COVID-19-associated pericarditis

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For COVID-19 frequently asked inpatient questions, click here
For COVID-19 frequently asked outpatient questions, click here
For COVID-19 patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mounika Reddy Vadiyala, M.B.B.S.[2]

Synonyms and Keywords: Novel coronavirus, COVID-19, Wuhan coronavirus, coronavirus Disease-19, coronavirus disease 2019, SARS-CoV-2, COVID-19, COVID-19, 2019-nCoV, 2019 novel coronavirus, cardiovascular finding in COVID-19, pericardial injury in COVID-19, pericarditis, pericarditis in COVID-19, COVID-19-associated Pericarditis, SARS-CoV2-associated pericarditis, myocardial injury in COVID-19, COVID-19 pericarditis

Overview

COVID-19 caused by the novel coronavirus, also known as SARS-CoV-2 mainly affects the lungs, causing severe acute respiratory syndrome. It invades through the angiotensin-converting enzyme 2 (ACE2) receptors present abundantly not only in the lungs but also in the heart, kidneys, intestine, brain, skin thus causing multiorgan dysfunction. Studies have demonstrated that COVID-19 interacts with the cardiovascular system, thereby causing myocardial injury and dysfunction as well as increasing morbidity among patients with underlying cardiovascular conditions. Pericarditis in COVID-19 is a rare complication. Very few cases of COVID-19-associated pericarditis have been reported. Reports on large pericardial effusion and cardiac tamponade are rare in COVID-19.

Historical Perspective

Classification

Pathophysiology

Causes

Pericarditis in COVID-19 is likely caused by:

Differentiating COVID-19-associated pericarditis from other diseases

  • For further information about the differential diagnosis, click here.
  • For further information about the differential diagnosis of COVID-19, click here.

Epidemiology and Demographics

Age

Gender

  • There is no data on gender predilection to pericarditis in COVID-19.
  • The number of cases in females is more than males among the few cases reported.

Race

Natural History, Complications and Prognosis

Natural History

Complications

Common complications include:

Prognosis

Diagnosis

Symptoms

Physical Examination

Laboratory Findings

Inflammatory biomarkers

Cardiac biomarkers

Electrocardiogram

Imaging

Chest X-ray

Echocardiography

For echocardiography findings in pericarditis in general, click here.

CT scan

Cardiac magnetic resonance

Pericardial fluid analysis

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

References

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