Angiopathy

Jump to: navigation, search
Diabetic angiopathy
ICD-10 E10.5, E11.5, E12.5, E13.5, E14.5
ICD-9 250.7

WikiDoc Resources for Angiopathy

Articles

Most recent articles on Angiopathy

Most cited articles on Angiopathy

Review articles on Angiopathy

Articles on Angiopathy in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Angiopathy

Images of Angiopathy

Photos of Angiopathy

Podcasts & MP3s on Angiopathy

Videos on Angiopathy

Evidence Based Medicine

Cochrane Collaboration on Angiopathy

Bandolier on Angiopathy

TRIP on Angiopathy

Clinical Trials

Ongoing Trials on Angiopathy at Clinical Trials.gov

Trial results on Angiopathy

Clinical Trials on Angiopathy at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Angiopathy

NICE Guidance on Angiopathy

NHS PRODIGY Guidance

FDA on Angiopathy

CDC on Angiopathy

Books

Books on Angiopathy

News

Angiopathy in the news

Be alerted to news on Angiopathy

News trends on Angiopathy

Commentary

Blogs on Angiopathy

Definitions

Definitions of Angiopathy

Patient Resources / Community

Patient resources on Angiopathy

Discussion groups on Angiopathy

Patient Handouts on Angiopathy

Directions to Hospitals Treating Angiopathy

Risk calculators and risk factors for Angiopathy

Healthcare Provider Resources

Symptoms of Angiopathy

Causes & Risk Factors for Angiopathy

Diagnostic studies for Angiopathy

Treatment of Angiopathy

Continuing Medical Education (CME)

CME Programs on Angiopathy

International

Angiopathy en Espanol

Angiopathy en Francais

Business

Angiopathy in the Marketplace

Patents on Angiopathy

Experimental / Informatics

List of terms related to Angiopathy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries). The best known and most prevalent angiopathy is the diabetic angiopathy, a complication that may occur in chronic diabetes.

There are two types of angiopathy: macroangiopathy and microangiopathy. In macroangiopathy, fat and blood clots build up in the large blood vessels, stick to the vessel walls, and block the flow of blood. In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they bleed, leak protein, and slow the flow of blood through the body. The decrease of blood flow through stenosis or clot formation impair the flow of oxygen to cells and biological tissues (called ischemia) and lead to their death (necrosis and gangrene, which in turn may require amputation). Thus, tissues which are very sensitive to oxygen levels, such as the retina, develop microangiopathy and may cause blindness (so-called proliferative diabetic retinopathy). Damage to nerve cells may cause peripheral neuropathy, and to kidney cells, diabetic nephropathy (Kimmelstiel-Wilson syndrome).

Macroangiopathy, on the other hand, may cause other complications, such as ischemic heart disease, stroke and peripheral vascular disease which contributes to the diabetic foot ulcers and the risk of amputation.

Diabetes mellitus is the most common cause of adult kidney failure worldwide. It also the most common cause of amputation in the US, usually toes and feet, often as a result of gangrene, and almost always as a result of peripheral vascular disease. Retinal damage (from microangiopathy) makes it the most common cause of blindness among non-elderly adults in the US.

"Diabetic dermopathy" is a manifestation of diabetic angiopathy. It is often found on the shin.

There is also Neuropathy; also associated with diabetes mellitus; type 1 and 2.

See also

External links


Cardiology


Linked-in.jpg