Phenyltoloxamine

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Phenyltoloxamine
Phenyltoloxamine.png
Clinical data
Routes of
administration
oral
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC17H21NO
Molar mass255.359

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Overview

Phenyltoloxamine is an antihistamine with sedative and analgesic effects. It is a member of the ethanolamine class of antihistaminergic agents and a potent anticholinergic.

Common use

Phenyltoloxamine is widely used in preparations as an enhancing agent for some analgesics and antitussives (acetaminophen, codeine, hydrocodone). It is widely used in certain parts of the world as cough suppressant usually with codeine.

It also used to discourage abuse in certain opiate analgesics due its unpleasant side effects at high doses.

Adverse effects

Common adverse effects are those associated with most anticholinergics, effects are more pronounced in children and the elderly.

Availability

Phenyltoloxamine is available in most countries, though is rare in several western countries it remains widely used around the world, particularly in the developing world.

It is not a controlled substance; however some preparations contain opiates such as codeine or hydrocodone and are controlled, when used in preparations with acetaminophen is generally over the counter.

Phenyltoloxamine is sold under wide variety of preparations, brand names and dosages around the world:

  • Ed-Flex, Dologesic, Flextra-650, Novagesic, Phenylgesic - North America
  • Codipront - Europe/South America



Cost Effectiveness of Phenyltoloxamine

| group5 = Clinical Trials Involving Phenyltoloxamine | list5 = Ongoing Trials on Phenyltoloxamine at Clinical Trials.govTrial results on PhenyltoloxamineClinical Trials on Phenyltoloxamine at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Phenyltoloxamine | list6 = US National Guidelines Clearinghouse on PhenyltoloxamineNICE Guidance on PhenyltoloxamineNHS PRODIGY GuidanceFDA on PhenyltoloxamineCDC on Phenyltoloxamine


| group7 = Textbook Information on Phenyltoloxamine | list7 = Books and Textbook Information on Phenyltoloxamine


| group8 = Pharmacology Resources on Phenyltoloxamine | list8 = AND (Dose)}} Dosing of PhenyltoloxamineAND (drug interactions)}} Drug interactions with PhenyltoloxamineAND (side effects)}} Side effects of PhenyltoloxamineAND (Allergy)}} Allergic reactions to PhenyltoloxamineAND (overdose)}} Overdose information on PhenyltoloxamineAND (carcinogenicity)}} Carcinogenicity information on PhenyltoloxamineAND (pregnancy)}} Phenyltoloxamine in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Phenyltoloxamine


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Phenyltoloxamine | list9 = AND (pharmacogenomics)}} Genetics of PhenyltoloxamineAND (pharmacogenomics)}} Pharmacogenomics of PhenyltoloxamineAND (proteomics)}} Proteomics of Phenyltoloxamine


| group10 = Newstories on Phenyltoloxamine | list10 = Phenyltoloxamine in the newsBe alerted to news on PhenyltoloxamineNews trends on Phenyltoloxamine


| group11 = Commentary on Phenyltoloxamine | list11 = Blogs on Phenyltoloxamine

| group12 = Patient Resources on Phenyltoloxamine | list12 = Patient resources on PhenyltoloxamineDiscussion groups on PhenyltoloxaminePatient Handouts on PhenyltoloxamineDirections to Hospitals Treating PhenyltoloxamineRisk calculators and risk factors for Phenyltoloxamine


| group13 = Healthcare Provider Resources on Phenyltoloxamine | list13 = Symptoms of PhenyltoloxamineCauses & Risk Factors for PhenyltoloxamineDiagnostic studies for PhenyltoloxamineTreatment of Phenyltoloxamine

| group14 = Continuing Medical Education (CME) Programs on Phenyltoloxamine | list14 = CME Programs on Phenyltoloxamine

| group15 = International Resources on Phenyltoloxamine | list15 = Phenyltoloxamine en EspanolPhenyltoloxamine en Francais

| group16 = Business Resources on Phenyltoloxamine | list16 = Phenyltoloxamine in the MarketplacePatents on Phenyltoloxamine

| group17 = Informatics Resources on Phenyltoloxamine | list17 = List of terms related to Phenyltoloxamine


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