Lung mass differential diagnosis: Difference between revisions
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|- | |- | ||
! rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |Malignant | ! rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |Malignant | ||
! rowspan="3" style="background:#DCDCDC;" align="center" + |[[Squamous cell carcinoma of the lung|Squamous cell carcinoma | ! rowspan="3" style="background:#DCDCDC;" align="center" + |[[Squamous cell carcinoma of the lung|Squamous cell carcinoma (SCC)]]<ref name="pmid5528918">{{cite journal |vauthors=Roth E, Smidt D |title=[Studies on early ejaculate collection using electroejaculation in German improved land-swines and Goettinger miniature pigs] |language=German |journal=Berl. Munch. Tierarztl. Wochenschr. |volume=83 |issue=1 |pages=7–11 |date=January 1970 |pmid=5528918 |doi= |url=}}</ref> | ||
! colspan="2" style="background:#DCDCDC;" align="center" + |Papillary | ! colspan="2" style="background:#DCDCDC;" align="center" + |[[Papillary]] | ||
| rowspan="3" align="left" style="background:#F5F5F5;" + | | | rowspan="3" align="left" style="background:#F5F5F5;" + | | ||
* Cigarette | * [[Smoking|Cigarette smoking]] | ||
* [[Arsenic]] | * [[Arsenic]] | ||
| rowspan="3" align="left" style="background:#F5F5F5;" + | | | rowspan="3" align="left" style="background:#F5F5F5;" + | | ||
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* Central | * Central | ||
| rowspan="3" align="left" style="background:#F5F5F5;" + | | | rowspan="3" align="left" style="background:#F5F5F5;" + | | ||
* White or grey lesions | * White or grey [[Lesion|lesions]] | ||
* Focal carbon pigment deposits | * Focal carbon pigment deposits | ||
* [[Cavitation|Cavitations]] | * [[Cavitation|Cavitations]] | ||
* Intraluminal polypoid masses | * [[Lumen (anatomy)|Intraluminal]] polypoid masses | ||
* [[Infiltration (medical)|Infiltration]] | * [[Infiltration (medical)|Infiltration]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Exophytic | * Exophytic | ||
* Intra-epithelial | * Intra-[[Epithelium|epithelial]] | ||
* Without invasion | * Without [[Invasive (medical)|invasion]] | ||
| rowspan="3" align="left" style="background:#F5F5F5;" + | | | rowspan="3" align="left" style="background:#F5F5F5;" + | | ||
* [[Keratin]] | * [[Keratin]] | ||
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* [[Thyroid transcription factor-1]] ([[TTF-1]]) | * [[Thyroid transcription factor-1]] ([[TTF-1]]) | ||
| rowspan="3" align="left" style="background:#F5F5F5;" + | | | rowspan="3" align="left" style="background:#F5F5F5;" + | | ||
* Lobar or entire [[lung]] collapse | * [[Lobe (anatomy)|Lobar]] or entire [[lung]] collapse | ||
* Shift of the [[mediastinum]] to the ipsilateral side | * Shift of the [[mediastinum]] to the [[Anatomical terms of location|ipsilateral]] side | ||
* [[Hilum|Hilar]], perihilar or [[Mediastinal mass|mediastinal masses]] | * [[Hilum|Hilar]], perihilar or [[Mediastinal mass|mediastinal masses]] | ||
| rowspan="3" align="left" style="background:#F5F5F5;" + | | | rowspan="3" align="left" style="background:#F5F5F5;" + | | ||
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* [[Bone]] | * [[Bone]] | ||
|- | |- | ||
! colspan="2" style="background:#DCDCDC;" align="center" + |Clear cell | ! colspan="2" style="background:#DCDCDC;" align="center" + |[[Clear cell]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Cells with clear [[cytoplasm]] | * [[Cell (biology)|Cells]] with clear [[cytoplasm]] | ||
|- | |- | ||
! colspan="2" style="background:#DCDCDC;" align="center" + |Basaloid | ! colspan="2" style="background:#DCDCDC;" align="center" + |[[Basaloid large cell carcinoma of the lung|Basaloid]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Peripheral palisading of [[Cell nucleus|nuclei]] | * Peripheral palisading of [[Cell nucleus|nuclei]] | ||
* Poor differentiation | * Poor differentiation | ||
|- | |- | ||
