Sandbox chemo1
Chemotherapeutic Agents by Category
Alkylating agents
Nitrogen mustards
- Chlorambucil (Leukeran)
- Cyclophosphamide (Cytoxan)
- Ifosfamide (Iflex)
- Melphalan (Alkeran)
- Mechlorethamine (Mustargen)
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes
Antimetabolites
Folic acid analogs
Pyrimidine analogs
- Azacytidine (Vidaza)
- Capecitabine (Xeloda)
- Cytarabine (Cytosar)
- Floxuridine (FUDR)
- Fluorouracil (Adrucil, Efudex)
- Gemcitabine (Gemzar)
Purine analogs
- Cladribine (Leustatin)
- Clofarabine (Clolar)
- Fludarabine (Fludara)
- Mercaptopurine (Purinethol)
- Nelarabine (Arranon)
- Pentostatin (Nipent)
- Thioguanine (Tabloid)
Ribonucleotide reductase inhibitors
Natural products
Vinca alkaloids
- Vinblastine (Velban, Velsar)
- Vincristine (Oncovin, Vincasar)
- Vincristine liposome (Marqibo)
- Vinorelbine (Navelbine)
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
- Bleomycin (Blenoxane)
- Dactinomycin (Cosmegen)
- Daunorubicin (Daunoxome)
- Doxorubicin (Adriamycin, Rubex)
- Epirubicin (Ellence)
- Idarubicin (Idamycin)
- Mitomycin C (Mutamycin)
- Mitoxantrone (Novantrone)
- Valrubicin (Valstar)
Antineoplastic enzymes
Hormones and Antagonists
Adrenocortical suppressants
Antiandrogens
- Abiraterone (Zytiga)
- Bicalutamide (Casodex)
- Dutasteride (Avodart)
- Enzalutamide (Xtandi)
- Finasteride (Proscar)
- Flutamide (Eulexin)
- Ketoconazole (Nizoral)
- Leuprolide (Lupron)
- Nilutamide (Nilandron)
- Triptorelin (Trelstar)
Steroid synthesis inhibitors
- Abiraterone (Zytiga)
- Aminoglutethimide (Cytadren)
- Anastrozole (Arimidex)
- Exemestane (Aromasin)
- Letrozole (Femara)
- Mitotane (Lysodren)
Androgen receptor inhibitors
5α-reductase inhibitors
GnRH agonists
GnRH antagonists
Aromatase inhibitors
Selective estrogen receptor modulators
Biologics
Antibody medications
- Cetuximab (Erbitux)
- Denosumab (Xgeva)
- Ibritumomab tiuxetan (Zevalin)
- Ipilimumab (Yervoy)
- Nivolumab (Opdivo)
- Obinutuzumab (Gazyva)
- Ofatumumab (Arzerra)
- Pembrolizumab (KEYTRUDA)
Antibody-drug conjugates
Anti-HER2 medications
Enzymes
IL-6 inhibitors
IL-2 inhibitors
Immunotherapy
Immunomodulatory drugs (IMiDs)
Hematopoietic Growth Factors
Erythrocyte growth factors
Granulocyte growth factors
Megakaryocyte growth factors
Supportive Medications
Chemotherapy protective agents
- Amifostine (Ethyol)
- Cyanocobalamin
- Dexrazoxane (Zinecard)
- Folinic acid (Leucovorin)
- Glucarpidase (Voraxaze)
- Levoleucovorin (Fusilev)
- Mesna (Mesnex)
Antiemetic agents
RANK ligand inhibitors
Miscellaneous
Bisphosphonate
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
- Afatinib (Gliotrif)
- Cabozantinib (Cometriq)
- Crizotinib (Xalkori)
- Dasatinib (Sprycel)
- Erlotinib (Tarceva)
- Gefitinib
- Ibrutinib (Imbruvica)
- Idelalisib (Zydelig)
- Lapatinib (Tykerb)
- Nilotinib (Tasigna)
- Palbociclib (Ibrance)
- Sorafenib
- Sunitinib
Proteasome inhibitors
Radioactive agents
Somatostatin analogues
VEGF receptor-2 antagonists
Antimitotic agent