CLIC1

Jump to: navigation, search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene.[1][2]

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.[2]

Interactions

CLIC1 has been shown to interact with TRAPPC2.[3]

See also

References

  1. Valenzuela SM, Martin DK, Por SB, Robbins JM, Warton K, Bootcov MR, Schofield PR, Campbell TJ, Breit SN (Jun 1997). "Molecular cloning and expression of a chloride ion channel of cell nuclei". J Biol Chem. 272 (19): 12575–82. doi:10.1074/jbc.272.19.12575. PMID 9139710.
  2. 2.0 2.1 "Entrez Gene: CLIC1 chloride intracellular channel 1".
  3. Fan, Libin; Yu Wei; Zhu Xueliang (Apr 2003). "Interaction of Sedlin with chloride intracellular channel proteins". FEBS Lett. Netherlands. 540 (1–3): 77–80. doi:10.1016/S0014-5793(03)00228-X. ISSN 0014-5793. PMID 12681486.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



Linked-in.jpg