Pheochromocytoma risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]

Overview

Pheochromocytoma is more common in third decade of life, people with family history of multiple endocrine neoplasias, Von Hippel-Lindau disease, neurofibromatosis type 1, hereditary paraganglioma syndromes.

Risk Factors

The most potent risk factors of pheochromocytoma are:

Age

  • Occurs in third decade of life; the average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases.[1]
  • Hereditary tumors present at a younger age than sporadic.

Family history

Ten percent of pheochromocytomas are linked to hereditary causes:

MEN1 MEN2

References

  1. National Cancer Institute. Physician Data Query Database 2015. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc

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