TRPV2

Transient receptor potential cation channel, subfamily V, member 2
File:PBB Protein TRPV2 image.jpg PDB rendering based on 2f37.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2f37​
Identifiers
Symbols	TRPV2 ; MGC12549; VRL; VRL-1; VRL1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 7993
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TRPV2 219282 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Transient receptor potential cation channel, subfamily V, member 2, also known as TRPV2, is a human gene.

This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.

See also

• TRPV

Further reading

• Tominaga M, Julius D (2000). "Capsaicin receptor in the pain pathway". Jpn. J. Pharmacol. 83 (1): 20–4. PMID 10887936.
• Benham CD, Gunthorpe MJ, Davis JB (2004). "TRPV channels as temperature sensors". Cell Calcium. 33 (5–6): 479–87. PMID 12765693.CS1 maint: Multiple names: authors list (link)
• Heiner I, Eisfeld J, Lückhoff A (2004). "Role and regulation of TRP channels in neutrophil granulocytes". Cell Calcium. 33 (5–6): 533–40. PMID 12765698.CS1 maint: Multiple names: authors list (link)
• Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.CS1 maint: Multiple names: authors list (link)

External links

• TRPV2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.