Teratoma
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Teratoma Microchapters |
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Teratoma On the Web |
American Roentgen Ray Society Images of Teratoma |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Michael Maddaleni, B.S.
Overview
Historical Perspective
Pathophysiology
Epidemiology & Demographics
Risk Factors
Screening
Causes
Differentiating Teratoma
Complications & Prognosis
Diagnosis
History and Symptoms | Physical Examination | Staging | Laboratory tests | Electrocardiogram | X Rays | CT | MRI Echocardiography or Ultrasound | Other images | Alternative diagnostics
Treatment
Medical therapy | Surgical options | Primary prevention | Secondary prevention | Financial costs | Future therapies
Treatment
Chemotherapy
For malignant teratomas, usually, surgery is followed by chemotherapy.
Teratomas that are in surgically inaccessible locations, or are very complex, or are likely to be malignant (due to late discovery and/or treatment) sometimes are treated first with chemotherapy.
Clinical trials
There are now (2007) two clinical trials in progress that address germ cell tumors, both of which include teratomas.[1][2]
Use in basic research
In light of the ethical issues surrounding the source of human stem cells, teratomas are being looked at as an alternative source for research since they lack the potential to grow into functional human beings.
References
- ↑ GCT1P1 Protocol / Clinical Study: Pilot study of Cisplatin, Etoposide, Bleomycin and Escalating Dose Cyclophosphamide Therapy for Children with High-Risk Malignant Germ Cell Tumors
- ↑ GCT132 Protocol / Clinical Study: A Phase III Study of Reduced Therapy in the Treatment of Children with Low and Intermediate Risk Extracranial Germ Cell Tumors (AGCT0132)
See also
Tumor pages for locations in which teratoma can occur:
Other conditions that may resemble a teratoma:
- Pilonidal cyst in humans
Technical information
- Orphanet page on teratoma
- EMedicine article on cystic teratoma (also search EMedicine for all articles containing the word teratoma)
- Monster Tumors Show Scientific Potential in War Against Cancer article in the New York Times
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