Multiple endocrine neoplasia type 2 diagnostic criteria

Jump to navigation Jump to search

Multiple endocrine neoplasia type 2 Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Multiple endocrine neoplasia type 2 from other Diseases

Epidemiology & Demographics

Risk Factors

Screening

Natural History, Complications & Prognosis

Diagnosis

Diagnostic Criteria

History & Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Multiple endocrine neoplasia type 2 diagnostic criteria On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Multiple endocrine neoplasia type 2 diagnostic criteria

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Multiple endocrine neoplasia type 2 diagnostic criteria

CDC on Multiple endocrine neoplasia type 2 diagnostic criteria

Multiple endocrine neoplasia type 2 diagnostic criteria in the news

Blogs on Multiple endocrine neoplasia type 2 diagnostic criteria

Directions to Hospitals Treating Multiple endocrine neoplasia type 2

Risk calculators and risk factors for Multiple endocrine neoplasia type 2 diagnostic criteria

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

According to the American Society of Clinical Oncology, diagnosis of multiple endocrine neoplasia type 2 requires existence of two or more specific endocrine tumors (medullary thyroid carcinoma, pheochromocytoma, or parathyroid hyperplasia). Multiple endocrine neoplasia type 2 is also diagnosed with four or more cases of medullary thyroid carcinoma without pheochromocytoma and parathyroid adenoma or if there is early onset of medullary thyroid carcinoma, mucosal neuromas of lips and tongue, disctinctive facial features with enlarged lips and marfanoid body habitus.

Diagnostic Critera

  • The current clinical criteria for detecting Multiple endocrine neoplasia type 2 is as follows:[1][2][3]
Clinical criteria for diagnosis of Multiple endocrine neoplasia type 2
Two or more specific endocrine tumors (medullary thyroid carcinoma, pheochromocytoma or parathyroid hyperplasia)
Familial medullary thyroid carcinoma is diagnosed in families with four or more cases of medullary thyroid carcinoma without pheochromocytoma and parathyroid adenoma
Multiple endocrine neoplasia type 2b is diagnosed if there is early onset of medullary thyroid carcinoma, mucosal neuromas of lips and tongue, disctinctive facial features with enlarged lips and marfanoid body habitus







References

  1. "Genetics-University of Washington, Seattle".
  2. Haruhiro Sato, Yasuhiro Suzuki, Maki Fukasawa, Masanori Yasuda & Robert Yoshiyuki Osamura (2006). "De novo multiple endocrine neoplasia type 2B with noncardiogenic pulmonary edema as the presenting symptom". Endocrine journal. 53 (4): 523–529. PMID 16829704. Unknown parameter |month= ignored (help)
  3. Romei, C.; Pardi, E.; Cetani, F.; Elisei, R. (2012). "Genetic and Clinical Features of Multiple Endocrine Neoplasia Types 1 and 2". Journal of Oncology. 2012: 1–15. doi:10.1155/2012/705036. ISSN 1687-8450.


Template:WikiDoc Sources