Pheochromocytoma (patient information)

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Pheochromocytoma

Overview

What are the symptoms?

What are the causes?

When to seek urgent medical care?

Diagnosis

Treatment options

Prevention

Where to find medical care for Pheochromocytoma?

What to expect (Outlook/Prognosis)?

Possible complications

Prevention

Pheochromocytoma On the Web

Ongoing Trials at Clinical Trials.gov

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FDA on Pheochromocytoma

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Directions to Hospitals Treating Pheochromocytoma

Risk calculators and risk factors for Pheochromocytoma

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Pheochromocytoma is a rare tumor of adrenal gland tissue. It results in the release of too much epinephrine and norepinephrine, hormones that control heart rate, metabolism, and blood pressure .

What are the symptoms of Pheochromocytoma?

Other symptoms that can occur with this disease:

Symptom attacks may occur at unpredictable intervals and usually last 15 to 20 minutes. The attacks may increase in frequency, length, and severity as the tumor grows.

What causes Pheochromocytoma?

Pheochromocytoma may occur as a single tumor or as more than one growth. It usually develops in the center (medulla) of one or both adrenal glands. Rarely, this kind of tumor occurs outside the adrenal gland, usually somewhere else in the abdomen.

Very few pheochromocytomas are cancerous.

The tumors may occur at any age, but they are most common from early to mid-adulthood.

When to seek urgent medical care?

Call your health care provider if:

  • You have symptoms of pheochromocytoma
  • You had a pheochromocytoma in the past and your symptoms return

Diagnosis

The doctor will perform a physical exam. You may have high blood pressure, rapid heart rate, and fever during an attack of symptoms. Your vital signs can be normal at other times.

Tests include:

Treatment options

Treatment involves removing the tumor with surgery. It is important to stabilize blood pressure and pulse with medication before surgery. You may need to stay in the hospital with close monitoring of your vital signs.

After surgery, it is necessary to continually monitor all vital signs in an intensive care unit. When the tumor cannot be surgically removed, medication is needed to manage it. This usually requires a combination of medications to control the effects of the excessive hormones. Radiation therapy and chemotherapy have not been effective in curing this kind of tumor.

Medications to avoid

Patients diagnosed with pheochromocytoma should avoid using the following medications:

  • Atomoxetine
  • Metoclopramide
    If you have been diagnosed with pheochromocytoma, consult your physician before starting or stopping any of these medications.


Where to find medical care for Pheochromocytoma?

Directions to Hospitals Treating Pheochromocytoma

What to expect (Outlook/Prognosis)?

Most patients who have noncancerous tumors that are removed with surgery are still alive after 5 years. The tumors come back in less than 10% of these patients. Levels of the hormones norepinephrine and epinephrine return to normal after surgery.

Possible complications

High blood pressure may not be cured in 25% of patients after surgery. However, standard treatments can usually control high blood pressure. In about 10% of people, the tumor may return.

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000340.htm


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