Tricuspid atresia differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Sara Zand, M.D.[2] Keri Shafer, M.D. [3] Priyamvada Singh, MBBS [4]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [5]

Overview

Patients with tricuspid atresia should be differentiated from other cardiac causes of cyanosis and lung olygemia include:Tetralogy of Fallot, Truncus arteriosus, Total anomalous pulmonary venous connection, Pulmonary atresia, Tricuspid stenosis.

Differentiating tricuspid atresia from other Diseases

Patients with tricuspid atresia should be differentiated from other cardiac causes of cyanosis and lung olygemia include:


Table below compares cyanotic heart diseases:[1][2][3][4]

Disorders Etiology Clinical Presentation Laboratory Findings Electrocardiogram Findings Echocardiography Findings X-Ray Findings
Tetralogy of Fallot Multifactorial

Echocardiography may show:

  • Residual VSD or ASD
  • RV outflow tract obstruction
  • Abnormal valvular anatomy
  • The boot-shaped heart appearance
  • Normal heart size
  • Pulmonary vascular marking may be normal or decreased
Total Anomalous Pulmonary Venous Connection Multifactorial
  • Prominence of the pulmonary arteries
  • Mild enlargement of heart
  • The classic snowman sign is seen in supracardiac subtype
Tricuspid Atresia Multifactorial
  • Respiratory difficulties as nasal flaring or muscle retractions
  • Cyanosis
  • Growth retradation
  • Tall P waves indicate atrial enlargement.
  • Frontal plane QRS axis may be leftward.
Echocardiography may show
Transposition of the Great Arteries

Multifactorial

Echocardiography may show:

  • The classic egg on string appearance
  • Pulmonary vascular marking may be normal or increased

References

  1. Bailliard F, Anderson RH (January 2009). "Tetralogy of Fallot". Orphanet J Rare Dis. 4: 2. doi:10.1186/1750-1172-4-2. PMC 2651859. PMID 19144126.
  2. Kao CC, Hsieh CC, Cheng PJ, Chiang CH, Huang SY (2017). "Total Anomalous Pulmonary Venous Connection: From Embryology to a Prenatal Ultrasound Diagnostic Update". J Med Ultrasound. 25 (3): 130–137. doi:10.1016/j.jmu.2017.08.002. PMC 6029298. PMID 30065477.
  3. ASTLEY R, OLDHAM JS, PARSONS C (July 1953). "Congenital tricuspid atresia". Br Heart J. 15 (3): 287–97. doi:10.1136/hrt.15.3.287. PMC 479498. PMID 13059216.
  4. Unolt M, Putotto C, Silvestri LM, Marino D, Scarabotti A, Valerio M, Caiaro A, Versacci P, Marino B (June 2013). "Transposition of great arteries: new insights into the pathogenesis". Front Pediatr. 1: 11. doi:10.3389/fped.2013.00011. PMC 3860888. PMID 24400257. Vancouver style error: initials (help)

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