CLCN3: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Latest revision as of 09:45, 30 August 2017

H⁺/Cl⁻ exchange transporter 3 is a protein that in humans is encoded by the CLCN3 gene.^[1]

Interactions

CLCN3 has been shown to interact with PDZK1.^[2]

References

↑ "Entrez Gene: CLCN3 chloride channel 3".
↑ Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR (Feb 2003). "The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins". J. Biol. Chem. 278 (8): 6440–9. doi:10.1074/jbc.M211050200. PMID 12471024.

Borsani G, Rugarli EI, Taglialatela M, Wong C, Ballabio A (1995). "Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein". Genomics. 27 (1): 131–41. doi:10.1006/geno.1995.1015. PMID 7665160.
Taine L, Coupry I, Boisseau P, Saura R, Lacombe D, Arveiler B (1998). "Refined localisation of the voltage-gated chloride channel, CLCN3, to 4q33". Hum. Genet. 102 (2): 178–81. doi:10.1007/s004390050673. PMID 9521585.
Shepard AR, Rae JL (1998). "Ion transporters and receptors in cDNA libraries from lens and cornea epithelia". Curr. Eye Res. 17 (7): 708–19. doi:10.1080/02713689808951247. PMID 9678416.
Loo MA, Jensen TJ, Cui L, Hou Y, Chang XB, Riordan JR (1998). "Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome". EMBO J. 17 (23): 6879–87. doi:10.1093/emboj/17.23.6879. PMC 1171036. PMID 9843494.
Lamb FS, Clayton GH, Liu BX, Smith RL, Barna TJ, Schutte BC (1999). "Expression of CLCN voltage-gated chloride channel genes in human blood vessels". J. Mol. Cell. Cardiol. 31 (3): 657–66. doi:10.1006/jmcc.1998.0901. PMID 10198195.
Hartley JL, Temple GF, Brasch MA (2000). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Huang P, Liu J, Di A, Robinson NC, Musch MW, Kaetzel MA, Nelson DJ (2001). "Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase". J. Biol. Chem. 276 (23): 20093–100. doi:10.1074/jbc.M009376200. PMID 11274166.
Lamb FS, Graeff RW, Clayton GH, Smith RL, Schutte BC, McCray PB (2001). "Ontogeny of CLCN3 chloride channel gene expression in human pulmonary epithelium". Am. J. Respir. Cell Mol. Biol. 24 (4): 376–81. doi:10.1165/ajrcmb.24.4.4114. PMID 11306429.
Ogura T, Furukawa T, Toyozaki T, Yamada K, Zheng YJ, Katayama Y, Nakaya H, Inagaki N (2002). "ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC". FASEB J. 16 (8): 863–5. doi:10.1096/fj.01-0845fje. PMID 11967229.
Hermoso M, Satterwhite CM, Andrade YN, Hidalgo J, Wilson SM, Horowitz B, Hume JR (2002). "ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes". J. Biol. Chem. 277 (42): 40066–74. doi:10.1074/jbc.M205132200. PMID 12183454.
Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR (2003). "The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins". J. Biol. Chem. 278 (8): 6440–9. doi:10.1074/jbc.M211050200. PMID 12471024.
Jin NG, Kim JK, Yang DK, Cho SJ, Kim JM, Koh EJ, Jung HC, So I, Kim KW (2003). "Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (5): G938–48. doi:10.1152/ajpgi.00470.2002. PMID 12842831.
Olsen ML, Schade S, Lyons SA, Amaral MD, Sontheimer H (2003). "Expression of voltage-gated chloride channels in human glioma cells". J. Neurosci. 23 (13): 5572–82. PMID 12843258.
Salazar G, Love R, Styers ML, Werner E, Peden A, Rodriguez S, Gearing M, Wainer BH, Faundez V (2004). "AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells". J. Biol. Chem. 279 (24): 25430–9. doi:10.1074/jbc.M402331200. PMID 15073168.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Zhou JG, Ren JL, Qiu QY, He H, Guan YY (2005). "Regulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells". J. Biol. Chem. 280 (8): 7301–8. doi:10.1074/jbc.M412813200. PMID 15596438.
Yeung CH, Barfield JP, Cooper TG (2005). "Chloride channels in physiological volume regulation of human spermatozoa". Biol. Reprod. 73 (5): 1057–63. doi:10.1095/biolreprod.105.044123. PMID 16033995.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

External links

CLCN3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
Human CLCN3 genome location and CLCN3 gene details page in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: CLCN3 chloride channel 3".

[pmid12471024-2] Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR (Feb 2003). "The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins". J. Biol. Chem. 278 (8): 6440–9. doi:10.1074/jbc.M211050200. PMID 12471024.

