Leg pain

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Common Causes

Complete Differential Diagnosis of the causes of Leg pain

(By organ system)

Cardiovascular Aortoiliac occlusive disease,Cholesterol Emboli Syndrome,Deep Vein Thrombosis,Peripheral Arterial Disease,Thrombophlebitis,Varicose veins
Chemical / poisoning No underlying causes
Dermatologic Behect's disease
Drug Side Effect Abatacept Injection,Acebutolol,Acitretin,Aldesleukin,Alendronate,Allopurinol,Amikacin Sulfate Injection,Anagrelide,Anastrozole,Aripiprazole,Atazanavir,Atenolol,Atorvastatin,Bevacizumab Injection,Bortezomib,Buspirone,Capecitabine,Celecoxib,Celiac disease,Clofarabine Injection,Clonazepam,Clopidogrel,Cortisol,Darbepoetin Alfa,Docetaxel,Epoetin Alfa Injection,Ethacrynic Acid,Etidronate,Ezetimibe,Fenofibrate,Filgrastim,Fluvastatin,Gabapentin,Galantamine,Glatiramer Injection,Ibandronate,Iloprost,Imatinib,Infliximab Injection,Interferon Alfa-2a and Alfa-2b Injection,Interferon Alfacon-1 Injection,Interferon beta-1a Intramuscular Injection,Interferon Beta-1b Injection,Interferon Gamma-1b Injection,Lamivudine,Latanoprost,Leflunomide,Letrozole,Leuprolide,Lovastatin,Methimazole,Methylergonovine,Methylprednisolone,Mifepristone,Natalizumab injection ,Ofloxacin ,Paclitaxel,Peginterferon alfa-2a,Prednisone,Pyrazinamide,Quinupristin dalfopristin,Ribavirin,Rofecoxib,Rosiglitazone,Rosuvastatin,Sunitinib ,Tadalafil ,Tamsulosin ,Telbivudine ,Temozolomide ,Terbutaline,Teriparatide,Tiotropium,Torsemide,Valganciclovir,Valsartan,Vancomycin,Vinblastine,Vincristine,Zalcitabine,Ziprasidone,Zolmitriptan,Zolpidem,
Ear Nose Throat No underlying causes
Endocrine Hyperparathyroidism,Primary hyperparathyroidism
Environmental No underlying causes
Gastroenterologic Ulcerative colitis
Genetic Fairbanks disease,Familial Mediterranean fever,Mitochondrial trifunctional protein deficiency,Osteogenesis imperfecta,Hereditary multiple exostoses,Recessive multiple epiphyseal dysplasia,Farber disease
Hematologic Erdheim-Chester disease,Leukemia,Lymphangiomatosis,Multiple myeloma,Phlebitis,Phlegmasia cerulea dolens,Thrombocytosis,Acute lymphoblastic leukemia,Acute myeloid leukemia,Acute promyelocytic leukemia
Iatrogenic No underlying causes
Infectious Disease

Bacterial : Cellulitis,Q Fever,Lassa Fever,Lemierre's Syndrome

Viral : Parvovirus,Poliomyelitis,Rocky Mountain spotted fever,Acquired Immune Deficiency Syndrome

Musculoskeletal / Ortho Athlete's foot,Baker's cyst,Bone tumor,Buerger's disease,Chondroblastoma,Chondromalacia patellae,Chondrosarcoma,Gout,Hereditary multiple exostoses,Ledderhose's disease,Legg-Calve-Perthes syndrome,Morton's toe,Myofascial Pain Syndrome,Myositis ossificans,Osteochondrosis,Paget's disease of bone,Pes anserinus (leg),Pigmented villonodular synovitis,Prepatellar bursitis,Recessive multiple epiphyseal dysplasia,Retropatellar Pain Syndrome,Sciatica,Synovial osteochondromatosis,Tenosynovitis,Erythromelagia,Ewing's sarcoma,Giant cell tumor of bone,Osteoporosis,Still's disease,Fairbanks disease,Osteogenesis imperfecta
Neurologic Amyotrophic Lateral Sclerosis,Anterior spinal artery syndrome,Erythromelagia,Meralgia paraesthetica,Peripheral Neuropathy
Nutritional / Metabolic Acute Intermittent Porphyria,Farber disease,Glycogen storage disease type V,Hypercalcemia,Mucopolysaccharidosis,Osteomalacia
Obstetric/Gynecologic No underlying causes
Oncologic Acute lymphoblastic leukemia,Acute myeloid leukemia,Acute promyelocytic leukemia,Ewing's sarcoma,Giant cell tumor of bone,Osteochondroma,Osteoma,Osteosarcoma,Leukemia,Lymphangiomatosis,Chondroblastoma,Chondrosarcoma
Opthalmologic Behect's disease
Overdose / Toxicity No underlying causes
Psychiatric Pain disorder
Pulmonary No underlying causes
Renal / Electrolyte Hypercalcemia
Rheum / Immune / Allergy

Rheumatology : Ankylosing Spondylitis,Behect's disease,Caplan's Syndrome,Fibromyalgia,Osteoarthritis,Osteoporosis,Polymyalgia Rheumatica,Rheumatoid arthritis,Still's disease, Gout

Immunology : Systemic lupus erythematosus,Ulcerative colitis,Vasculitis,Graft-versus-host disease,Familial Mediterranean fever

Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Phantom pain


In alphabetical order: [1] [2]

References

  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

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