Portmanteau inhibitor

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A portmanteau inhibitor is a drug which is a combination of two drug molecules, each of which is itself a type of inhibitor. The term was coined in 2007 by University of Minnesota researchers who designed and synthesized a combination HIV Reverse transcriptase inhibitor and an Integrase inhibitor.[1][2][3]


  1. "U of M researchers announce advance in treatment of HIV". 25 July 2007. Unknown parameter |accessed-date= ignored (help)
  2. "Researchers Discover New Method To Combat HIV". 25 July 2007. Unknown parameter |accessed-date= ignored (help)
  3. Zhengqiang Wang, Eric M. Bennett, Daniel J. Wilson, Christine Salomon, and Robert Vince (2007). "Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and Integrase". Journal of Medicinal Chemistry. 50 (15): 3416-3419. PMID 17608468.