[1]

[2]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''H<sup>+</sup>/Cl<sup>−</sup> exchange transporter 3''' is a [[protein]] that in humans is encoded by the ''CLCN3'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLCN3 chloride channel 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1182| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Chloride channel 3
- | HGNCid = 2021
- | Symbol = CLCN3
- | AltSymbols =; CLC3; ClC-3
- | OMIM = 600580
- | ECnumber =
- | Homologene = 20435
- | MGIid = 103555
- | GeneAtlas_image1 = PBB_GE_CLCN3_201734_at_tn.png
- | GeneAtlas_image2 = PBB_GE_CLCN3_201732_s_at_tn.png
- | GeneAtlas_image3 = PBB_GE_CLCN3_201733_at_tn.png
- | Function = {{GNF_GO|id=GO:0005247 |text = voltage-gated chloride channel activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0030165 |text = PDZ domain binding}} {{GNF_GO|id=GO:0031404 |text = chloride ion binding}} {{GNF_GO|id=GO:0042803 |text = protein homodimerization activity}} {{GNF_GO|id=GO:0046982 |text = protein heterodimerization activity}}
- | Component = {{GNF_GO|id=GO:0005769 |text = early endosome}} {{GNF_GO|id=GO:0005770 |text = late endosome}} {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF_GO|id=GO:0009986 |text = cell surface}} {{GNF_GO|id=GO:0012506 |text = vesicle membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0006811 |text = ion transport}} {{GNF_GO|id=GO:0006821 |text = chloride transport}} {{GNF_GO|id=GO:0006885 |text = regulation of pH}} {{GNF_GO|id=GO:0048388 |text = endosomal lumen acidification}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 1182
-    | Hs_Ensembl = ENSG00000109572
-    | Hs_RefseqProtein = NP_001820
-    | Hs_RefseqmRNA = NM_001829
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 4
-    | Hs_GenLoc_start = 170778297
-    | Hs_GenLoc_end = 170878731
-    | Hs_Uniprot = P51790
-    | Mm_EntrezGene = 12725
-    | Mm_Ensembl = ENSMUSG00000004319
-    | Mm_RefseqmRNA = NM_007711
-    | Mm_RefseqProtein = NP_031737
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 8
-    | Mm_GenLoc_start = 63802531
-    | Mm_GenLoc_end = 63875442
-    | Mm_Uniprot = Q6PEV2
-  }}
-}}
-'''Chloride channel 3''', also known as '''CLCN3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLCN3 chloride channel 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1182| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+CLCN3 has been shown to [[Protein-protein interaction|interact]] with [[PDZK1]].<ref name=pmid12471024>{{cite journal | vauthors = Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR | title = The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins | journal = J. Biol. Chem. | volume = 278 | issue = 8 | pages = 6440–9  | date = Feb 2003 | pmid = 12471024 | doi = 10.1074/jbc.M211050200 }}</ref>
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+== See also ==
-{{reflist|2}}
+* [[Chloride channel]]
-==Further reading==
+== References ==
+{{reflist}}
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Borsani G, Rugarli EI, Taglialatela M, Wong C, Ballabio A | title = Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein | journal = Genomics | volume = 27 | issue = 1 | pages = 131–41 | year = 1995 | pmid = 7665160 | doi = 10.1006/geno.1995.1015 }}
-| citations =
+* {{cite journal | vauthors = Taine L, Coupry I, Boisseau P, Saura R, Lacombe D, Arveiler B | title = Refined localisation of the voltage-gated chloride channel, CLCN3, to 4q33 | journal = Hum. Genet. | volume = 102 | issue = 2 | pages = 178–81 | year = 1998 | pmid = 9521585 | doi = 10.1007/s004390050673 }}
-*{{cite journal  | author=Borsani G, Rugarli EI, Taglialatela M, ''et al.'' |title=Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein. |journal=Genomics |volume=27 |issue= 1 |pages= 131-41 |year= 1995 |pmid= 7665160 |doi= 10.1006/geno.1995.1015 }}
+* {{cite journal | vauthors = Shepard AR, Rae JL | title = Ion transporters and receptors in cDNA libraries from lens and cornea epithelia | journal = Curr. Eye Res. | volume = 17 | issue = 7 | pages = 708–19 | year = 1998 | pmid = 9678416 | doi = 10.1080/02713689808951247 }}
