Low density lipoprotein receptor-related protein 8

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Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Identifiers
SymbolLRP8; ApoER2
Entrez7804
HUGO6700
OMIM602600
RefSeqNM_004631
UniProtQ14114
Other data
LocusChr. 1 p32.3

Low density lipoprotein receptor-related protein 8, or LRP8 (also Apolipoprotein E Receptor 2; ApoER2) is a member of the LDL receptor family that plays a role in endocytosis and signal transduction. Together with VLDLR it is able to bind reelin, leading to the phosphorylation of DAB1, which binds on its cytosolic tail.

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