Chronotropic
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Most recent articles on Chronotropic Most cited articles on Chronotropic | |
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Overview
Chronotropic effects (from chrono-, meaning time) are those that change the heart rate.
Chronotropic drugs may change the heart rate by affecting the nerves controlling the heart, or by changing the rhythm produced by the sinoatrial node. Positive chronotropes increase heart rate; however, negative chronotropes decrease heart rate.
A dromotrope affects Atrioventricular node (AV node) conduction. A positive dromotrope increases AV nodal conduction, and a negative dromotrope decreases AV nodal conduction. A lusitrope is an agent that affects diastolic relaxation.
Many positive inotropes affect preload and afterload.
Negative Chronotropes
Chronotropic variables in systolic myocardial performance can be split left and right. Left sided systolic chronotropy can be appreciated as Aortic Valve open to close time. Right sided variables are represented by Pulmonary valve open to close time. Inverted as diastolic chronotropy, the variables are aortic valve close to open and pulmonic close to open time. Pharmaceutical manipulation of chronotropic properties was perhaps first appreciated by the introduction of digitalis.
Positive Chronotropes
WikiDoc Research Resources for Chronotropic | |
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| Articles on Chronotropic | Most recent articles on Chronotropic • Most cited articles on Chronotropic • Review articles on Chronotropic • Articles on Chronotropic in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Chronotropic | Powerpoint slides on Chronotropic • Images of Chronotropic • Photos of Chronotropic • Podcasts & MP3s on Chronotropic • Videos on Chronotropic |
| Evidence Based Medicine Regarding Chronotropic | Cochrane Collaboration on Chronotropic • Bandolier on Chronotropic • TRIP on Chronotropic |
| Cost Effectiveness of Chronotropic | Cost Effectiveness of Chronotropic |
| Clinical Trials Involving Chronotropic | Ongoing Trials on Chronotropic at Clinical Trials.gov • Trial results on Chronotropic • Clinical Trials on Chronotropic at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Chronotropic | US National Guidelines Clearinghouse on Chronotropic • NICE Guidance on Chronotropic • NHS PRODIGY Guidance • FDA on Chronotropic • CDC on Chronotropic |
| Textbook Information on Chronotropic | Books and Textbook Information on Chronotropic |
| Pharmacology Resources on Chronotropic | Dosing of Chronotropic • Drug interactions with Chronotropic • Side effects of Chronotropic • Allergic reactions to Chronotropic • Overdose information on Chronotropic • Carcinogenicity information on Chronotropic • Chronotropic in pregnancy • Pharmacokinetics of Chronotropic • |
| Genetics, Pharmacogenomics, and Proteinomics of Chronotropic | Genetics of Chronotropic • Pharmacogenomics of Chronotropic • Proteomics of Chronotropic |
| Newstories on Chronotropic | Chronotropic in the news • Be alerted to news on Chronotropic • News trends on Chronotropic |
| Commentary on Chronotropic | Blogs on Chronotropic |
| Patient Resources on Chronotropic | Patient resources on Chronotropic • Discussion groups on Chronotropic • Patient Handouts on Chronotropic • Directions to Hospitals Treating Chronotropic • Risk calculators and risk factors for Chronotropic |
| Healthcare Provider Resources on Chronotropic | Symptoms of Chronotropic • Causes & Risk Factors for Chronotropic • Diagnostic studies for Chronotropic • Treatment of Chronotropic |
| Continuing Medical Education (CME) Programs on Chronotropic | CME Programs on Chronotropic |
| International Resources on Chronotropic | Chronotropic en Espanol • Chronotropic en Francais |
| Business Resources on Chronotropic | Chronotropic in the Marketplace • Patents on Chronotropic |
| Informatics Resources on Chronotropic | List of terms related to Chronotropic |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
