GDF1
| growth differentiation factor 1
| |
| Identifiers | |
| Symbol | GDF1 |
| Entrez | 2657 |
| HUGO | 4214 |
| OMIM | 602880 |
| RefSeq | NM_001492 |
| UniProt | P27539 |
| Other data | |
| Locus | Chr. 19 p12 |
Growth differentiation factor-1 (GDF1) is a protein belonging to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.[1] It is found in the brain, spinal cord and peripheral nerves of embryos[2][3]
References
- ↑ Rankin C, Bunton T, Lawler A, Lee S (2000). "Regulation of left-right patterning in mice by growth/differentiation factor-1". Nat Genet 24 (3): 262-5. PMID 10700179.
- ↑ Lee S (1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure". Proc Natl Acad Sci U S A 88 (10): 4250-4. PMID 2034669.
- ↑ Rankin C, Bunton T, Lawler A, Lee S (2000). "Regulation of left-right patterning in mice by growth/differentiation factor-1". Nat Genet 24 (3): 262-5. PMID 10700179.
 | This protein-related article is a stub. You can help WikiDoc by expanding it. |
Cell signaling: TGF beta signaling pathway | |
|---|---|
| TGF beta superfamily of ligands | TGF beta family (TGF-β1, TGF-β2, TGF-β3) Bone morphogenetic proteins (BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMP8a, BMP8b, BMP10 , BMP15) Growth differentiation factors (GDF1, GDF2, GDF3, GDF5, GDF6, GDF7, Myostatin/GDF8, GDF9, GDF10, GDF11, GDF15) Other (Activin A and B/Inhibin A and B, Anti-müllerian hormone, Nodal) |
| TGF beta receptors | TGFBR1: Activin type 1 receptors (ACVR1, ACVR1B, ACVR1C) - ACVRL1 - BMPR1 (BMPR1A - BMPR1B) TGFBR2: Activin type 2 receptors (ACVR2A, ACVR2B) - AMHR2 - BMPR2 TGFBR3: betaglycan |
| Transducers/SMAD | R-SMAD (SMAD1, SMAD2, SMAD3, SMAD5, SMAD9) - I-SMAD (SMAD6, SMAD7) - SMAD4 |
| Ligand Inhibitors | Cerberus - Chordin - DAN - Decorin - Follistatin - Gremlin - Lefty - LTBP1 - Noggin - THBS1 |
| Coreceptors | BAMBI - Cripto |
| Other | SARA |
Navigation WikiDoc | WikiPatient | Popular pages | Recently Edited Pages | Recently Added
Pictures
There is no pharmaceutical or device industry support for this site and we need your viewer supported Donations | Editorial Board | Governance | Licensing | Disclaimers | Avoid Plagiarism | Policies
Table of Contents In Alphabetical Order | By Individual Diseases | Signs and Symptoms | Physical Examination | Lab Tests | Drugs
Editor Tools Become an Editor | Editors Help Menu | Create a Page | Edit a Page | Upload a Picture or File | Printable version | Permanent link | Maintain Pages | What Pages Link HereThere is no pharmaceutical or device industry support for this site and we need your viewer supported Donations | Editorial Board | Governance | Licensing | Disclaimers | Avoid Plagiarism | Policies