! colspan="3" style="background:#DCDCDC;" align="center" + |'''[[Small cell carcinoma]]'''<ref name="pmid16226617">{{cite journal |vauthors=Jackman DM, Johnson BE |title=Small-cell lung cancer |journal=Lancet |volume=366 |issue=9494 |pages=1385–96 |date=2005 |pmid=16226617 |doi=10.1016/S0140-6736(05)67569-1 |url=}}</ref> | ! colspan="3" style="background:#DCDCDC;" align="center" + |'''[[Small cell lung cancer|Small cell carcinoma]]'''<ref name="pmid16226617">{{cite journal |vauthors=Jackman DM, Johnson BE |title=Small-cell lung cancer |journal=Lancet |volume=366 |issue=9494 |pages=1385–96 |date=2005 |pmid=16226617 |doi=10.1016/S0140-6736(05)67569-1 |url=}}</ref> | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* [[Smoking]] | * [[Smoking]] | ||
* [[Radon]] exposure | * [[Radon]] exposure | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Bronchial precursor cell | * [[Bronchial]] precursor [[Cell (biology)|cell]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Peripheral | * Peripheral | ||
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* White-tan, soft, friable perihilar masses | * White-tan, soft, friable perihilar masses | ||
* Extensive [[necrosis]] | * Extensive [[necrosis]] | ||
* 5% peripheral coin lesions | * 5% peripheral coin [[Lesion|lesions]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Sheet-like growth | * Sheet-like growth | ||
* Nesting | * Nesting | ||
* Trabeculae | * [[Trabecula|Trabeculae]] | ||
* Peripheral palisading | * Peripheral palisading | ||
* Rosette formation | * Rosette formation | ||
* High mitotic rate | * High [[Mitosis|mitotic]] rate | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* [[CD56]] | * [[CD56]] | ||
Line 255: | Line 255: | ||
* [[Hilum|Hilar]] or perihilar masses | * [[Hilum|Hilar]] or perihilar masses | ||
* [[Mediastinal lymphadenopathy]] | * [[Mediastinal lymphadenopathy]] | ||
* Lobar collapse | * [[Lobe (anatomy)|Lobar]] collapse | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* [[Bone marrow]] | * [[Bone marrow]] | ||
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! rowspan="10" style="background:#4479BA; color: #FFFFFF;" align="center" + |Malignant | ! rowspan="10" style="background:#4479BA; color: #FFFFFF;" align="center" + |Malignant | ||
! rowspan="10" style="background:#DCDCDC;" align="center" + |'''[[Adenocarcinoma]]'''<ref name="Kumar-adenocarcinoma">{{cite book |chapter=Chapter 13, box on morphology of adenocarcinoma |author=Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson |title=Robbins Basic Pathology|publisher=Saunders |location=Philadelphia |isbn=1-4160-2973-7 |edition=8th}}</ref><ref name="pmid17625570">{{cite journal| author=Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S et al.| title=Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. | journal=Nature | year= 2007 | volume= 448 | issue= 7153 | pages= 561-6 | pmid=17625570 | doi=10.1038/nature05945 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17625570 }}</ref><ref>Adenocarcinoma of the lung. Librepathology 2015. http://librepathology.org/wiki/index.php/File:Adenocarcinoma_%283950819000%29.jpg</ref> | ! rowspan="10" style="background:#DCDCDC;" align="center" + |'''[[Adenocarcinoma]]'''<ref name="Kumar-adenocarcinoma">{{cite book |chapter=Chapter 13, box on morphology of adenocarcinoma |author=Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson |title=Robbins Basic Pathology|publisher=Saunders |location=Philadelphia |isbn=1-4160-2973-7 |edition=8th}}</ref><ref name="pmid17625570">{{cite journal| author=Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S et al.| title=Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. | journal=Nature | year= 2007 | volume= 448 | issue= 7153 | pages= 561-6 | pmid=17625570 | doi=10.1038/nature05945 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17625570 }}</ref><ref>Adenocarcinoma of the lung. Librepathology 2015. http://librepathology.org/wiki/index.php/File:Adenocarcinoma_%283950819000%29.jpg</ref> | ||
! colspan="2" style="background:#DCDCDC;" align="center" + |'''Acinar adenocarcinoma''' | ! colspan="2" style="background:#DCDCDC;" align="center" + |'''[[Acinar adenocarcinoma of the lung|Acinar adenocarcinoma]]''' | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + | | | rowspan="10" align="left" style="background:#F5F5F5;" + | | ||
* [[Smoking]] | * [[Smoking]] | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + | | | rowspan="10" align="left" style="background:#F5F5F5;" + | | ||
