Rupatadine: Difference between revisions

Rupatadine
Clinical data
Routes of; administration	Oral
ATC code	R06AX28 (WHO) ;
Pharmacokinetic data
Protein binding	99%
Metabolism	Hepatic, CYP-mediated
Elimination half-life	5.9 hours
Excretion	Fecal (60.9%) and renal (34.6%)
Identifiers
	IUPAC name 8-chloro-6,11-dihydro-11-(1-((5-methyl-3-pyridyl)methyl)-; 4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine;
CAS Number	158876-82-5;
PubChem CID	133017;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C26H26ClN3
Molar mass	415.958 g/mol

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Revision as of 18:58, 27 September 2011

Overview

Rupatadine is a new selective histamine H₁ receptor and platelet-activating factor (PAF) antagonist. Ruptatadine is marketed by Panacea-Biotech under the trade name Ralif. Ralif is approved for the treatment of allergic rhinitis.

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Product information

Template:SIB

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v t e Antihistamines (R06)
Aminoalkyl ethers	Bromazine/Bromodiphenhydramine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylamines	Brompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediamines	Chloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivatives	Alimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivatives	Buclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic use	Antazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical use	Bamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline • Azelastine
Other antiallergics	Emedastine • Epinastine • Ketotifen • Montelukast • Olopatadine

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Clinical data
Routes of administration	Oral
ATC code	R06AX28 (WHO)
Pharmacokinetic data
Protein binding	99%
Metabolism	Hepatic, CYP-mediated
Elimination half-life	5.9 hours
Excretion	Fecal (60.9%) and renal (34.6%)
Identifiers
IUPAC name 8-chloro-6,11-dihydro-11-(1-((5-methyl-3-pyridyl)methyl)- 4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
CAS Number	158876-82-5
PubChem CID	133017
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₆H₂₆ClN₃
Molar mass	415.958 g/mol

Rupatadine: Difference between revisions

Revision as of 18:58, 27 September 2011

Overview

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