Eosinophilia: Difference between revisions

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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| [[Erythema multiforme]], [[Atopic dermatitis]], [[Dermatitis herpetiformis]], [[fasciitis|Eosinophilic fasciitis]], [[folliculitis|Eosinophilic pustular folliculitis]], [[Pemphigus vulgaris]], [[Psoriasis]], [[Systemic lupus erythematosus]], [[Scabies|Sarcoptes scabiei]],  
|bgcolor="Beige"| [[Erythema multiforme]], [[Atopic dermatitis]], [[Dermatitis herpetiformis]], [[fasciitis|Eosinophilic fasciitis]], [[folliculitis|Eosinophilic pustular folliculitis]], [[Pemphigus vulgaris]], [[Psoriasis]], [[Systemic lupus erythematosus]], [[Scabies|Sarcoptes scabiei]], [[Eczema ]], [[Exfoliative dermatitis  ]], [[Urticaria ]], [[Eosinophilic panniculitis    ]], [[Shulman’s syndrome ]], [[Stevens -  Johnson syndrome ]], [[Duhring disease ]], [[Histiositosis with Cutaneous involvement ]]
[[Eczema ]]
 
[[Exfoliative dermatitis  ]]
 
[[Urticaria ]]
 
[[Eosinophilic panniculitis    ]]
 
[[Shulman’s syndrome ]]
 
[[Stevens -  Johnson syndrome ]]
 
[[Duhring disease ]]
[[Histiositosis with Cutaneous involvement ]]


|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Sulphonamides]], [[Allopurinol]], [[Amitriptyline]], [[Capreomycin]], [[Caspofungin]], [[Chlorpropamide]], [[Clomipramine]], [[Daptomycin]], [[Desipramine]], [[Dothiepin]], [[Doxycycline]], [[Enfuvirtide]], [[Etravirine]], [[Gold salts]], [[Granulocyte-macrophage colony stimulating factor]], [[Hydralazine]], [[Imipramine]], [[Interleukin 2]], [[Micafungin]], [[Minocycline]], [[Nalidixic acid]], [[Nitrofurantoin]], [[Nortriptyline]], [[Olanzapine]], [[Oxytetracycline]], [[Pentostatin]], [[Procarbazine]], [[Smoking|Tobacco smoking]], [[Tryptophan]], [[Vancomycin]],  
|bgcolor="Beige"| [[Sulphonamides]], [[Allopurinol]], [[Amitriptyline]], [[Capreomycin]], [[Caspofungin]], [[Chlorpropamide]], [[Clomipramine]], [[Daptomycin]], [[Desipramine]], [[Dothiepin]], [[Doxycycline]], [[Enfuvirtide]], [[Etravirine]], [[Gold salts]], [[Granulocyte-macrophage colony stimulating factor]], [[Hydralazine]], [[Imipramine]], [[Interleukin 2]], [[Micafungin]], [[Minocycline]], [[Nalidixic acid]], [[Nitrofurantoin]], [[Nortriptyline]], [[Olanzapine]], [[Oxytetracycline]], [[Pentostatin]], [[Procarbazine]], [[Smoking|Tobacco smoking]], [[Tryptophan]], [[Vancomycin]], [[Aldesleukin ]], [[Amikacin Sulfate  ]], [[Capastat Sulfate ]], [[Capreomycin Sulfate  ]], [[Cefotaxime Sodium  ]], [[Cefoxitin Sodium ]], [[Ceftazidime ]], [[Cefuroxime ]], [[LyphocinMaolate]]
[[Aldesleukin ]]
 
[[Amikacin Sulfate  ]]
 
[[Capastat Sulfate ]]
 
[[Capreomycin Sulfate  ]]
 
[[Cefotaxime Sodium  ]]
 
[[Cefoxitin Sodium ]]
 
[[Ceftazidime ]]
 
[[Cefuroxime ]]
 