* Columnar cells of bronchioles | * [[Columnar epithelia|Columnar cells]] of [[Bronchiole|bronchioles]] | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + | | | rowspan="10" align="left" style="background:#F5F5F5;" + | | ||
* Peripheral | * Peripheral | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + | | | rowspan="10" align="left" style="background:#F5F5F5;" + | | ||
* Single or multiple lesions | * Single or multiple [[Lesion|lesions]] | ||
* Different in size | * Different in size | ||
* Peripheral distribution | * Peripheral distribution | ||
* Gray-white central fibrosis | * Gray-white central [[fibrosis]] | ||
* [[Pleural]] puckering | * [[Pleural]] puckering | ||
* Anthracotic pigmentation | * Anthracotic pigmentation | ||
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** [[Cavitation]] | ** [[Cavitation]] | ||
** [[Hemorrhage]] | ** [[Hemorrhage]] | ||
* Lobulated or ill-defined edges | * [[Lobule|Lobulated]] or ill-defined edges | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Irregular-shaped glands | * Irregular-shaped [[Gland|glands]] | ||
* [[Malignant]] cells: | * [[Malignant]] [[Cell (biology)|cells]]: | ||
** Hyperchromatic [[Cell nucleus|nuclei]] | ** [[Hyperchromicity|Hyperchromatic]] [[Cell nucleus|nuclei]] | ||
** Fibroblastic stroma | ** [[Fibroblastic]] [[stroma]] | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + | | | rowspan="10" align="left" style="background:#F5F5F5;" + | | ||
* [[Epithelial|Epithelial markers]] | * [[Epithelial|Epithelial markers]] | ||
Line 303: | Line 303: | ||
* [[TTF-1]] | * [[TTF-1]] | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + | | | rowspan="10" align="left" style="background:#F5F5F5;" + | | ||
* Peripheral nodules under 4 | * Peripheral [[Nodule (medicine)|nodules]] under 4 cm in size | ||
* Central location as a [[Hilum|hilar]] or perihilar mass | * Central location as a [[Hilum|hilar]] or perihilar mass | ||
* Rarely show cavitations | * Rarely show cavitations | ||
* [[Hilar lymphadenopathy|Hilar adenopathy]] | * [[Hilar lymphadenopathy|Hilar adenopathy]] | ||
* [[Adenocarcinoma|Adenocarcinomas]] account for the majority of small peripheral cancers identified radiologically | * [[Adenocarcinoma|Adenocarcinomas]] account for the majority of small peripheral [[Cancer|cancers]] identified [[Radiology|radiologically]] | ||
| rowspan="10" align="left" style="background:#F5F5F5;" + |Aerogenous spread is characteristic | | rowspan="10" align="left" style="background:#F5F5F5;" + |Aerogenous spread is characteristic | ||
* [[Brain]] | * [[Brain]] | ||
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* [[Gastrointestinal tract]] | * [[Gastrointestinal tract]] | ||
|- | |- | ||
! colspan="2" style="background:#DCDCDC;" align="center" + |Papillary adenocarcinoma | ! colspan="2" style="background:#DCDCDC;" align="center" + |[[Papillary adenocarcinoma of the lung|Papillary adenocarcinoma]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* [[Papillae]] | * [[Papillae]] | ||
* [[Necrosis]] | * [[Necrosis]] | ||
* Surrounding invasion | * Surrounding [[Invasive (medical)|invasion]] | ||
* [[Cuboidal epithelia|Cuboidal]] to [[Columnar epithelia|columnar epithelial]] linning | * [[Cuboidal epithelia|Cuboidal]] to [[Columnar epithelia|columnar epithelial]] linning | ||
* [[Mucinous]] or non-mucinous | * [[Mucinous]] or non-mucinous | ||
|- | |- | ||
! rowspan="3" style="background:#DCDCDC;" align="center" + | | ! rowspan="3" style="background:#DCDCDC;" align="center" + |[[Bronchoalveolar carcinoma]] | ||
! style="background:#DCDCDC;" align="center" + |Non-mucinous | ! style="background:#DCDCDC;" align="center" + |Non-[[mucinous]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* [[Clara cell|Clara cells]] | * [[Clara cell|Clara cells]] | ||
* [[Pneumocytes|Type II cells]] | * [[Pneumocytes|Type II cells]] | ||
|- | |- | ||
! style="background:#DCDCDC;" align="center" + |Mucinous | ! style="background:#DCDCDC;" align="center" + |[[Mucinous]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Low grade differentiation | * Low grade differentiation | ||
* Composed of: | * Composed of: | ||
