Cav1.3

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Calcium channel, voltage-dependent, L type, alpha 1D subunit
PDB rendering based on 2be6.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols CACNA1D ; CACH3; CACN4; CACNL1A2; CCHL1A2; Cav1.3
External IDs Template:OMIM5 Template:MGI HomoloGene578
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Cav1.3 also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene.[1]


See also

References

  1. "Entrez Gene: CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit".

Further reading

  • Williams ME, Feldman DH, McCue AF; et al. (1992). "Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype". Neuron. 8 (1): 71–84. PMID 1309651.
  • Seino S, Chen L, Seino M; et al. (1992). "Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells". Proc. Natl. Acad. Sci. U.S.A. 89 (2): 584–8. PMID 1309948.
  • Seino S, Yamada Y, Espinosa R; et al. (1992). "Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3". Genomics. 13 (4): 1375–7. PMID 1324226.
  • Chin HM, Kozak CA, Kim HL; et al. (1992). "A brain L-type calcium channel alpha 1 subunit gene (CCHL1A2) maps to mouse chromosome 14 and human chromosome 3". Genomics. 11 (4): 914–9. PMID 1664412.
  • Mori Y, Friedrich T, Kim MS; et al. (1991). "Primary structure and functional expression from complementary DNA of a brain calcium channel". Nature. 350 (6317): 398–402. doi:10.1038/350398a0. PMID 1849233.
  • Yamada Y, Masuda K, Li Q; et al. (1995). "The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes". Genomics. 27 (2): 312–9. doi:10.1006/geno.1995.1048. PMID 7557998.
  • Puro DG, Hwang JJ, Kwon OJ, Chin H (1996). "Characterization of an L-type calcium channel expressed by human retinal Müller (glial) cells". Brain Res. Mol. Brain Res. 37 (1–2): 41–8. PMID 8738134.
  • Yang SN, Larsson O, Bränström R; et al. (1999). "Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells". Proc. Natl. Acad. Sci. U.S.A. 96 (18): 10164–9. PMID 10468580.
  • Bell DC, Butcher AJ, Berrow NS; et al. (2001). "Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents". J. Neurophysiol. 85 (2): 816–27. PMID 11160515.
  • Rosenthal R, Thieme H, Strauss O (2001). "Fibroblast growth factor receptor 2 (FGFR2) in brain neurons and retinal pigment epithelial cells act via stimulation of neuroendocrine L-type channels (Ca(v)1.3)". FASEB J. 15 (6): 970–7. PMID 11292657.
  • Davare MA, Avdonin V, Hall DD; et al. (2001). "A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2". Science. 293 (5527): 98–101. doi:10.1126/science.293.5527.98. PMID 11441182.
  • Namkung Y, Skrypnyk N, Jeong MJ; et al. (2001). "Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation". J. Clin. Invest. 108 (7): 1015–22. PMID 11581302.
  • Stokes L, Gordon J, Grafton G (2004). "Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits". J. Biol. Chem. 279 (19): 19566–73. doi:10.1074/jbc.M401481200. PMID 14981074.
  • Qu Y, Baroudi G, Yue Y, Boutjdir M (2006). "Novel molecular mechanism involving alpha1D (Cav1.3) L-type calcium channel in autoimmune-associated sinus bradycardia". Circulation. 111 (23): 3034–41. doi:10.1161/CIRCULATIONAHA.104.517326. PMID 15939813.
  • Baroudi G, Qu Y, Ramadan O; et al. (2006). "Protein kinase C activation inhibits Cav1.3 calcium channel at NH2-terminal serine 81 phosphorylation site". Am. J. Physiol. Heart Circ. Physiol. 291 (4): H1614–22. doi:10.1152/ajpheart.00095.2006. PMID 16973824.
  • Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.