[[LyphocinMaolate]]


|-
|-
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| [[Adrenal cortex insufficiency]],  
|bgcolor="Beige"| [[Adrenal cortex insufficiency]], [[Addisons disease ]], [[Adrenocortical insufficiency]]
[[Addisons disease ]]
 
[[Adrenocortical insufficiency]]


|-  
|-  
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"|  
|bgcolor="Beige"| [[Inflammatory Bowel Disease ]], [[Cirrhosis of liver ]], [[Chronic active hepatitis ]], [[Eosinophilic Gastroenteritis ]], [[Peritoneal dialysis ]]
[[Inflammatory Bowel Disease ]]
 
[[Cirrhosis of liver ]]
 
[[Chronic active hepatitis ]]
 
[[Eosinophilic Gastroenteritis ]]
 
[[Peritoneal dialysis ]]


|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 1]], [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 2]], [[Familial eosinophilia]], [[Kostmann disease]], [[Omenn syndrome]], [[Wiskott-Aldrich syndrome]],  
|bgcolor="Beige"| [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 1]], [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 2]], [[Familial eosinophilia]], [[Kostmann disease]], [[Omenn syndrome]], [[Wiskott-Aldrich syndrome]], [[TAR syndrome]], [[kostmann syndrome]], [[chromosome 21 partial deletion ]]
[[TAR syndrome]]
 
[[kostmann syndrome]]
 
[[chromosome 21 partial deletion   ]]


|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]],  
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]], [[Thrombocytopenia  with absent radii ]], [[Familial reticuloendotheliosis with  eosinophilia]]
[[Thrombocytopenia  with absent radii ]]
 
[[Familial reticuloendotheliosis with  eosinophilia]]


|-
|-
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''  
| '''Infectious Disease'''  
|bgcolor="Beige"| [[Acanthocheilonemiasis]], [[Alveolar hydatid disease]], [[Ancylostoma caninum]], [[Ancylostoma duodenale]], [[Angiostrongyliasis]], [[Anisakiasis]], [[Ascariasis]], [[Capillaria]], [[Clonorchiasis]], [[Coccidioidomycosis]], [[Dicrocoelium dendriticum fluke]], [[Dracunculiasis]], [[Echinococcus granulosus]], [[Fasciola hepatica]], [[Gnathostomiasis]], [[Heterophyiasis]], [[Lepromatous leprosy]], [[Loa loa filariasis]], [[Lymphatic filariasis]], [[Mansonelliasis]], [[Metagonimiasis]], [[Mycobacterium tuberculosis]], [[Onchocerciasis]], [[Opisthorchiasis]], [[Paragonimiasis]], [[Schistosoma haematobium]], [[Schistosoma mansoni]], [[Strongyloidiasis]], [[Toxocariasis]], [[Trichinella spiralis]],  
|bgcolor="Beige"| [[Acanthocheilonemiasis]], [[Alveolar hydatid disease]], [[Ancylostoma caninum]], [[Ancylostoma duodenale]], [[Angiostrongyliasis]], [[Anisakiasis]], [[Ascariasis]], [[Capillaria]], [[Clonorchiasis]], [[Coccidioidomycosis]], [[Dicrocoelium dendriticum fluke]], [[Dracunculiasis]], [[Echinococcus granulosus]], [[Fasciola hepatica]], [[Gnathostomiasis]], [[Heterophyiasis]], [[Lepromatous leprosy]], [[Loa loa filariasis]], [[Lymphatic filariasis]], [[Mansonelliasis]], [[Metagonimiasis]], [[Mycobacterium tuberculosis]], [[Onchocerciasis]], [[Opisthorchiasis]], [[Paragonimiasis]], [[Schistosoma haematobium]], [[Schistosoma mansoni]], [[Strongyloidiasis]], [[Toxocariasis]], [[Trichinella spiralis]], [[Pneumocystis  jirovecii infection ]], [[Visceral larva migrans ]], [[Brucellosis ]], [[Cat-scratch fever ]], [[Chlamydial pneumonia of infancy ]], [[Infectious lymphocytosis ]], [[Infectious mononucleosis ]], [[Scarlet fever]], [[Amebiasis ]], [[Malaria ]]
[[Pneumocystis  jirovecii infection ]]
 