** Tall [[Columnar epithelia|columnar cells]] | ** Tall [[Columnar epithelia|columnar cells]] | ||
** Basal nuclei | ** Basal [[Cell nucleus|nuclei]] | ||
** Pale [[cytoplasm]] resembling goblet cells | ** Pale [[cytoplasm]] resembling [[Goblet cell|goblet cells]] | ||
** Varying amounts of cytoplasmic mucin | ** Varying amounts of [[Cytoplasm|cytoplasmic]] [[mucin]] | ||
* Cytologic [[atypia]] | * [[Cytological|Cytologic]] [[atypia]] | ||
|- | |- | ||
! style="background:#DCDCDC;" align="center" + |Mixed non-mucinous and mucinous or indeterminate | ! style="background:#DCDCDC;" align="center" + |Mixed non-[[mucinous]] and [[mucinous]] or indeterminate | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Mixed type of [[Cell (biology)|cells]] | * Mixed type of [[Cell (biology)|cells]] | ||
* Low to high grade differentiated [[Cell (biology)|cells]] | * Low to high grade differentiated [[Cell (biology)|cells]] | ||
|- | |- | ||
! rowspan="5" style="background:#DCDCDC;" align="center" + |Solid adenocarcinoma with mucin production | ! rowspan="5" style="background:#DCDCDC;" align="center" + |Solid [[adenocarcinoma]] with [[mucin]] production | ||
! style="background:#DCDCDC;" align="center" + |Fetal adenocarcinoma | ! style="background:#DCDCDC;" align="center" + |[[Fetal adenocarcinoma of the lung|Fetal adenocarcinoma]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Consists glandular elements: | * Consists [[Gland|glandular]] elements: | ||
** Tubules of [[glycogen]]-rich | ** [[Tubule|Tubules]] of [[glycogen]]-rich | ||
** Non-ciliated cells | ** Non-[[Cilium|ciliated]] [[Cell (biology)|cells]] | ||
** Subnuclear and supranuclear [[glycogen]] [[vacuoles]] | ** [[Nuclear|Subnuclear]] and [[Nuclear|supranuclear]] [[glycogen]] [[vacuoles]] | ||
** Rounded morules of polygonal cells with abundant [[eosinophilic]] and finely granular [[cytoplasm]] | ** Rounded morules of polygonal [[Cell (biology)|cells]] with abundant [[eosinophilic]] and finely [[Granule (cell biology)|granular]] [[cytoplasm]] | ||
|- | |- | ||
! style="background:#DCDCDC;" align="center" + |Mucinous (“colloid”) carcinoma | ! style="background:#DCDCDC;" align="center" + |[[Mucinous carcinoma|Mucinous (“colloid”) carcinoma]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Dissecting pools of [[mucin]] containing [[neoplastic]] cells | * Dissecting pools of [[mucin]] containing [[neoplastic]] [[Cell (biology)|cells]] | ||
|- | |- | ||
! style="background:#DCDCDC;" align="center" + |Mucinous cystadenocarcinoma | ! style="background:#DCDCDC;" align="center" + |[[Mucinous cystadenocarcinoma]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Partial [[fibrous tissue]] capsule | * Partial [[fibrous tissue]] capsule | ||
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* [[Neoplastic]] [[mucinous]] [[epithelium]] grows along [[Alveolus|alveolar]] walls | * [[Neoplastic]] [[mucinous]] [[epithelium]] grows along [[Alveolus|alveolar]] walls | ||
|- | |- | ||
! style="background:#DCDCDC;" align="center" + |Signet ring adenocarcinoma | ! style="background:#DCDCDC;" align="center" + |[[Signet ring cell carcinoma|Signet ring adenocarcinoma]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Focal | * Focal | ||
Line 370: | Line 370: | ||
* Components of other [[Cell (biology)|cells]] are present | * Components of other [[Cell (biology)|cells]] are present | ||
|- | |- | ||
! style="background:#DCDCDC;" align="center" + |Clear cell adenocarcinoma | ! style="background:#DCDCDC;" align="center" + |[[Clear cell carcinoma of the lung|Clear cell adenocarcinoma]] | ||
| align="left" style="background:#F5F5F5;" + | | | align="left" style="background:#F5F5F5;" + | | ||
* Clear [[Cell (biology)|cells]] with no [[Cell nucleus|nuclei]] | * Clear [[Cell (biology)|cells]] with no [[Cell nucleus|nuclei]] |
Revision as of 21:51, 13 June 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2], Eiman Ghaffarpasand, M.D. [3]
Overview
Lung mass can be differentiated from other conditions that cause chronic cough, hemoptysis, and weight loss based on the clinical features, laboratory findings, imaging features, histological features, and genetic studies.
