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WikiDoc Resources for Atypia


Most recent articles on Atypia

Most cited articles on Atypia

Review articles on Atypia

Articles on Atypia in N Eng J Med, Lancet, BMJ


Powerpoint slides on Atypia

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Evidence Based Medicine

Cochrane Collaboration on Atypia

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Clinical Trials

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Trial results on Atypia

Clinical Trials on Atypia at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Atypia

NICE Guidance on Atypia


FDA on Atypia

CDC on Atypia


Books on Atypia


Atypia in the news

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Definitions of Atypia

Patient Resources / Community

Patient resources on Atypia

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Directions to Hospitals Treating Atypia

Risk calculators and risk factors for Atypia

Healthcare Provider Resources

Symptoms of Atypia

Causes & Risk Factors for Atypia

Diagnostic studies for Atypia

Treatment of Atypia

Continuing Medical Education (CME)

CME Programs on Atypia


Atypia en Espanol

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Atypia in the Marketplace

Patents on Atypia

Experimental / Informatics

List of terms related to Atypia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Atypia is a clinical term for abnormality in a cell. The term is medical jargon for an atypical cell. It may or may not be a precancerous indication associated with later malignancy, but the level of appropriate concern is highly dependent on the context with which it is diagnosed.

Atypia can be caused by an infection or irritation if diagnosed in a Pap smear, for example. In the uterus it is more likely to be precancerous.

The term atypia is also used dermatoligically and can be a precursor to melanoma.

A dermatological pathology report may show normal (junctional, compound, or intradermal) nevi, various levels of atypia (slight, moderate, severe), or melanoma. Atypia in this context is a precursor to melanoma, but is not yet melanoma.

If a mole shows slight or moderate atypia and margins are clear, no further treatment is typically needed. It would be wise to re-examine if pigmentation recurs after excision. If a mole shows slight or moderate atypia and margins are not clear, it is typical to re-excise or re-shave to get around the lesion.

If a mole shows marked or severe atypia or any degree of pathologist's concern for melanoma, it would be wise to seek professionals for further evaluation.