple hue
- Severe ocular pain (not present in episcleritis) which may radiate to the temple or jaw
- Increased light sensitivity and tearing
- Decrease in visual acuity, possibly leading to blindness
Diagnosis
Scleritis is best detected by examining the sclera in daylight; retracting the lids helps determine the extent of involvement. Other aspects of the eye exam (i.e. visual acuity testing, slit lamp examination, etc) can be normal. Ancillary tests CT scans, MRIs, and ultrasonographies can be helpful, but do not replace the physical examination.
Treatment
In very severe cases of necrotizing scleritis, eye surgery must be performed to repair damaged corneal tissue in the eye and preserve the patient's vision. For less severe cases, nonsteroidal anti-inflammatory drugs, such as ibuprofen, are prescribed for pain relief. Scleritis itself is treated with an oral medication containing corticosteroids and an eye solution. In some cases, antibiotics are prescribed. Simply using eye drops will not treat scleritis. If not treated, scleritis can cause blindness.
External links
References
- Sainz de la Maza, Maite, MD, PhD "Scleritis", eMedicine.com, September 26 2006. Accessed June 12 2007.
WikiDoc Research Resources for Scleritis | |
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| Articles on Scleritis | Most recent articles on Scleritis • Most cited articles on Scleritis • Review articles on Scleritis • Articles on Scleritis in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Scleritis | Powerpoint slides on Scleritis • Images of Scleritis • Photos of Scleritis • Podcasts & MP3s on Scleritis • Videos on Scleritis |
| Evidence Based Medicine Regarding Scleritis | Cochrane Collaboration on Scleritis • Bandolier on Scleritis • TRIP on Scleritis |
| Cost Effectiveness of Scleritis | Cost Effectiveness of Scleritis |
| Clinical Trials Involving Scleritis | Ongoing Trials on Scleritis at Clinical Trials.gov • Trial results on Scleritis • Clinical Trials on Scleritis at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Scleritis | US National Guidelines Clearinghouse on Scleritis • NICE Guidance on Scleritis • NHS PRODIGY Guidance • FDA on Scleritis • CDC on Scleritis |
| Textbook Information on Scleritis | Books and Textbook Information on Scleritis |
| Pharmacology Resources on Scleritis | Dosing of Scleritis • Drug interactions with Scleritis • Side effects of Scleritis • Allergic reactions to Scleritis • Overdose information on Scleritis • Carcinogenicity information on Scleritis • Scleritis in pregnancy • Pharmacokinetics of Scleritis • |
| Genetics, Pharmacogenomics, and Proteinomics of Scleritis | Genetics of Scleritis • Pharmacogenomics of Scleritis • Proteomics of Scleritis |
| Newstories on Scleritis | Scleritis in the news • Be alerted to news on Scleritis • News trends on Scleritis |
| Commentary on Scleritis | Blogs on Scleritis |
| Patient Resources on Scleritis | Patient resources on Scleritis • Discussion groups on Scleritis • Patient Handouts on Scleritis • Directions to Hospitals Treating Scleritis • Risk calculators and risk factors for Scleritis |
| Healthcare Provider Resources on Scleritis | Symptoms of Scleritis • Causes & Risk Factors for Scleritis • Diagnostic studies for Scleritis • Treatment of Scleritis |
| Continuing Medical Education (CME) Programs on Scleritis | CME Programs on Scleritis |
| International Resources on Scleritis | Scleritis en Espanol • Scleritis en Francais |
| Business Resources on Scleritis | Scleritis in the Marketplace • Patents on Scleritis |
| Informatics Resources on Scleritis | List of terms related to Scleritis |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