Differentiating Lung Mass from other Diseases
- The table below summarizes the findings that differentiate lung mass based on the clinical features, laboratory findings, imaging features, histological features, and genetic studies.[1][2][3]
- Abrevations: HPV: human papillomavirus; CEA: Carcino embryogenic antigen; TTF1: Thyroid transcription factor-1; EMA: Epithelial membrane antigen; CK: Cytokeratin; CD: Cluster differentiation; NCAM: Neural cell adhesion molecule; MMPs: Matrix metalloproteinase; GFAP: Glial fibrillary acidic protein
Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
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Benign | Papilloma[4] | Squamous cell papilloma |
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Glandular papilloma |
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Adenoma[5] | Alveolar adenoma |
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Papillary adenoma[6] |
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Mucinous cystadenoma |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Squamous cell carcinoma (SCC)[7] | Papillary |
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Clear cell | |||||||||||
Basaloid |
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Small cell carcinoma[8] |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Adenocarcinoma[9][10][11] | Acinar adenocarcinoma |
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Aerogenous spread is characteristic | ||||||
Papillary adenocarcinoma | |||||||||||
Bronchoalveolar carcinoma | Non-mucinous | ||||||||||
Mucinous |
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Mixed non-mucinous and mucinous or indeterminate | |||||||||||
Solid adenocarcinoma with mucin production | Fetal adenocarcinoma |
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Mucinous (“colloid”) carcinoma |
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Mucinous cystadenocarcinoma |
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Signet ring adenocarcinoma | |||||||||||
Clear cell adenocarcinoma | |||||||||||
Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Large cell carcinoma[12] | Basaloid large cell carcinoma of the lung |
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Clear cell carcinoma of the lung | |||||||||||
Lymphoepithelioma-like carcinoma of the lung |
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Large-cell lung carcinoma with rhabdoid phenotype |
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Mixed type |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Sarcomatoid carcinoma[13] | Carcinosarcoma |
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Spindle cell carcinoma |
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Giant cell carcinoma |
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Pleomorphic carcinoma |
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Pulmonary blastoma |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Carcinoid tumor[14] | Typical carcinoid
Atypical carcinoid |
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Salivary gland tumors[15] | Mucoepidermoid carcinoma |
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Adenoid cystic carcinoma |
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Epithelial-myoepithelial carcinoma |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Preinvasive lesions[16] | Squamous carcinoma in situ |
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Atypical adenomatous hyperplasia |
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Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Mesenchymal tumors[17] | Epithelioid haemangioendothelioma / Angiosarcoma |
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Pleuropulmonary blastoma |
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Chondroma |
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Congenital peribronchial myofibroblastic tumor |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis | |
Malignant | Mesenchymal tumors[17] | Diffuse pulmonary lymphangiomatosis |
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Inflammatory myofibroblastic tumor |
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Pulmonary artery sarcoma |
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Pulmonary vein sarcoma |
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Type | Category | Disease | Epidemiology | Pleuripotent cells | Location | Gross pathology | Histology | Immunohistochemistry | Imaging | Metastasis |
References
- ↑ Erasmus JJ, Connolly JE, McAdams HP, Roggli VL (2000). "Solitary pulmonary nodules: Part I. Morphologic evaluation for differentiation of benign and malignant lesions". Radiographics. 20 (1): 43–58. doi:10.1148/radiographics.20.1.g00ja0343. PMID 10682770.
- ↑ Gümüştaş S, Inan N, Akansel G, Ciftçi E, Demirci A, Ozkara SK (June 2012). "Differentiation of malignant and benign lung lesions with diffusion-weighted MR imaging". Radiol Oncol. 46 (2): 106–13. doi:10.2478/v10019-012-0021-3. PMC 3472932. PMID 23077446.
- ↑ Kelley LC, Puette M, Langheinrich KA, King B (November 1994). "Bovine pulmonary blastomas: histomorphologic description and immunohistochemistry". Vet. Pathol. 31 (6): 658–62. doi:10.1177/030098589403100605. PMID 7863581.
- ↑ Maxwell RJ, Gibbons JR, O'Hara MD (January 1985). "Solitary squamous papilloma of the bronchus". Thorax. 40 (1): 68–71. PMC 459982. PMID 3969658.
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