Bone morphogenetic protein 15

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Bone Morphogentic Protein 15
Other names: Growth differentiation factor 9B (GDF9b)
Genetic data
Locus: Chr. X p11.2
Gene code: HUGO code: BMP15
Protein Structure/Function
Functions: cell signaling
Domains: TGFβ
Other
Taxa expressing: many metazoan phyla
Cell types: mesenchymal
Medical/Biotechnological data
Diseases: ovarian disgenesis 2
Database Links
Entrez: 9210
OMIM: 300247
RefSeq: NM_005448
UniProt: O95972


Bone morphogenetic protein 15 is a member of the TGF-β superfamily of proteins. It is a paracrine signaling molecule involved in oocyte and follicular development. Using Northern blot analysis, BMP15 has been shown to be exclusively expressed in the ovaries. It can be a homodimer or heterodimer.



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