Oxatomide

Oxatomide

Gene therapy
Clinical data
Trade names	Tinset, Cedlips, Atoxan
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	R06AE06 (WHO)
Physiological data
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Identifiers
IUPAC name 1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2H-benzimidazol-2-one
CAS Number	60607-34-3 N
PubChem Template:Abbreviation	4615
ChemSpider	4454 Y
UNII	J31IL9Z2EE
KEGG	D01773 Y
ChEMBL	ChEMBL13828 Y
Chemical and physical data
Formula	C27H30N4O
Molar mass	426.553 g/mol
3D model (JSmol)	Interactive image
SMILES O=C2Nc1ccccc1N2CCCN5CCN(C(c3ccccc3)c4ccccc4)CC5
InChI InChI=1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32) Y Key:BAINIUMDFURPJM-UHFFFAOYSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Oxatomide (R35443) is a first-generation antihistamine of the phenylpiperazine class. It was discovered at Janssen Pharmaceutica in 1975. Oxatomide lacks any anticholinergic effects. In addition to its H₁ receptor antagonism, it also possesses antiserotonergic actions.

See also

• Piperazine