[[Visceral larva migrans ]]
 
[[Brucellosis ]]
 
[[Cat-scratch fever ]]
 
[[Chlamydial pneumonia of infancy ]]
 
[[Infectious lymphocytosis ]]
 
[[Infectious mononucleosis ]]
 
[[Scarlet fever]]
 
[[Amebiasis ]]
 
[[Malaria ]]


|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
| '''Musculoskeletal / Ortho'''
|bgcolor="Beige"| [[Polyarteritis nodosa]], [[Polymyositis]], [[Rheumatoid disease]],  
|bgcolor="Beige"| [[Polyarteritis nodosa]], [[Polymyositis]], [[Rheumatoid disease]], [[Dressler's  syndrome ]], [[Eosinophilic fasciitis ]], [[Idiopathic eosinophilic synovitis ]], [[Progressive systemic sclerosis  (scleroderma) ]], [[SLE ]], [[Sjögren's syndrome ]], [[Sarcoidosis  ]], [[Eosinophilia – Myalgia syndrome ]], [[Dermatomyositis ]]
[[Dressler's  syndrome ]]
 
[[Eosinophilic fasciitis ]]
[[Idiopathic eosinophilic synovitis ]]
[[Progressive systemic sclerosis  (scleroderma) ]]
[[SLE ]]
 
[[Sjögren's syndrome ]]
 
[[Sarcoidosis  ]]
 
[[Eosinophilia – Myalgia syndrome ]]
 
[[Dermatomyositis ]]


|-
|-
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]],  
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]], [[Immunoblastic  lymphadenopathy ]], [[Sarcomas and carcinomas of Ovary]], [[Carcinoma of Pancreas ]], [[Carcinoma of Lung ]], [[Carcinoma of colon]], [[Carcinoma of cervix ]], [[Acute eosinophilic leukemia  ]], [[Chronic eosinophilic leukemia ]], [[Brain Tumors  ]]
[[Immunoblastic  lymphadenopathy ]]
 
[[Sarcomas and carcinomas of Ovary]]
 
[[Carcinoma of Pancreas ]]
 
[[Carcinoma of Lung ]]
 
[[Carcinoma of colon]]
 
[[Carcinoma of cervix ]]
 
[[Acute eosinophilic leukemia  ]]
[[Chronic eosinophilic leukemia ]]
 
[[Brain Tumors  ]]


|-
|-
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| [[Simple pulmonary eosinophilia]], [[Visceral larva migrans]], [[Allergic bronchopulmonary aspergillosis]], [[Extrinsic allergic alveolitis]], [[Tropical pulmonary eosinophilia]], [[Churg-Strauss syndrome]], [[Bronchial asthma]],  
|bgcolor="Beige"| [[Simple pulmonary eosinophilia]], [[Visceral larva migrans]], [[Allergic bronchopulmonary aspergillosis]], [[Extrinsic allergic alveolitis]], [[Tropical pulmonary eosinophilia]], [[Churg-Strauss syndrome]], [[Bronchial asthma]], [[Allergic  Rhinitis]], [[Chronic eosinophilic pneumonia ]], [[Occupational lung diseases ]], [[Idiopathic eosinophilic chronic  pneumopathy ]], [[Magrassi- Leonardi syndrome ]]
[[Allergic  Rhinitis]]
 
[[Chronic eosinophilic pneumonia ]]
 
[[Occupational lung diseases ]]
 
[[Idiopathic eosinophilic chronic  pneumopathy ]]
 
[[Magrassi- Leonardi syndrome ]]


|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
| '''Renal / Electrolyte'''
|bgcolor="Beige"| [[Interstitial nephritis]],  
|bgcolor="Beige"| [[Interstitial nephritis]], [[Eosinophilic cystitis ]], [[Hemodialysis ]], [[CRF not on renal replacement therapy ]], [[Diffuse proliferative glomerular  nephritis ]], [[Thrombotic thrombocytopenic purpura ]], [[Renal cell carcinoma]]
[[Interstitial  nephritis ]]
 
