|Other names||25-Hydroxyvitamin D3|
3D model (JSmol)
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|Molar mass||400.637 g/mol|
|Except where noted otherwise, data are given for|
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references
Calcidiol, calcifediol, 25-hydroxycholecalciferol, or 25–hydroxy–vitamin D, is a prehormone which is produced by the metabolism of vitamin D3 (cholecalciferol) and which is converted by the kidneys (via 25-Hydroxyvitamin D3 1-alpha-Hydroxylase) into calcitriol (1,25-vitamin D), a steroid hormone.
In medicine, bloodstream concentration of calcidiol is commonly used to measure overall vitamin D levels. Calcifediol promotes the mineralization of bones and teeth and is used to treat diseases caused by vitamin D deficiency such as rickets and osteomalacia. It is effective even in azotemic patients.
- Dietary Reference intakes for Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. Institute of Medicine, 1997
- Vitamin D Pharmacology at VitaminDCouncil.com