-*{{cite journal  | author=Taine L, Coupry I, Boisseau P, ''et al.'' |title=Refined localisation of the voltage-gated chloride channel, CLCN3, to 4q33. |journal=Hum. Genet. |volume=102 |issue= 2 |pages= 178-81 |year= 1998 |pmid= 9521585 |doi=  }}
+* {{cite journal | vauthors = Loo MA, Jensen TJ, Cui L, Hou Y, Chang XB, Riordan JR | title = Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome | journal = EMBO J. | volume = 17 | issue = 23 | pages = 6879–87 | year = 1998 | pmid = 9843494 | pmc = 1171036 | doi = 10.1093/emboj/17.23.6879 }}
-*{{cite journal  | author=Shepard AR, Rae JL |title=Ion transporters and receptors in cDNA libraries from lens and cornea epithelia. |journal=Curr. Eye Res. |volume=17 |issue= 7 |pages= 708-19 |year= 1998 |pmid= 9678416 |doi=  }}
+* {{cite journal | vauthors = Lamb FS, Clayton GH, Liu BX, Smith RL, Barna TJ, Schutte BC | title = Expression of CLCN voltage-gated chloride channel genes in human blood vessels | journal = J. Mol. Cell. Cardiol. | volume = 31 | issue = 3 | pages = 657–66 | year = 1999 | pmid = 10198195 | doi = 10.1006/jmcc.1998.0901 }}
-*{{cite journal  | author=Loo MA, Jensen TJ, Cui L, ''et al.'' |title=Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. |journal=EMBO J. |volume=17 |issue= 23 |pages= 6879-87 |year= 1999 |pmid= 9843494 |doi= 10.1093/emboj/17.23.6879 }}
+* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Res. | volume = 10 | issue = 11 | pages = 1788–95 | year = 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
-*{{cite journal  | author=Lamb FS, Clayton GH, Liu BX, ''et al.'' |title=Expression of CLCN voltage-gated chloride channel genes in human blood vessels. |journal=J. Mol. Cell. Cardiol. |volume=31 |issue= 3 |pages= 657-66 |year= 1999 |pmid= 10198195 |doi= 10.1006/jmcc.1998.0901 }}
+* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Res. | volume = 11 | issue = 3 | pages = 422–35 | year = 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
+* {{cite journal | vauthors = Huang P, Liu J, Di A, Robinson NC, Musch MW, Kaetzel MA, Nelson DJ | title = Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase | journal = J. Biol. Chem. | volume = 276 | issue = 23 | pages = 20093–100 | year = 2001 | pmid = 11274166 | doi = 10.1074/jbc.M009376200 }}
-*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
+* {{cite journal | vauthors = Lamb FS, Graeff RW, Clayton GH, Smith RL, Schutte BC, McCray PB | title = Ontogeny of CLCN3 chloride channel gene expression in human pulmonary epithelium | journal = Am. J. Respir. Cell Mol. Biol. | volume = 24 | issue = 4 | pages = 376–81 | year = 2001 | pmid = 11306429 | doi = 10.1165/ajrcmb.24.4.4114 }}
-*{{cite journal  | author=Huang P, Liu J, Di A, ''et al.'' |title=Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 20093-100 |year= 2001 |pmid= 11274166 |doi= 10.1074/jbc.M009376200 }}
+* {{cite journal | vauthors = Ogura T, Furukawa T, Toyozaki T, Yamada K, Zheng YJ, Katayama Y, Nakaya H, Inagaki N | title = ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC | journal = FASEB J. | volume = 16 | issue = 8 | pages = 863–5 | year = 2002 | pmid = 11967229 | doi = 10.1096/fj.01-0845fje }}
-*{{cite journal  | author=Lamb FS, Graeff RW, Clayton GH, ''et al.'' |title=Ontogeny of CLCN3 chloride channel gene expression in human pulmonary epithelium. |journal=Am. J. Respir. Cell Mol. Biol. |volume=24 |issue= 4 |pages= 376-81 |year= 2001 |pmid= 11306429 |doi=  }}
+* {{cite journal | vauthors = Hermoso M, Satterwhite CM, Andrade YN, Hidalgo J, Wilson SM, Horowitz B, Hume JR | title = ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes | journal = J. Biol. Chem. | volume = 277 | issue = 42 | pages = 40066–74 | year = 2002 | pmid = 12183454 | doi = 10.1074/jbc.M205132200 }}
-*{{cite journal  | author=Ogura T, Furukawa T, Toyozaki T, ''et al.'' |title=ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC. |journal=FASEB J. |volume=16 |issue= 8 |pages= 863-5 |year= 2002 |pmid= 11967229 |doi= 10.1096/fj.01-0845fje }}
+* {{cite journal | vauthors = Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR | title = The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins | journal = J. Biol. Chem. | volume = 278 | issue = 8 | pages = 6440–9 | year = 2003 | pmid = 12471024 | doi = 10.1074/jbc.M211050200 }}