[[Eosinophilic cystitis ]]
 
[[Hemodialysis ]]
 
[[CRF not on renal replacement therapy ]]
 
[[Diffuse proliferative glomerular  nephritis ]]
 
[[Thrombotic thrombocytopenic purpura ]]
 
[[Renal cell carcinoma]]


|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''   
| '''Rheum / Immune / Allergy'''   
|bgcolor="Beige"| [[Eosinophilia-myalgia syndrome]],  
|bgcolor="Beige"| [[Eosinophilia-myalgia syndrome]],[[Hyper-IgE  syndrome ]], [[IgA deficiency ]], [[Wiskott-Aldrich syndrome  ]],[[Graft versus host immunologic reactions  ]],[[Milk protein allergy ]], [[Omenn syndrome ]], [[Severe congenital Neutropenia ]]
[[Hyper-IgE  syndrome ]]
 
[[IgA deficiency ]]
 
[[Wiskott-Aldrich syndrome  ]]
 
[[Graft versus host immunologic reactions  ]]
 
[[Milk protein allergy ]]
 
[[Omenn syndrome ]]
 
[[Severe congenital Neutropenia ]]


|-
|-
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|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| [[Angiolymphoid hyperplasia with eosinophilia]], [[cellulitis|Eosinophilic cellulitis]], [[Hypereosinophilic syndrome]], [[Kimura disease]]
|bgcolor="Beige"| [[Angiolymphoid hyperplasia with eosinophilia]], [[cellulitis|Eosinophilic cellulitis]], [[Hypereosinophilic syndrome]], [[Kimura disease]], [[Familial  eosinophilia ]], [[Episodic angioedema with  eosinophilia  ]], [[Aggressive systemic mastocytosis ]]
[[Familial  eosinophilia ]]
[[Episodic angioedema with  eosinophilia  ]]
[[Aggressive systemic mastocytosis ]]
|-
|-
|}
|}

Revision as of 17:04, 27 August 2012

Eosinophilia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

  • Eosinphilia refers to a group of idiopathic, neoplastic, infectious and allergic illnesses
  • Eosinphilia is associated with abnormally high number of eosinphil granulocytes in the serum and/or tissue
  • Reference range: 0-450 ul

