Sandbox:Sharmi

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Differentiating diagnosis of Lymphoma Symptoms Signs Diagnosis Additional Findings
Fever Rash Diarrhea Abdominal pain Weight loss Painful lymphadenopathy Hepatosplenomegaly Arthritis Lab Findings
Autoimmune lymphoproliferative syndrome
Lymphoma + + + + Increase ESR, increased LDH Night sweats, constant fatigue
Brucellosis + + + + + + + Relative lymphocytosis Night sweats, often with characteristic smell, likened to wet hay
Typhoid fever + + + + + Decreased hemoglobin Incremental increase in temperature initially and than sustained fever as high as 40°C (104°F)
Malaria + + + + + Microcytosis,

elevated LDH

"Tertian" fever: paroxysms occur every second day
Tuberculosis + + + + + + Mild normocytic anemiahyponatremia, and

hypercalcemia

Night sweats, constant fatigue
Mumps + + Relative lymphocytosis, serum amylaseelevated Parotidswelling/tenderness
Rheumatoid arthritis + + ESR and CRP elevated, positive rheumatoid factor Morning stiffness
SLE + + + + ESR and CRP elevated, positive ANA Fatigue
HIV + + + + Leukopenia Constant fatigue


Disease Differentiating signs and symptoms Differentiating tests
Autoimmune lymphoproliferative syndrome
CNS lymphoma
Disseminated tuberculosis
Aspergillosis
Cryptococcosis
Chagas disease
CMV infection
HSV infection
Varicella Zoster infection
Brain abscess
Progressive multifocal leukoencephalopathy
  • Symptoms are often more insidious in onset and progress over months. Symptoms include progressive weakness, poor coordination, with gradual slowing of mental function. Only seen in the immunosuppressed. Rarely associated with fever or other systemic symptoms