-*{{cite journal  | author=Hermoso M, Satterwhite CM, Andrade YN, ''et al.'' |title=ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes. |journal=J. Biol. Chem. |volume=277 |issue= 42 |pages= 40066-74 |year= 2002 |pmid= 12183454 |doi= 10.1074/jbc.M205132200 }}
+* {{cite journal | vauthors = Jin NG, Kim JK, Yang DK, Cho SJ, Kim JM, Koh EJ, Jung HC, So I, Kim KW | title = Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells | journal = Am. J. Physiol. Gastrointest. Liver Physiol. | volume = 285 | issue = 5 | pages = G938-48 | year = 2003 | pmid = 12842831 | doi = 10.1152/ajpgi.00470.2002 }}
-*{{cite journal  | author=Gentzsch M, Cui L, Mengos A, ''et al.'' |title=The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins. |journal=J. Biol. Chem. |volume=278 |issue= 8 |pages= 6440-9 |year= 2003 |pmid= 12471024 |doi= 10.1074/jbc.M211050200 }}
+* {{cite journal | vauthors = Olsen ML, Schade S, Lyons SA, Amaral MD, Sontheimer H | title = Expression of voltage-gated chloride channels in human glioma cells | journal = J. Neurosci. | volume = 23 | issue = 13 | pages = 5572–82 | year = 2003 | pmid = 12843258 | doi =  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+* {{cite journal | vauthors = Salazar G, Love R, Styers ML, Werner E, Peden A, Rodriguez S, Gearing M, Wainer BH, Faundez V | title = AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells | journal = J. Biol. Chem. | volume = 279 | issue = 24 | pages = 25430–9 | year = 2004 | pmid = 15073168 | doi = 10.1074/jbc.M402331200 }}
-*{{cite journal  | author=Jin NG, Kim JK, Yang DK, ''et al.'' |title=Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=285 |issue= 5 |pages= G938-48 |year= 2003 |pmid= 12842831 |doi= 10.1152/ajpgi.00470.2002 }}
+* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Res. | volume = 14 | issue = 10B | pages = 2136–44 | year = 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
-*{{cite journal  | author=Olsen ML, Schade S, Lyons SA, ''et al.'' |title=Expression of voltage-gated chloride channels in human glioma cells. |journal=J. Neurosci. |volume=23 |issue= 13 |pages= 5572-82 |year= 2003 |pmid= 12843258 |doi=  }}
+* {{cite journal | vauthors = Zhou JG, Ren JL, Qiu QY, He H, Guan YY | title = Regulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells | journal = J. Biol. Chem. | volume = 280 | issue = 8 | pages = 7301–8 | year = 2005 | pmid = 15596438 | doi = 10.1074/jbc.M412813200 }}
-*{{cite journal  | author=Salazar G, Love R, Styers ML, ''et al.'' |title=AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells. |journal=J. Biol. Chem. |volume=279 |issue= 24 |pages= 25430-9 |year= 2004 |pmid= 15073168 |doi= 10.1074/jbc.M402331200 }}
+* {{cite journal | vauthors = Yeung CH, Barfield JP, Cooper TG | title = Chloride channels in physiological volume regulation of human spermatozoa | journal = Biol. Reprod. | volume = 73 | issue = 5 | pages = 1057–63 | year = 2005 | pmid = 16033995 | doi = 10.1095/biolreprod.105.044123 }}
-*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
+* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D415-8 | year = 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
-*{{cite journal  | author=Zhou JG, Ren JL, Qiu QY, ''et al.'' |title=Regulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells. |journal=J. Biol. Chem. |volume=280 |issue= 8 |pages= 7301-8 |year= 2005 |pmid= 15596438 |doi= 10.1074/jbc.M412813200 }}
-*{{cite journal  | author=Yeung CH, Barfield JP, Cooper TG |title=Chloride channels in physiological volume regulation of human spermatozoa. |journal=Biol. Reprod. |volume=73 |issue= 5 |pages= 1057-63 |year= 2006 |pmid= 16033995 |doi= 10.1095/biolreprod.105.044123 }}
-*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
-}}
 {{refend}}
-{{protein-stub}}
+== External links ==
-{{WikiDoc Sources}}
+* {{MeshName|CLCN3+protein,+human}}
+* {{UCSC gene info|CLCN3}}
+{{NLM content}}
+{{Ion channels|g4}}
+[[Category:Ion channels]]
+{{gene-4-stub}}

CLCN3: Difference between revisions

Latest revision as of 09:45, 30 August 2017

Contents

Interactions

See also

References

Further reading

External links

Navigation menu