PCTK3: Difference between revisions

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{{Underlinked|date=August 2017}}
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{{Infobox_gene}}
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'''Serine/threonine-protein kinase PCTAIRE-3''' is an [[enzyme]] that in humans is encoded by the ''PCTK3'' [[gene]].<ref name="pmid1437147">{{cite journal |vauthors=Okuda T, Cleveland JL, Downing JR | title = PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family | journal = Oncogene | volume = 7 | issue = 11 | pages = 2249–58 |date=Dec 1992 | pmid = 1437147 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PCTK3 PCTAIRE protein kinase 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5129| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = PCTAIRE protein kinase 3
| HGNCid = 8751
| Symbol = PCTK3
| AltSymbols =; PCTAIRE; PCTAIRE3
| OMIM = 169190
| ECnumber =
| Homologene = 1949
| MGIid = 97518
  | GeneAtlas_image1 = PBB_GE_PCTK3_214797_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0004672 |text = protein kinase activity}} {{GNF_GO|id=GO:0004674 |text = protein serine/threonine kinase activity}} {{GNF_GO|id=GO:0004871 |text = signal transducer activity}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016740 |text = transferase activity}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}}
| Process = {{GNF_GO|id=GO:0006468 |text = protein amino acid phosphorylation}} {{GNF_GO|id=GO:0007165 |text = signal transduction}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5129
    | Hs_Ensembl = ENSG00000117266
    | Hs_RefseqProtein = NP_002587
    | Hs_RefseqmRNA = NM_002596
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 203740350
    | Hs_GenLoc_end = 203768544
    | Hs_Uniprot = Q07002
    | Mm_EntrezGene = 18557
    | Mm_Ensembl = ENSMUSG00000026437
    | Mm_RefseqmRNA = NM_008795
    | Mm_RefseqProtein = NP_032821
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 133941096
    | Mm_GenLoc_end = 133967174
    | Mm_Uniprot = Q0VDL5
  }}
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'''PCTAIRE protein kinase 3''', also known as '''PCTK3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PCTK3 PCTAIRE protein kinase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5129| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Okuda T, Cleveland JL, Downing JR |title=PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. |journal=Oncogene |volume=7 |issue= 11 |pages= 2249-58 |year= 1992 |pmid= 1437147 |doi=  }}
*{{cite journal   |vauthors=Meyerson M, Enders GH, Wu CL, etal |title=A family of human cdc2-related protein kinases. |journal=EMBO J. |volume=11 |issue= 8 |pages= 2909–17 |year= 1992 |pmid= 1639063 |doi= | pmc=556772 }}
*{{cite journal  | author=Meyerson M, Enders GH, Wu CL, ''et al.'' |title=A family of human cdc2-related protein kinases. |journal=EMBO J. |volume=11 |issue= 8 |pages= 2909-17 |year= 1992 |pmid= 1639063 |doi=  }}
*{{cite journal  |vauthors=Okuda T, Valentine VA, Shapiro DN, Downing JR |title=Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes. |journal=Genomics |volume=21 |issue= 1 |pages= 217–21 |year= 1994 |pmid= 8088790 |doi= 10.1006/geno.1994.1245 }}
*{{cite journal  | author=Okuda T, Valentine VA, Shapiro DN, Downing JR |title=Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes. |journal=Genomics |volume=21 |issue= 1 |pages= 217-21 |year= 1994 |pmid= 8088790 |doi= 10.1006/geno.1994.1245 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  |vauthors=Herskovits AZ, Davies P |title=Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain. |journal=Gene |volume=328 |issue=  |pages= 59–67 |year= 2004 |pmid= 15019984 |doi= 10.1016/j.gene.2003.12.011 }}
*{{cite journal  | author=Herskovits AZ, Davies P |title=Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain. |journal=Gene |volume=328 |issue=  |pages= 59-67 |year= 2004 |pmid= 15019984 |doi= 10.1016/j.gene.2003.12.011 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Palmer KJ, Konkel JE, Stephens DJ |title=PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport. |journal=J. Cell Sci. |volume=118 |issue= Pt 17 |pages= 3839–47 |year= 2005 |pmid= 16091426 |doi= 10.1242/jcs.02496 }}
*{{cite journal  | author=Palmer KJ, Konkel JE, Stephens DJ |title=PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport. |journal=J. Cell. Sci. |volume=118 |issue= Pt 17 |pages= 3839-47 |year= 2005 |pmid= 16091426 |doi= 10.1242/jcs.02496 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal  |vauthors=Herskovits AZ, Davies P |title=The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease. |journal=Neurobiol. Dis. |volume=23 |issue= 2 |pages= 398–408 |year= 2006 |pmid= 16766195 |doi= 10.1016/j.nbd.2006.04.004 }}
*{{cite journal  | author=Herskovits AZ, Davies P |title=The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease. |journal=Neurobiol. Dis. |volume=23 |issue= 2 |pages= 398-408 |year= 2006 |pmid= 16766195 |doi= 10.1016/j.nbd.2006.04.004 }}
*{{cite journal   |vauthors=Wissing J, Jänsch L, Nimtz M, etal |title=Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. |journal=Mol. Cell. Proteomics |volume=6 |issue= 3 |pages= 537–47 |year= 2007 |pmid= 17192257 |doi= 10.1074/mcp.T600062-MCP200 }}
*{{cite journal | author=Wissing J, Jänsch L, Nimtz M, ''et al.'' |title=Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. |journal=Mol. Cell Proteomics |volume=6 |issue= 3 |pages= 537-47 |year= 2007 |pmid= 17192257 |doi= 10.1074/mcp.T600062-MCP200 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{Serine/threonine-specific protein kinases}}
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{{Enzymes}}
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[[Category:EC 2.7.11]]
 
 
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Revision as of 20:33, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Serine/threonine-protein kinase PCTAIRE-3 is an enzyme that in humans is encoded by the PCTK3 gene.[1][2]


References

  1. ↑ Okuda T, Cleveland JL, Downing JR (Dec 1992). "PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family". Oncogene. 7 (11): 2249–58. PMID 1437147.
  2. ↑ "Entrez Gene: PCTK3 PCTAIRE protein kinase 3".

Further reading


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