Multiple endocrine neoplasia type 2 history and symptoms: Difference between revisions

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VisualWikitext

Latest revision as of 12:13, 24 June 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The hallmark of multiple endocrine neoplasia type 2 is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

Tall, thin, "marfanoid" body build, in which long bones are disproportionately elongated.
Masses beneath mucosal surfaces in the mouth, lips, and eyes. Numerous yellowish-white, sessile, painless nodules on the lips or tongue, with deeper lesions having normal coloration. There may be enough neuromas in the body of the lips to produce enlargement and a "blubbery lip" appearance. Similar nodules may be seen on the sclera and eyelids
Low muscle mass, sometimes with myopathy
Weight loss
Delayed puberty
Sweating
Hand tremor
Sleeping difficulty
Lethargy

Gastrointestinal Symptoms

Respiratory Symptoms

Breathing problems
Continuous cough
Cough with blood

Cardiovascular Symptoms

Chest pain
Palpitations
Anxiety often resembling that of a panic attack
Diaphoresis

Neurologic Symptoms

Ophthalmology Symptoms

Dry eyes or lack of tears, which is an especially helpful sign in children.

References

Template:WS Template:WH

@@ Line 3: / Line 3: @@
 {{CMG}}; {{AE}} {{Ammu}}
 ==Overview==
-==History==
+The hallmark of  multiple endocrine neoplasia type 2 is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
-==Symptoms==
-===Multiple endocrine neoplasia type 2b===
+==History and Symptoms==
-The most common clinical features of MEN2B are:
+* Tall, thin, "[[Marfan syndrome|marfanoid]]" body build, in which long [[bone]]s are disproportionately elongated.
-* Tall, thin, "[[Marfan syndrome|marfanoid]]" body build, in which long bones are disproportionately elongated
+* Masses beneath [[mucosal]] surfaces in the [[mouth]], [[lip]]s, and [[eye]]s. Numerous yellowish-white, sessile, painless [[Nodule (medicine)|nodules]] on the [[lip]]s or [[tongue]], with deeper lesions having normal coloration. There may be enough [[neuroma]]s in the [[body]] of the [[lip]]s to produce enlargement and a "blubbery [[lip]]" appearance. Similar [[Nodule (medicine)|nodules]] may be seen on the [[sclera]] and [[eyelid]]s
-* Masses beneath mucosal surfaces in the mouth, lips, and eyes. Numerous yellowish-white, sessile, painless nodules on the lips or tongue, with deeper lesions having normal coloration. There may be enough [[neuroma]]s in the body of the lips to produce enlargement and a "blubbery lip" appearance. Similar nodules may be seen on the [[sclera]] and eyelids.
+* Low [[muscle]] [[mass]], sometimes with [[myopathy]]
-* Low muscle mass, sometimes with myopathy
+* [[Weight loss]]
-* Gastrointestinal complaints, especially constipation
+* [[Delayed puberty]]
-* A nodule, [[lump]], or swelling in the neck
+* [[Sweating]]
-* [[Pain]] in the front of the neck
+*[[Hand]] [[tremor]]
-* [[Hoarseness]] or other voice changes
+* [[Sleeping difficulty]]
-* Trouble swallowing
+* [[Lethargy]]
-* Breathing problems
+===Gastrointestinal Symptoms===
+* [[Dysphagia|Trouble swallowing]]
+* [[Diarrhea]]
+* [[Abdominal pain]]
+* [[Constipation]]
+* [[Nausea]]
+* [[Anorexia|Decreased appetite]]
+===Respiratory Symptoms===
+*[[Breathing]] problems
 * Continuous [[cough]]
-* Symptoms derived from [[pheochromocytoma]]
+* [[Cough]] with [[blood]]
-* [[Craniosynostosis]]
-* Dry eyes or lack of tears, which is an especially helpful sign in children
+===Cardiovascular Symptoms===
-* Delayed puberty
+* [[Chest pain]]
+* [[Palpitations]]
+* [[Anxiety]] often resembling that of a [[panic attack]]
+* [[Diaphoresis]]
+===Neurologic Symptoms===
+* [[Headaches]]
+*[[Irritability]]
+* Nervousness
+* [[Confusion]]
+===Ophthalmology Symptoms===
+* [[Dry eye]]s or lack of [[tears]], which is an especially helpful [[Medical sign|sign]] in children.
+==References==
+{{reflist|2}}
+[[Category:Endocrinology]]
+[[Category:Oncology]]
+[[CAtegory:Diseases]]
+[[Category:Medicine]]
+[[Category:Endocrinology]]
+[[Category:Up-To-Date]]
+{{WS}}
+{{WH}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Endocrinology]]
+[[Category:Surgery]]