Low chylomicron remnant causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Low chylomicron remnant can be caused by various factors, with malabsorption and hyperthyroidism[1] being the most common. Genetic, drug side effect, and gastroenterologic disease were also reported to cause low chylomicron remnant.
Low Chylomicron Remnant Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Low chylomicron remnant in itself is not a life threatening condition.
Common Causes
- Abetalipoproteinemia[2]
- Chylomicron retention disease
- Hyperthyroidism [1]
- Intestinal lymphangiectasia
- Lomitapide
- Malabsorption
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Lomitapide |
| Ear Nose Throat | No underlying causes |
| Endocrine | Hyperthyroidism |
| Environmental | No underlying causes |
| Gastroenterologic | Intestinal lymphangiectasia, malabsorption |
| Genetic | Abetalipoproteinemia[2], chylomicron retention disease |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | Malabsorption |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes by Alphabetical Order
- Abetalipoproteinemia[2]
- Chylomicron retention disease
- Hyperthyroidism [1]
- Intestinal lymphangiectasia
- Lomitapide
- Malabsorption
References
- ↑ 1.0 1.1 1.2 Weintraub M, Grosskopf I, Trostanesky Y, Charach G, Rubinstein A, Stern N (1999). "Thyroxine replacement therapy enhances clearance of chylomicron remnants in patients with hypothyroidism". J Clin Endocrinol Metab. 84 (7): 2532–6. PMID 10404832.
- ↑ 2.0 2.1 2.2 Wetterau JR, Aggerbeck LP, Bouma ME, Eisenberg C, Munck A, Hermier M; et al. (1992). "Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia". Science. 258 (5084): 999–1001. PMID 1439810.