Multiple endocrine neoplasia type 2 history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
The hallmark of multiple endocrine neoplasia type 2 is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. | |||
The | ==History and Symptoms== | ||
* Tall, thin, "[[Marfan syndrome|marfanoid]]" body build, in which long [[bone]]s are disproportionately elongated. | |||
* Masses beneath [[mucosal]] surfaces in the [[mouth]], [[lip]]s, and [[eye]]s. Numerous yellowish-white, sessile, painless [[Nodule (medicine)|nodules]] on the [[lip]]s or [[tongue]], with deeper lesions having normal coloration. There may be enough [[neuroma]]s in the [[body]] of the [[lip]]s to produce enlargement and a "blubbery [[lip]]" appearance. Similar [[Nodule (medicine)|nodules]] may be seen on the [[sclera]] and [[eyelid]]s | |||
* Low [[muscle]] [[mass]], sometimes with [[myopathy]] | |||
* [[Weight loss]] | |||
* [[Delayed puberty]] | |||
* [[Sweating]] | |||
*[[Hand]] [[tremor]] | |||
* [[Sleeping difficulty]] | |||
* [[Lethargy]] | |||
==Symptoms== | |||
===Gastrointestinal Symptoms=== | |||
* [[Dysphagia|Trouble swallowing]] | |||
* Tall, thin, "[[Marfan syndrome|marfanoid]]" body build, in which long | * [[Diarrhea]] | ||
* Masses beneath mucosal surfaces in the mouth, | * [[Abdominal pain]] | ||
* Low muscle mass, sometimes with myopathy | * [[Constipation]] | ||
* | * [[Nausea]] | ||
* | * [[Anorexia|Decreased appetite]] | ||
* [[ | |||
* [[ | ===Respiratory Symptoms=== | ||
* Trouble swallowing | *[[Breathing]] problems | ||
* Breathing problems | |||
* Continuous [[cough]] | * Continuous [[cough]] | ||
* [[Cough]] with [[blood]] | |||
===Cardiovascular Symptoms=== | |||
* [[Chest pain]] | |||
* [[Palpitations]] | * [[Palpitations]] | ||
* [[Anxiety]] often resembling that of a [[panic attack]] | * [[Anxiety]] often resembling that of a [[panic attack]] | ||
* [[Diaphoresis]] | * [[Diaphoresis]] | ||
===Neurologic Symptoms=== | |||
* [[Headaches]] | * [[Headaches]] | ||
* [[ | *[[Irritability]] | ||
* [[ | * Nervousness | ||
* [[ | * [[Confusion]] | ||
===Ophthalmology Symptoms=== | |||
== | * [[Dry eye]]s or lack of [[tears]], which is an especially helpful [[Medical sign|sign]] in children. | ||
{{ | |||
==References== | |||
{{reflist|2}} | |||
[[Category:Endocrinology]] | |||
[[Category:Oncology]] | |||
[[CAtegory:Diseases]] | |||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Up-To-Date]] | |||
| |||
{{WS}} | |||
{{WH}} | |||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Surgery]] | |||
Latest revision as of 12:13, 24 June 2019
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Multiple endocrine neoplasia type 2 Microchapters |
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Differentiating Multiple endocrine neoplasia type 2 from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
The hallmark of multiple endocrine neoplasia type 2 is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
- Tall, thin, "marfanoid" body build, in which long bones are disproportionately elongated.
- Masses beneath mucosal surfaces in the mouth, lips, and eyes. Numerous yellowish-white, sessile, painless nodules on the lips or tongue, with deeper lesions having normal coloration. There may be enough neuromas in the body of the lips to produce enlargement and a "blubbery lip" appearance. Similar nodules may be seen on the sclera and eyelids
- Low muscle mass, sometimes with myopathy
- Weight loss
- Delayed puberty
- Sweating
- Hand tremor
- Sleeping difficulty
- Lethargy
Gastrointestinal Symptoms
Respiratory Symptoms
Cardiovascular Symptoms
- Chest pain
- Palpitations
- Anxiety often resembling that of a panic attack
- Diaphoresis
Neurologic Symptoms
- Headaches
- Irritability
- Nervousness
- Confusion