Differential Diagnosis of Causes of Eosinophilia

By Organ System

Cardiovascular Endomyocardial fibrosis, Cholesterol embolism, Loeffler endocarditis , Eosinophilic myocarditis
Chemical / poisoning No underlying causes
Dermatologic Erythema multiforme, Atopic dermatitis, Dermatitis herpetiformis, Eosinophilic fasciitis, Eosinophilic pustular folliculitis, Pemphigus vulgaris, Psoriasis, Systemic lupus erythematosus, Sarcoptes scabiei, Eczema , Exfoliative dermatitis , Urticaria , Eosinophilic panniculitis , Shulman’s syndrome , Stevens - Johnson syndrome , Duhring disease , Histiositosis with Cutaneous involvement
Drug Side Effect Sulphonamides, Allopurinol, Amitriptyline, Capreomycin, Caspofungin, Chlorpropamide, Clomipramine, Daptomycin, Desipramine, Dothiepin, Doxycycline, Enfuvirtide, Etravirine, Gold salts, Granulocyte-macrophage colony stimulating factor, Hydralazine, Imipramine, Interleukin 2, Micafungin, Minocycline, Nalidixic acid, Nitrofurantoin, Nortriptyline, Olanzapine, Oxytetracycline, Pentostatin, Procarbazine, Tobacco smoking, Tryptophan, Vancomycin, Aldesleukin , Amikacin Sulfate , Capastat Sulfate , Capreomycin Sulfate , Cefotaxime Sodium , Cefoxitin Sodium , Ceftazidime , Cefuroxime , LyphocinMaolate
Ear Nose Throat No underlying causes
Endocrine Adrenal cortex insufficiency, Addisons disease , Adrenocortical insufficiency
Environmental An allergic reaction to an environmental antigen
Gastroenterologic Inflammatory Bowel Disease , Cirrhosis of liver , Chronic active hepatitis , Eosinophilic Gastroenteritis , Peritoneal dialysis
Genetic Autoimmune lymphoproliferative syndrome type 1, Autoimmune lymphoproliferative syndrome type 2, Familial eosinophilia, Kostmann disease, Omenn syndrome, Wiskott-Aldrich syndrome, TAR syndrome, kostmann syndrome, chromosome 21 partial deletion
Hematologic Acute lymphoblastic leukemia, Chronic myeloid leukaemia, Hodgkin lymphoma, Thrombocytopenia with absent radii , Familial reticuloendotheliosis with eosinophilia
Iatrogenic Radiotherapy
Infectious Disease Acanthocheilonemiasis, Alveolar hydatid disease, Ancylostoma caninum, Ancylostoma duodenale, Angiostrongyliasis, Anisakiasis, Ascariasis, Capillaria, Clonorchiasis, Coccidioidomycosis, Dicrocoelium dendriticum fluke, Dracunculiasis, Echinococcus granulosus, Fasciola hepatica, Gnathostomiasis, Heterophyiasis, Lepromatous leprosy, Loa loa filariasis, Lymphatic filariasis, Mansonelliasis, Metagonimiasis, Mycobacterium tuberculosis, Onchocerciasis, Opisthorchiasis, Paragonimiasis, Schistosoma haematobium, Schistosoma mansoni, Strongyloidiasis, Toxocariasis, Trichinella spiralis, Pneumocystis jirovecii infection , Visceral larva migrans , Brucellosis , Cat-scratch fever , Chlamydial pneumonia of infancy , Infectious lymphocytosis , Infectious mononucleosis , Scarlet fever, Amebiasis , Malaria
Musculoskeletal / Ortho Polyarteritis nodosa, Polymyositis, Rheumatoid disease, Dressler's syndrome , Eosinophilic fasciitis , Idiopathic eosinophilic synovitis , Progressive systemic sclerosis (scleroderma) , SLE , Sjögren's syndrome , Sarcoidosis , Eosinophilia – Myalgia syndrome , Dermatomyositis
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Acute lymphoblastic leukemia, Chronic myeloid leukaemia, Hodgkin lymphoma, Immunoblastic lymphadenopathy , Sarcomas and carcinomas of Ovary, Carcinoma of Pancreas , Carcinoma of Lung , Carcinoma of colon, Carcinoma of cervix , Acute eosinophilic leukemia , Chronic eosinophilic leukemia , Brain Tumors
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Simple pulmonary eosinophilia, Visceral larva migrans, Allergic bronchopulmonary aspergillosis, Extrinsic allergic alveolitis, Tropical pulmonary eosinophilia, Churg-Strauss syndrome, Bronchial asthma, Allergic Rhinitis, Chronic eosinophilic pneumonia , Occupational lung diseases , Idiopathic eosinophilic chronic pneumopathy , Magrassi- Leonardi syndrome
Renal / Electrolyte Interstitial nephritis, Eosinophilic cystitis , Hemodialysis , CRF not on renal replacement therapy , Diffuse proliferative glomerular nephritis , Thrombotic thrombocytopenic purpura , Renal cell carcinoma
Rheum / Immune / Allergy Eosinophilia-myalgia syndrome,Hyper-IgE syndrome , IgA deficiency , Wiskott-Aldrich syndrome ,Graft versus host immunologic reactions ,Milk protein allergy , Omenn syndrome , Severe congenital Neutropenia
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Angiolymphoid hyperplasia with eosinophilia, Eosinophilic cellulitis, Hypereosinophilic syndrome, Kimura disease, Familial eosinophilia , Episodic angioedema with eosinophilia , Aggressive systemic mastocytosis

In alphabetical order [1]

Related Chapters

References

  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:127-128 ISBN 1591032016


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