Cobamamide

Cobamamide

Gene therapy
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B03BA04 (WHO)
Physiological data
Legal status
Legal status	US: OTC
Pharmacokinetic data
Identifiers
IUPAC name Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ- (5'-deoxy-5'-adenosyl)cobamide
CAS Number	13870-90-1 Y
PubChem Template:Abbreviation	5459907
ChemSpider	16736117 Y
KEGG	D00042 Y
ChEBI	CHEBI:18408 N
Chemical and physical data
Formula	C72H100CoN18O17P
Molar mass	1579.58 g/mol
InChI InChI=1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-2/t31?,34?,35?,36?,37?,41-,52-,53-,56?,57+,59?,60?,61?,62?;4-,6-,7-,10-;/m11./s1 Y Key:ZIHHMGTYZOSFRC-CXGXMSGESA-L Y
Template:XmarkY (what is this?)  (verify)

WikiDoc Resources for Cobamamide
Articles
Most recent articles on Cobamamide Most cited articles on Cobamamide Review articles on Cobamamide Articles on Cobamamide in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Cobamamide Images of Cobamamide Photos of Cobamamide Podcasts & MP3s on Cobamamide Videos on Cobamamide
Evidence Based Medicine
Cochrane Collaboration on Cobamamide Bandolier on Cobamamide TRIP on Cobamamide
Clinical Trials
Ongoing Trials on Cobamamide at Clinical Trials.gov Trial results on Cobamamide Clinical Trials on Cobamamide at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Cobamamide NICE Guidance on Cobamamide NHS PRODIGY Guidance FDA on Cobamamide CDC on Cobamamide
Books
Books on Cobamamide
News
Cobamamide in the news Be alerted to news on Cobamamide News trends on Cobamamide
Commentary
Blogs on Cobamamide
Definitions
Definitions of Cobamamide
Patient Resources / Community
Patient resources on Cobamamide Discussion groups on Cobamamide Patient Handouts on Cobamamide Directions to Hospitals Treating Cobamamide Risk calculators and risk factors for Cobamamide
Healthcare Provider Resources
Symptoms of Cobamamide Causes & Risk Factors for Cobamamide Diagnostic studies for Cobamamide Treatment of Cobamamide
Continuing Medical Education (CME)
CME Programs on Cobamamide
International
Cobamamide en Espanol Cobamamide en Francais
Business
Cobamamide in the Marketplace Patents on Cobamamide
Experimental / Informatics
List of terms related to Cobamamide

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cobamamide (AdoCbl), which is also known as adenosylcobalamin and dibencozide, is, along with methylcobalamin (MeCbl), one of the active forms of vitamin B₁₂. As a nutritional supplement, it is available in tabletted form, but unlike cyanocobalamin, methylcobalamin, and hydroxocobalamin, it is not available in injectable form.

An enzyme that uses adenosylcobalamin as a cofactor is methylmalonyl-CoA mutase (MCM).

External links

• B03BA04 (WHO)